GMS 6540 CANPHARM PS3 EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS
What is the process called when two EGFR proteins bind to each other?
Dimerization
In what location does Cetuximab bind EGFR?
Extracellularly
What type of immune cells induce ADCC in cells treated with Cetuximab?
Natural killer cells
If a pt is being treated with Osimertinib, what were they likely treated with
previously?
Erlotinib
What is the endogenous ligand for HER2?
It has no known ligand
A breast cancer pt with a tumor with which characterization would be most likely
to respond to Tamoxifen?
ER+PR-HER2-
Which class of drugs could potentially increase estrogen signaling?
SERMs
Which drug significantly increases the risk of DVTs?
Raloxifene
Which drug is given intramuscularly?
WITH COMPLETE SOLUTIONS
What is the process called when two EGFR proteins bind to each other?
Dimerization
In what location does Cetuximab bind EGFR?
Extracellularly
What type of immune cells induce ADCC in cells treated with Cetuximab?
Natural killer cells
If a pt is being treated with Osimertinib, what were they likely treated with
previously?
Erlotinib
What is the endogenous ligand for HER2?
It has no known ligand
A breast cancer pt with a tumor with which characterization would be most likely
to respond to Tamoxifen?
ER+PR-HER2-
Which class of drugs could potentially increase estrogen signaling?
SERMs
Which drug significantly increases the risk of DVTs?
Raloxifene
Which drug is given intramuscularly?
