GMS 6540 CANPHARM PS2 EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS GRADED A++
Which class of cancer drugs is the least selective towards cancer cells?
Chemotherapy
Is chemotherapy generally more effective when tumors are small or large?
Small
A tumor contains 10^9 cells. After a dose of chemotherapy, there are 750,000
cells remaining. When the second chemotherapy dose is given, the tumor has
grown to 800,000 cells. How many cells do you expect to remain after the next
dose of chemotherapy?
600
Which statement best summarizes the treatment ramifications of the Goldie-
Coldman hypothesis?
Cancer must be treated with more than one drug
Does drug resistance increase or decrease the therapeutic index of cancer
drugs?
Decrease
An inhibitor of what enzyme would be expected to increase the sensitivity of
cancer cells to vincristine?
MDR
WITH COMPLETE SOLUTIONS GRADED A++
Which class of cancer drugs is the least selective towards cancer cells?
Chemotherapy
Is chemotherapy generally more effective when tumors are small or large?
Small
A tumor contains 10^9 cells. After a dose of chemotherapy, there are 750,000
cells remaining. When the second chemotherapy dose is given, the tumor has
grown to 800,000 cells. How many cells do you expect to remain after the next
dose of chemotherapy?
600
Which statement best summarizes the treatment ramifications of the Goldie-
Coldman hypothesis?
Cancer must be treated with more than one drug
Does drug resistance increase or decrease the therapeutic index of cancer
drugs?
Decrease
An inhibitor of what enzyme would be expected to increase the sensitivity of
cancer cells to vincristine?
MDR
