GMS6551 FINAL_5 EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED
factors that influence drug action
- prescribed dose
- administered dose (ADME)
- concentration at site(s) of action
- drug effects
condition or state of being includes
- physiological set-point (i.e., body temp)
- disease-induced alterations in PK
- disease-induced alterations in PD
- age
- reproduction
- allergic rxns
environmental factors include
- diet
- habits
- physical (i.e., sunlight)
genetics (pharmacogenetics) include
- pharmacokinetic (i.e., codeine to morphine metabolization; isoniazid acetylation)
- pharmacodynamic (receptors, enzymes, ion channels)
- PK + PD (warfarin on p450 metabolism and target sensitivity, respectively)
COMPLETE SOLUTIONS VERIFIED
factors that influence drug action
- prescribed dose
- administered dose (ADME)
- concentration at site(s) of action
- drug effects
condition or state of being includes
- physiological set-point (i.e., body temp)
- disease-induced alterations in PK
- disease-induced alterations in PD
- age
- reproduction
- allergic rxns
environmental factors include
- diet
- habits
- physical (i.e., sunlight)
genetics (pharmacogenetics) include
- pharmacokinetic (i.e., codeine to morphine metabolization; isoniazid acetylation)
- pharmacodynamic (receptors, enzymes, ion channels)
- PK + PD (warfarin on p450 metabolism and target sensitivity, respectively)
