WITH COMPLETE SOLUTIONS
basic science research
T0
translation to humans
T1
translation to patients
T2
translation to practice
T3
translation to community
T4
preclinical and animal studies
T0
proof of concept Phase 1 clinical trials
T1
Phase 2 and 3 clinical trials
T2
Phase 4 clinical trials
T3
population-level outcomes research
T4
, defining mechanisms, targets, and lead molecules
T0
new methods of diagnosis, treatment, and prevention
T1
controlled studies leading to effective care
T2
delivery of recommended and timely care to the right patient
T3
true benefit to society
T4
translation from basic science to human studies
T0-T2
translation of new data into the clinic and health decision making
T3-T4
yields knowledge about defining mechanisms, targets, or lead molecules
T0
yields knowledge about new methods of diagnosis, treatment, and prevention
T1
yields knowledge about the efficacy of the interventions in optimal settings
T2
yields knowledge about how interventions work in real-world settings
T3
ultimately results in improved global health