GMS6551 GRADUATION EXAM REVIEW QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
What are the most common drug targets? (examples)
enzymes, receptors, proteins, DNA, RNA
What are the three types of assay development?
in vitro, in vivo, ex vivo
in vitro
test tube
in vivo
living animals
ex vivo
tissues
What are the advantages to in vitro development?
fast, inexpensive, less "red tape"
What are the advantages to in vivo development?
the results are more likely to translate to humans
How can lead compounds be identified?
, in natural products (plants/fungi), chemical banks, drug design (rational and computer-aided)
How are drugs classified?
chemical properties, mechanism of action, disease used to treat, and abuse potential
What is the highest class of controlled substances?
Schedule I
What are some examples of Schedule I drugs?
heroin, LSD, marijuana
Which classifications of controlled substances have high abuse and dependence potential?
Schedule I and II
Schedule I
no currently accepted medical use; cannot be prescribed
What are some examples of Schedule II drugs?
morphine, amphetamines, high dose codeine
Schedule II
no refills allowed; requires written prescription
Which class of controlled substances has moderate abuse potential?
Schedule III
What are some examples of Schedule III drugs?
ketamine, low dose codeine
ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
What are the most common drug targets? (examples)
enzymes, receptors, proteins, DNA, RNA
What are the three types of assay development?
in vitro, in vivo, ex vivo
in vitro
test tube
in vivo
living animals
ex vivo
tissues
What are the advantages to in vitro development?
fast, inexpensive, less "red tape"
What are the advantages to in vivo development?
the results are more likely to translate to humans
How can lead compounds be identified?
, in natural products (plants/fungi), chemical banks, drug design (rational and computer-aided)
How are drugs classified?
chemical properties, mechanism of action, disease used to treat, and abuse potential
What is the highest class of controlled substances?
Schedule I
What are some examples of Schedule I drugs?
heroin, LSD, marijuana
Which classifications of controlled substances have high abuse and dependence potential?
Schedule I and II
Schedule I
no currently accepted medical use; cannot be prescribed
What are some examples of Schedule II drugs?
morphine, amphetamines, high dose codeine
Schedule II
no refills allowed; requires written prescription
Which class of controlled substances has moderate abuse potential?
Schedule III
What are some examples of Schedule III drugs?
ketamine, low dose codeine
