©FYNDLAY EXAM SOLUTIONS 2024/2025
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Advanced Biochemistry Final Exam Study
Guide.
N5,N10-methylene-THF - answer✔directly used to convert uracils to thymines
5-methyl uracil - answer✔N5,N10-methylene-THF methylates where
N5-methyl-THF - answer✔used to remethylate homocysteine
folic acid - answer✔typical nature of the supplement found in USA wheat flour to provide
methylated forms of THF.
DHF - answer✔normal substrate for the enzyme inhibited by methotrexate (an early
chemotherapeutic agent).
Trimethoprim - answer✔inhibitor of DHF reductase found in a widely distributed "sulfa drug"
Acyclovir - answer✔toxic agent avidly activated by herpes thymine kinase
Replication - answer✔what process does acyclovir inhibit
Doxyclycline - answer✔inhibitor of A site occupancy by aminoacyl-tRNAs?
concentrated - answer✔Doxycline affects bacteria because it is?
increases Uracils in DNA because you cannot change from Uracils to Thymines which will
ultimately cause apoptosis due to too much gaps in the DNA - answer✔lack of folic acid
Takes the Uracils out of the DNA in order for repair endonuclease to "fix" the DNA -
answer✔Uracil DNA glycosylase
activates apoptosis - answer✔double-strand and single- strand breaks in DNA caused by
damage
activates expression of Nox2 which produces O radicals which activate s-nitrosohomocysteine -
answer✔homocysteine activates?
Glutathione - answer✔cysteine is important in making
rrpsy - answer✔recognition sequence for pka
1|Page
, ©FYNDLAY EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
bZIP proteins - answer✔Basic and Leucine zipper (CREB)
CREB - answer✔cAMP response element binding protein
transcription factor
histone acetyltransferase (HAT) - answer✔unwraps the DNA (acetylation)
CARM1/PRMT - answer✔Methylates CBP
Flavin - answer✔
Ribose - answer✔What is flavin attached to?
Histidine - answer✔Imidazole that flavin is attached to
Guanine - answer✔
G-cap - answer✔modification of guanine
Adenine - answer✔
Nicotinamide - answer✔
Thymine - answer✔
Cytosine - answer✔
Uracil - answer✔
1 - answer✔Which numbered atom bonds to the 1' carbon of ribose?
5 (thymine) - answer✔Which numbered atom would receive a hydrophobic group added by
N5,N10-methylene- tetrahydrofolate?
4 - answer✔Which numbered atom has an attached atom that makes a hydrogen bond to
adenine's exocyclic amino group?
6 on adenine - answer✔to what numbered carbon is adenine's exocyclic amino group
attached?
9 on adenine and 1 on uracil - answer✔to what numbered atom is the 1' carbon of ribose
attached on adenine?
3 - answer✔Which numbered atom has an attached atom that makes a hydrogen bond to
adenine's N1
MILK WHVTF - answer✔essential amino acids (a.a. that you cannot make)
2|Page
ALL RIGHTS RESERVED.
Advanced Biochemistry Final Exam Study
Guide.
N5,N10-methylene-THF - answer✔directly used to convert uracils to thymines
5-methyl uracil - answer✔N5,N10-methylene-THF methylates where
N5-methyl-THF - answer✔used to remethylate homocysteine
folic acid - answer✔typical nature of the supplement found in USA wheat flour to provide
methylated forms of THF.
DHF - answer✔normal substrate for the enzyme inhibited by methotrexate (an early
chemotherapeutic agent).
Trimethoprim - answer✔inhibitor of DHF reductase found in a widely distributed "sulfa drug"
Acyclovir - answer✔toxic agent avidly activated by herpes thymine kinase
Replication - answer✔what process does acyclovir inhibit
Doxyclycline - answer✔inhibitor of A site occupancy by aminoacyl-tRNAs?
concentrated - answer✔Doxycline affects bacteria because it is?
increases Uracils in DNA because you cannot change from Uracils to Thymines which will
ultimately cause apoptosis due to too much gaps in the DNA - answer✔lack of folic acid
Takes the Uracils out of the DNA in order for repair endonuclease to "fix" the DNA -
answer✔Uracil DNA glycosylase
activates apoptosis - answer✔double-strand and single- strand breaks in DNA caused by
damage
activates expression of Nox2 which produces O radicals which activate s-nitrosohomocysteine -
answer✔homocysteine activates?
Glutathione - answer✔cysteine is important in making
rrpsy - answer✔recognition sequence for pka
1|Page
, ©FYNDLAY EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
bZIP proteins - answer✔Basic and Leucine zipper (CREB)
CREB - answer✔cAMP response element binding protein
transcription factor
histone acetyltransferase (HAT) - answer✔unwraps the DNA (acetylation)
CARM1/PRMT - answer✔Methylates CBP
Flavin - answer✔
Ribose - answer✔What is flavin attached to?
Histidine - answer✔Imidazole that flavin is attached to
Guanine - answer✔
G-cap - answer✔modification of guanine
Adenine - answer✔
Nicotinamide - answer✔
Thymine - answer✔
Cytosine - answer✔
Uracil - answer✔
1 - answer✔Which numbered atom bonds to the 1' carbon of ribose?
5 (thymine) - answer✔Which numbered atom would receive a hydrophobic group added by
N5,N10-methylene- tetrahydrofolate?
4 - answer✔Which numbered atom has an attached atom that makes a hydrogen bond to
adenine's exocyclic amino group?
6 on adenine - answer✔to what numbered carbon is adenine's exocyclic amino group
attached?
9 on adenine and 1 on uracil - answer✔to what numbered atom is the 1' carbon of ribose
attached on adenine?
3 - answer✔Which numbered atom has an attached atom that makes a hydrogen bond to
adenine's N1
MILK WHVTF - answer✔essential amino acids (a.a. that you cannot make)
2|Page
