NARM STUDY: MIA MODULE 4, PRENATAL TESTING AND RISK SCREENING

NARM STUDY: MIA MODULE 4, PRENATAL TESTING AND RISK
SCREENING

Varicella in pregnancy --> maternal complications:
Varicella pneumonia
death
Varicella in pregnancy --> fetal complications:
congenital varicella syndrome:
especially <20w
25-40% risk
eye and CNS damage
limb hypoplasia
scars
Varicella in late pregnancy (6d before labor through 2d PP) --> neonatal
complications:
neonatal infection s passive immunity -->
5% mortality rate
Untreated chlamydia -->
ectopic pregnancy
PROM/PTL
vertical transmission at birth
untreated gonorrhea -->
PROM/PTL
ophthalmia neonatorum
ascending infection during PP
untreated syphillis -->
transplacental transmission
40% risk: abortion, stillbirth, perinatal death
40% risk: congenital syphillis, lesions in internal organs and long bones, death
active HSV outbreak @birth -->
transmission with ROM
50% rate transmission @ birth
risk of transmission after birth
neonatal infection --> 60% mortality
genital warts (HSV/condylomata acuminata) -->
excessive bleeding if torn
neonatal laryngeal pappilomatosis
rubella contracted in 1st trimester -->
miscarriage, stillbirth
anomalies
52% risk of CRS:
growth retardation, CHD, CNS defects, cranial defects
cytamegalovirus in pregnancy -->
fetal defects of vision and hearing, mental retardation