PATH 1000 UNIT 5 EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED
Hormones: are? function?
Chemical messengers
Regulatory functions (energy metabolism, growth & development, fluid & electrolyte
balance, sexual development & reproduction, mood & psychological balance)
Hormonal Regulation: hypothalamic-pituitary axis function? how to hormones
achieve an action? type of communication?
Controls hormone initiation & regulation (+ & - feedback loops)
By combining with target organs or glands through receptor binding
Intracellular
Receptor Binding: allows? hormones seek?
Hormones to act selectively on certain cells
Seek out and attach to specific receptors
Etiology of disorders: dysfunction of HP axis? altered receptor binding?
endocrine gland damage? other?
Damage to feed back mechanisms
Hypo-responsiveness of hormone receptors
Response to neuroendocrine message
Inactivation of hormones by antibodies
Syndrome of Inappropriate Antidiuretic Hormone: define. role of ADH? etiology?
list a few types of cancers that can cause this
, Group of symptoms that develop when there is too much ADH in the body
Regulates balance of fluids in the body (lowers amount of urine the body makes
and increases amount of water kidneys take up)
Ectopic secretion by tumor cells, CNS disorders, pulmonary disorders, medications
Bladder cancer, prostate cancer, pancreatic cancer, uterine cancer etc.
SIADH (etiology): based on oncology?
May be a result of ectopic arginine vasopressin (AVP) production by tumor cells or a
result of stimulation of AVP secretion or potentiation of AVP effects by anticancer
drugs of palliative care medications
SIADH: pathophysiology?
Increased levels of ADH
Increased renal water retention
Increased ECF volume
Resulting in hyponatremia
SIADH: clinical manifestations? symptoms get worse when?
Thirst, anorexia, hypervolemia & weight gain, coma, seizures, confusion, lethargy,
vomiting, cramps, fatigue
Na+ loss goes up (related to hyponatremia)
SIADH: how are pulmonary diseases associated?
Pulmonary diseases (like COPD) can cause SIADH due to renal vasoconstriction &
antidiuresis in response to hypercapnia (renal response eventually leads
to hyponatremia due to water retention)
Diabetes Insipidus: insufficiency of? (symptoms?) classifications? (mean?)
COMPLETE SOLUTIONS VERIFIED
Hormones: are? function?
Chemical messengers
Regulatory functions (energy metabolism, growth & development, fluid & electrolyte
balance, sexual development & reproduction, mood & psychological balance)
Hormonal Regulation: hypothalamic-pituitary axis function? how to hormones
achieve an action? type of communication?
Controls hormone initiation & regulation (+ & - feedback loops)
By combining with target organs or glands through receptor binding
Intracellular
Receptor Binding: allows? hormones seek?
Hormones to act selectively on certain cells
Seek out and attach to specific receptors
Etiology of disorders: dysfunction of HP axis? altered receptor binding?
endocrine gland damage? other?
Damage to feed back mechanisms
Hypo-responsiveness of hormone receptors
Response to neuroendocrine message
Inactivation of hormones by antibodies
Syndrome of Inappropriate Antidiuretic Hormone: define. role of ADH? etiology?
list a few types of cancers that can cause this
, Group of symptoms that develop when there is too much ADH in the body
Regulates balance of fluids in the body (lowers amount of urine the body makes
and increases amount of water kidneys take up)
Ectopic secretion by tumor cells, CNS disorders, pulmonary disorders, medications
Bladder cancer, prostate cancer, pancreatic cancer, uterine cancer etc.
SIADH (etiology): based on oncology?
May be a result of ectopic arginine vasopressin (AVP) production by tumor cells or a
result of stimulation of AVP secretion or potentiation of AVP effects by anticancer
drugs of palliative care medications
SIADH: pathophysiology?
Increased levels of ADH
Increased renal water retention
Increased ECF volume
Resulting in hyponatremia
SIADH: clinical manifestations? symptoms get worse when?
Thirst, anorexia, hypervolemia & weight gain, coma, seizures, confusion, lethargy,
vomiting, cramps, fatigue
Na+ loss goes up (related to hyponatremia)
SIADH: how are pulmonary diseases associated?
Pulmonary diseases (like COPD) can cause SIADH due to renal vasoconstriction &
antidiuresis in response to hypercapnia (renal response eventually leads
to hyponatremia due to water retention)
Diabetes Insipidus: insufficiency of? (symptoms?) classifications? (mean?)
