BCH 451 FINAL EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED
Accounts for the temperature dependence of the rate of a reaction.
Arrhenius Equation
______ base pairs are less stable than ______ base pairs
AT, GC
Two chemical modes of catalysis
Acid-Base, Covalent group transfer
Characteristics of B DNA
2' endo sugar pucker, Bases perpendicular to helical axis, base pairs cross center of
helix, longer more narrow helix
Characteristics of A DNA
3' endo sugar pucker, base pairs tilted 20 degree angle from helix axis, central axial
cavity in helix, shorter fatter helix
______ of enzyme catalysis occurs when an inhibitor binds to the active site of
the enzyme
Competitive inhibition
The _____ postulates that a constant input feed of substrate is supplied whoms
rate equals that of product formation
Steady State Approximation
The 2' hydroxyl group catalyzes _______ of RNA, a good example of ________
assistance in a non-protein biomolecular mechanism.
, Alkaline hydrolysis, anchiomeric
An antisense oligonucleotide functionally inactivates a mRNA for use in
translation by a ribosome by forming a double helix with it and precluding ______
binding.
tRNA anticodon
Name the two most prevalent classes of RNA.
tRNA and rRNA
Two external factors that limit the velocity of an enzymatic reaction.
pH and Temperature
Two internal factors that limit the velocity of an enzymatic reaction.
hydrophobic effect and hydrogen bonding
Pyridine Aldoximine Methiodide (PAM) reactivates acetylcholine esterase,
functioning as a _______.
Nerve gas antidote
Two distinctive features of eukaryotic mRNA are
Poly (A) tail, introns and exons
What kind of reaction produces the reactivated acetylcholine esterase enzyme
thanks to PAM?
Nucleophilic substitution
Used to detect the presence of a specific complementary nucleic acid sequence
DNA probe
What amino acid and functional group in the esterase site of acetylcholine
esterase reacts with the substrate?
COMPLETE SOLUTIONS VERIFIED
Accounts for the temperature dependence of the rate of a reaction.
Arrhenius Equation
______ base pairs are less stable than ______ base pairs
AT, GC
Two chemical modes of catalysis
Acid-Base, Covalent group transfer
Characteristics of B DNA
2' endo sugar pucker, Bases perpendicular to helical axis, base pairs cross center of
helix, longer more narrow helix
Characteristics of A DNA
3' endo sugar pucker, base pairs tilted 20 degree angle from helix axis, central axial
cavity in helix, shorter fatter helix
______ of enzyme catalysis occurs when an inhibitor binds to the active site of
the enzyme
Competitive inhibition
The _____ postulates that a constant input feed of substrate is supplied whoms
rate equals that of product formation
Steady State Approximation
The 2' hydroxyl group catalyzes _______ of RNA, a good example of ________
assistance in a non-protein biomolecular mechanism.
, Alkaline hydrolysis, anchiomeric
An antisense oligonucleotide functionally inactivates a mRNA for use in
translation by a ribosome by forming a double helix with it and precluding ______
binding.
tRNA anticodon
Name the two most prevalent classes of RNA.
tRNA and rRNA
Two external factors that limit the velocity of an enzymatic reaction.
pH and Temperature
Two internal factors that limit the velocity of an enzymatic reaction.
hydrophobic effect and hydrogen bonding
Pyridine Aldoximine Methiodide (PAM) reactivates acetylcholine esterase,
functioning as a _______.
Nerve gas antidote
Two distinctive features of eukaryotic mRNA are
Poly (A) tail, introns and exons
What kind of reaction produces the reactivated acetylcholine esterase enzyme
thanks to PAM?
Nucleophilic substitution
Used to detect the presence of a specific complementary nucleic acid sequence
DNA probe
What amino acid and functional group in the esterase site of acetylcholine
esterase reacts with the substrate?
