Questions & Answers: latest Updated A+ Guide
What does the Public Service Policy on Humane Care and Use of Laboratory Animal
(PHS Policy) implement? - ANSWERthe Health Research Extension Act of 1985
The Health Research Extension Act of 1985 directs ______ to establish guidelines for
the proper care and treatment of animals used in research - ANSWERthe Secretary
of Health and Human Services
In 1986, the PHS Policy incorporated the ________ by the Interagency Research
Animal Committee and adopted by US Government agencies that use vertebrate
animals - ANSWERU.S. Government Principles for the Utilization and Care of
Vertebrate Animals Used in Testing, Research, and Training
IACUC membership requirements for PHS Assurance - ANSWER5 members:
One veterinarian (training/experience in lab animal medicine)
One scientist (experience in research)
One nonscientific member
One not affiliated member
PHS Policy mandates that animal care and use programs must operate in accordance
with four specific laws and guidelines - ANSWER1. The Animal Welfare Act
2. United States Government Principles for the Utilization and Care of Vertebrate
Animals Used in Testing, Research, and Training
3. The Guide for the Care and Use of Laboratory Animals
4. AVMA Guidelines for the Euthanasia of Animals
Code of Federal Regulations, Title 9, Chapter 1, Subchapter A, Parts 1, 2, and 3 -
ANSWERAnimal Welfare Regulations that are implemented by the USDA/APHIS/AC
Clarified humane care, minimization of pain and distress, consideration of
alternatives, institutional animal care and use committees, psychological well-being
of primates, and exercise for dogs - ANSWER1985 amendments to the AWA
Which term is defined in the Guide as "all measures to control known or unknown
infections in laboratory animals."
a. Biosecurity
b. Stabilization
c. Quarantine
d. Biosafety - ANSWERa. Biosecurity
Which of the following statements about multiple survival surgical procedures on a
single animal is TRUE?
a. The Guide's definition of "major" surgery is rigid, and does not provide for any
interpretation by the veterinarian or the IACUC.
, b. When USDA-covered species are used, the Animal Welfare Regulations' definition
of "major" surgery takes precedence.
c. The Animal Welfare Regulations allow for the interpretation of "major" surgery to
be evaluated on a case-by-case basis by the IACUC.
d. The Guide's requirement that multiple major survival surgeries must be
scientifically justified and included in the IACUC-approved protocol only applies to
non-rodent mammals. - ANSWERb. When USDA-covered species are used, the
Animal Welfare Regulations' definition of "major" surgery takes precedence.
Animals using which type of thermoregulation depend mostly on environmental
temperature to maintain their internal physiology? - ANSWERPoikilothermic
Which should be provided in the environment of a semi-aquatic animal?
a. porous substrate
b. recirculating system
c. a terrestrial area
d. low humidity level - ANSWERc. a terrestrial area
Which statement is TRUE for the use of agricultural animals in biomedical research,
when they are maintained in a farm setting?
a. These animals are covered by the Guide but not by the Animal Welfare Act.
b. These animals are only covered by the Ag Guide.
c. These animals are covered by the Animal Welfare Act but not by the Guide.
d. These animals are covered by the Guide but will benefit from the principles and
practices detailed in the Ag Guide. - ANSWERd. These animals are covered by the
Guide but will benefit from the principles and practices detailed in the Ag Guide.
What is the minimum space required for a female mouse and her litter?
a. 75 in2
b. 51 in2
c. 330 in2
d. 124 in2 - ANSWERb. 51 in2
Which are used to standardize the method for performing specific institutional
practices and procedures?
a. Policies
b. Performance Standards
c. Procedures
d. Principles - ANSWERc. Procedures
The first version of the current Animal Welfare Act - ANSWERLaboratory Animal
Welfare Act of 1966
The Act was amended in 1970 and named the Animal Welfare Act
1976 Amendment to the AWA - ANSWERExpanded to cover common carriers (for
example, airlines and trucking companies) and to set standards for animal