(All Inclusive) BOC Chemistry (MLT only) Practice Test|
MLT Chemistry | MLT Clinical Chemistry (MEDICAL
LABORATORY TECHNICIANS Chemistry) Questions Ansd
Answers /2024/2025 Gurantee Guide
9. Serum levels that define hypoglycemia in pre-term or low birth weight infants are
a. the same as adults
b. lower than adults
c. the same as a normal full term infant
d. higher than a normal full term infant - ANSWERb
12. In the fasting state, the arterial and capillary blood glucose concentration varies
from venous glucose concentration by approximately how many mg/dL?
a. 1 mg/dL
b. 5 mg/dL
c. 10 mg/dL
d. 15 mg/dL - ANSWERb
16. A patient with type I, insulin dependent DM has the following results
Fasting blood glucose: 150 mg/dL (70-110 mg/dL)
HgbA1C: 8.5% (4-6%)
Fructosamine 2.5 mmol/L (2-2.9 mmol/L)
After reviewing these test results, the technologist concluded that the patient is in a
a. steady state of metabolic control
b. state of flux, progressively worsening metabolic control
c. improving state of metabolic control as indicated by fructosamine
d. state of flux as indicted by the fasting glucose level - ANSWERc
19. A patient with hemolytic anemia will
a. show a decrease in glycated Hgb value
b. show an increase in glycated Hgb value
c. show little or no change in glycated Hgb value
d. demonstrate an elevated HgbA - ANSWERa (life of RBCs directly related to
glycated hgb)
20. In using ion-exchange chromatographic methods, falsely increased levels of
HgbA1c might be demonstrated in the presence of
a. iron deficiency anemia
b. pernicious anemia
c. thalassemias
d. HgbS - ANSWERd
23. Blood samples were collected at the beginning of an exercise class and after
thirty minutes of aerobic activity. Which of the following would be most consistent
with the post exercise sample?
,a. normal lactic acid, low pyruvate
b. low lactic acid, elevated pyruvate
c. elevated lactic acid, low pyruvate
d. elevated lactic acid, elevated pyruvate - ANSWERd
25. The different water content of erythrocytes and plasma makes true glucose
concentration in whole blood a function of the
a. hematocrit
b. leucocyte count
c. erythrocyte count
d. erythrocyte indices - ANSWERa (glucose is measured in the water of the sample,
not the cells)
28. One international unit of enzyme activity is the amount of enzyme that will,
under specified reaction conditions of substrate concentration, pH, and temperature
cause utilization of substrate at the rate of
a. 1 mol/min
b. 1 mmol/min
c. 1 umol/min
d. 1 nmol/min - ANSWERc
30. The most specific method for the assay of glucose in all body fluids utilizes
a. hexokinase
b. glucose oxidase
c. glucose-6-phosphatase
d. glucose dehydrogenase - ANSWERa
31. Which of the following would be an example of a glucose-specific colorimetric
method?
a. alkaline ferricyanide
b. glucose oxidase
c. hexokinase
d. o-toluidine - ANSWERb
32. Increased concentrations of ascorbic acid inhibit chromogen production in which
of the following commonly used glucose methods?
a. ferricyanide
b. ortho-toluidine
c. glucose oxidase (peroxidase)
d. hexokinase - ANSWERc
34. Which of the following is a glycolytic enzyme that catalyzes the cleavage of
fructose-1,6-diphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone
phosphate?
a. aldolase
b. phosphofructokinase
c. pyruvate kinase
, d. glucose-6-phosphate dehydrogenase (G6PD) - ANSWERa
36. The most consistent analytical error involved in the routine determination of HDL
cholesterol is caused by
a. incomplete precipitation of LDL cholesterol
b. coprecipitation of HDL and LDL cholesterol
c. inaccurate protein estimation of HDL cholesterol
d. a small concentration of apoB-containing lipoproteins after precipitation -
ANSWERd
37. If the LDL cholesterol is to be calculated by the Friedewald formula, what are the
2 measurements that need to be carried out by the same chemical procedure?
a. total cholesterol and HDL cholesterol
b. total cholesterol and triglyceride
c. triglyceride and chylomicrons
d. apolipoprotein A and apolipoprotein B - ANSWERa
41. Transportaion of 60-75% of the plasma cholesterol is performed by
a. chylomicrons
b. very low density lipoproteins
c. low density lipoproteins
d. high density lipoproteins - ANSWERc
42. Which of the following diseases results from a familial absence of high density
lipoproteins?
a. Krabbe disease
b. Gaucher disease
c. Tangier disease
d. Tay-Sachs disease - ANSWERc
43. A 1 year old girl with a hyperlipoproteinemia and lipoprotein lipase deficiency
has the following lipid profile
Cholesterol: 300 mg/dL
LDL: increased
HDL: decreased
Triglycerides: 1200 mg/dL
Chylomicrons: present
A serum specimen that was refrigerated overnight would most likely be
a. clear
b. cloudy
c. creamy layer over cloudy serum
d. creamy layer over clear serum - ANSWERd (chylomicrons floating on top)
45. A 9 month old boy from Israel has gradually lost the ability to sit up and develops
seizures. He has an increased amount of a phospholipid called GM2-ganglioside in
his neurons and he lacks the enzyme hexosaminidase A in his leukocytes. These
findings suggest
MLT Chemistry | MLT Clinical Chemistry (MEDICAL
LABORATORY TECHNICIANS Chemistry) Questions Ansd
Answers /2024/2025 Gurantee Guide
9. Serum levels that define hypoglycemia in pre-term or low birth weight infants are
a. the same as adults
b. lower than adults
c. the same as a normal full term infant
d. higher than a normal full term infant - ANSWERb
12. In the fasting state, the arterial and capillary blood glucose concentration varies
from venous glucose concentration by approximately how many mg/dL?
a. 1 mg/dL
b. 5 mg/dL
c. 10 mg/dL
d. 15 mg/dL - ANSWERb
16. A patient with type I, insulin dependent DM has the following results
Fasting blood glucose: 150 mg/dL (70-110 mg/dL)
HgbA1C: 8.5% (4-6%)
Fructosamine 2.5 mmol/L (2-2.9 mmol/L)
After reviewing these test results, the technologist concluded that the patient is in a
a. steady state of metabolic control
b. state of flux, progressively worsening metabolic control
c. improving state of metabolic control as indicated by fructosamine
d. state of flux as indicted by the fasting glucose level - ANSWERc
19. A patient with hemolytic anemia will
a. show a decrease in glycated Hgb value
b. show an increase in glycated Hgb value
c. show little or no change in glycated Hgb value
d. demonstrate an elevated HgbA - ANSWERa (life of RBCs directly related to
glycated hgb)
20. In using ion-exchange chromatographic methods, falsely increased levels of
HgbA1c might be demonstrated in the presence of
a. iron deficiency anemia
b. pernicious anemia
c. thalassemias
d. HgbS - ANSWERd
23. Blood samples were collected at the beginning of an exercise class and after
thirty minutes of aerobic activity. Which of the following would be most consistent
with the post exercise sample?
,a. normal lactic acid, low pyruvate
b. low lactic acid, elevated pyruvate
c. elevated lactic acid, low pyruvate
d. elevated lactic acid, elevated pyruvate - ANSWERd
25. The different water content of erythrocytes and plasma makes true glucose
concentration in whole blood a function of the
a. hematocrit
b. leucocyte count
c. erythrocyte count
d. erythrocyte indices - ANSWERa (glucose is measured in the water of the sample,
not the cells)
28. One international unit of enzyme activity is the amount of enzyme that will,
under specified reaction conditions of substrate concentration, pH, and temperature
cause utilization of substrate at the rate of
a. 1 mol/min
b. 1 mmol/min
c. 1 umol/min
d. 1 nmol/min - ANSWERc
30. The most specific method for the assay of glucose in all body fluids utilizes
a. hexokinase
b. glucose oxidase
c. glucose-6-phosphatase
d. glucose dehydrogenase - ANSWERa
31. Which of the following would be an example of a glucose-specific colorimetric
method?
a. alkaline ferricyanide
b. glucose oxidase
c. hexokinase
d. o-toluidine - ANSWERb
32. Increased concentrations of ascorbic acid inhibit chromogen production in which
of the following commonly used glucose methods?
a. ferricyanide
b. ortho-toluidine
c. glucose oxidase (peroxidase)
d. hexokinase - ANSWERc
34. Which of the following is a glycolytic enzyme that catalyzes the cleavage of
fructose-1,6-diphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone
phosphate?
a. aldolase
b. phosphofructokinase
c. pyruvate kinase
, d. glucose-6-phosphate dehydrogenase (G6PD) - ANSWERa
36. The most consistent analytical error involved in the routine determination of HDL
cholesterol is caused by
a. incomplete precipitation of LDL cholesterol
b. coprecipitation of HDL and LDL cholesterol
c. inaccurate protein estimation of HDL cholesterol
d. a small concentration of apoB-containing lipoproteins after precipitation -
ANSWERd
37. If the LDL cholesterol is to be calculated by the Friedewald formula, what are the
2 measurements that need to be carried out by the same chemical procedure?
a. total cholesterol and HDL cholesterol
b. total cholesterol and triglyceride
c. triglyceride and chylomicrons
d. apolipoprotein A and apolipoprotein B - ANSWERa
41. Transportaion of 60-75% of the plasma cholesterol is performed by
a. chylomicrons
b. very low density lipoproteins
c. low density lipoproteins
d. high density lipoproteins - ANSWERc
42. Which of the following diseases results from a familial absence of high density
lipoproteins?
a. Krabbe disease
b. Gaucher disease
c. Tangier disease
d. Tay-Sachs disease - ANSWERc
43. A 1 year old girl with a hyperlipoproteinemia and lipoprotein lipase deficiency
has the following lipid profile
Cholesterol: 300 mg/dL
LDL: increased
HDL: decreased
Triglycerides: 1200 mg/dL
Chylomicrons: present
A serum specimen that was refrigerated overnight would most likely be
a. clear
b. cloudy
c. creamy layer over cloudy serum
d. creamy layer over clear serum - ANSWERd (chylomicrons floating on top)
45. A 9 month old boy from Israel has gradually lost the ability to sit up and develops
seizures. He has an increased amount of a phospholipid called GM2-ganglioside in
his neurons and he lacks the enzyme hexosaminidase A in his leukocytes. These
findings suggest
