MLT 126 - immunology & serology -Final Exam Review
Guide (Latest 2024/2025) (500 Q&A)
Which of the following is part of innate immunity?
i. NK cell
ii. LGL
iii. Null cell
iv. T cell
a. I
b. I, II
c. I, II, III
d. I, II, III, IV - ANSWERc. I, II, III
Defects in which arm of the immune system ate most commonly associated with
severe illness after administration of live virus vaccines?
a. Cell-mediated immunity
b. Humoral immunity
c. Complement
d. Phagocytic cells - ANSWERa. Cell-mediated immunity
All of the following are characteristics of NK cells, except:
a. Contains azurophilic granules
b. Approximately 15 um
c. Ground glass appearance of cytoplasm
d. Indented nucleus - ANSWERc. Ground glass appearance of cytoplasm
MHC molecules found primarily in antigen presenting cells, which include B
lymphocytes, monocytes, macrophages, and dendritic cells?
a. MHC class I
b. MHC class II
c. MHC class III
d. MHC class IV - ANSWERb. MHC class II
Nature of infecting antigen for cell-mediated immunity:
a. Intracellular
b. Extracellular
c. In-vitro
d. Intracellular and In-vitro - ANSWERa. Intracellular
, In an agglutination reaction, if cells are not centrifuged long enough, which of the
following might occur?
a. False-negative result
b. False-positive result
c. No effect
d. Slight effect but can be ignored - ANSWERa. False-negative result
All of the following are functions of secondary lymphoid organs except:
a. Initiate most immune responses
b. Antigen trapping site
c. Generation and differentiation of lymphocytes
d. Signals lymphocytes to go back to blood stream - ANSWERc. Generation and
differentiation of lymphocytes
The double negative stage of T cell maturation is characterized by the following
except:
a. There is an orderly rearrangement of the genes coding for the antigen receptor
(TCR)
b. CD4 and CD8 negative
c. Rearrangement of genes coding for HC and LC
d. None of the above - ANSWERc. Rearrangement of genes coding for HC and LC
Humoral immunity has a primary defense against?
a. Extracellular infection
b. Intracellular infection
c. Tumors
d. Graft - ANSWERa. Extracellular infection
Receptor of SRBCs on T-cells
a. CD21
b. CD35
c. CD16
d. CD2 - ANSWERd. CD2
Neutrophils found on the blood vessel walls
a. Aggregating neutrophils
b. Phagocytic neutrophils
c. Marginating neutrophils
d. Circulating neutrophils - ANSWERc. Marginating neutrophils
Mechanism of action of Basophil?
a. Release histamine directly from the tissue
b. Attach IgE containing antigen before release of
granules
Guide (Latest 2024/2025) (500 Q&A)
Which of the following is part of innate immunity?
i. NK cell
ii. LGL
iii. Null cell
iv. T cell
a. I
b. I, II
c. I, II, III
d. I, II, III, IV - ANSWERc. I, II, III
Defects in which arm of the immune system ate most commonly associated with
severe illness after administration of live virus vaccines?
a. Cell-mediated immunity
b. Humoral immunity
c. Complement
d. Phagocytic cells - ANSWERa. Cell-mediated immunity
All of the following are characteristics of NK cells, except:
a. Contains azurophilic granules
b. Approximately 15 um
c. Ground glass appearance of cytoplasm
d. Indented nucleus - ANSWERc. Ground glass appearance of cytoplasm
MHC molecules found primarily in antigen presenting cells, which include B
lymphocytes, monocytes, macrophages, and dendritic cells?
a. MHC class I
b. MHC class II
c. MHC class III
d. MHC class IV - ANSWERb. MHC class II
Nature of infecting antigen for cell-mediated immunity:
a. Intracellular
b. Extracellular
c. In-vitro
d. Intracellular and In-vitro - ANSWERa. Intracellular
, In an agglutination reaction, if cells are not centrifuged long enough, which of the
following might occur?
a. False-negative result
b. False-positive result
c. No effect
d. Slight effect but can be ignored - ANSWERa. False-negative result
All of the following are functions of secondary lymphoid organs except:
a. Initiate most immune responses
b. Antigen trapping site
c. Generation and differentiation of lymphocytes
d. Signals lymphocytes to go back to blood stream - ANSWERc. Generation and
differentiation of lymphocytes
The double negative stage of T cell maturation is characterized by the following
except:
a. There is an orderly rearrangement of the genes coding for the antigen receptor
(TCR)
b. CD4 and CD8 negative
c. Rearrangement of genes coding for HC and LC
d. None of the above - ANSWERc. Rearrangement of genes coding for HC and LC
Humoral immunity has a primary defense against?
a. Extracellular infection
b. Intracellular infection
c. Tumors
d. Graft - ANSWERa. Extracellular infection
Receptor of SRBCs on T-cells
a. CD21
b. CD35
c. CD16
d. CD2 - ANSWERd. CD2
Neutrophils found on the blood vessel walls
a. Aggregating neutrophils
b. Phagocytic neutrophils
c. Marginating neutrophils
d. Circulating neutrophils - ANSWERc. Marginating neutrophils
Mechanism of action of Basophil?
a. Release histamine directly from the tissue
b. Attach IgE containing antigen before release of
granules
