HEMATOLOGY/IMMUNOLOGY CCRN- Critical Care
Registered Nurse Study Questions 2024/2025
Completely Solved 100%
platelets are made where
info on platelets - ANSWERbone marrow and are the smallest type of blood cell
they are white blood cells that live 7-10 days
platelet plug is effective for small injuries
bleeding time measures
platelet count measures - ANSWERbleeding time-platelet function how well platelets
work
platelet count-quantity of platelet
physio of platelet/white clot formation
start with activated platelets end with platelet plug forms 1-4 mins after injury -
ANSWERactivated platelets secrete ADP->activation ofCOX pathway->phospholipase
2 mediated->thromboxane A2 production->further activation ofplatelets to area -
>platelet plug
coag pathways activated by extrinsic or intrisic pathways
describe common coag. pathway - ANSWERextrinsic or intrinsic pathway triggers....
activation of factor x->
conversion of prothrombin->
thrombin->
fibrinogen->
fibrin->
fibrin mesh clot
what point in common coag pathway does coumadin work? - ANSWERat the
conversion of prothrombin to thrombin
inhibits vitamin K
what point in common coag pathway does heparin work? - ANSWERthrombin to.
fibrinogen
inhibits thrombin
intrinsic coag pathway is stimulated by what - ANSWERvascular endothelial injury
like...
cell trauma-valve, IABP
sepsis
shock
ARDS
hypoxemia/acidemia
cardiopulmonary arrest
, extrinsic coag pathway is stimulated by what - ANSWERtissue injury and releases
tissue thromboplastin...
extensive trauma
OB emergencies
malignanceis
dissecting aortic aneurysm
extensive MI
patho of inhibition of clot formation/clot breakdown starting at clot/thrombin -
ANSWERthrombin->
plasminogen->
plasmin->
lysosomal enzymes->
splitting of fibrin and fibrinogen->
formation of fibrin split products FSPs
reversal of heparin? - ANSWERprotamine
reversal of warfarin/coumadin? - ANSWERvitmamin K
DIC is caused by what - ANSWERactivation of clotting -fibrinolytic system with
resultant consumption of clotting factors
lab values for DIC in primary DIC what do you see - ANSWERdecreased platelets,
fibrinogen, hematocrit
increased FSP-due to increased fibrinolysis
increased PT, PTT, INR, bleed time
lab values in DIC secondary - ANSWERincreased D dimer-assesses presence of clots
increased antithrombin 3
DIC is primarily a _ problem - ANSWERclotting
not bleeding
DIC is always _ to another problem - ANSWERsecondary
causes of DIC 4 categories and give examples
1. endothelial damage
2. release of tissue thromboplastin
3. factor x activation
4. micellaneous - ANSWER1. endothelial damage-sepsis, hypoxemia, shock, ARDS,
AAA, acidemia, CPR
2. release of tissue thromboplastin-extensive trauma, malignancies, OB emergencies,
dssecting aortic aneurysm
3. factor x activation-acute pancreatitis, livr disease
4. micellaneous-massive transfusions, PE, hemolytic anemia, fresh water drowning,
aspirin poisoning
Registered Nurse Study Questions 2024/2025
Completely Solved 100%
platelets are made where
info on platelets - ANSWERbone marrow and are the smallest type of blood cell
they are white blood cells that live 7-10 days
platelet plug is effective for small injuries
bleeding time measures
platelet count measures - ANSWERbleeding time-platelet function how well platelets
work
platelet count-quantity of platelet
physio of platelet/white clot formation
start with activated platelets end with platelet plug forms 1-4 mins after injury -
ANSWERactivated platelets secrete ADP->activation ofCOX pathway->phospholipase
2 mediated->thromboxane A2 production->further activation ofplatelets to area -
>platelet plug
coag pathways activated by extrinsic or intrisic pathways
describe common coag. pathway - ANSWERextrinsic or intrinsic pathway triggers....
activation of factor x->
conversion of prothrombin->
thrombin->
fibrinogen->
fibrin->
fibrin mesh clot
what point in common coag pathway does coumadin work? - ANSWERat the
conversion of prothrombin to thrombin
inhibits vitamin K
what point in common coag pathway does heparin work? - ANSWERthrombin to.
fibrinogen
inhibits thrombin
intrinsic coag pathway is stimulated by what - ANSWERvascular endothelial injury
like...
cell trauma-valve, IABP
sepsis
shock
ARDS
hypoxemia/acidemia
cardiopulmonary arrest
, extrinsic coag pathway is stimulated by what - ANSWERtissue injury and releases
tissue thromboplastin...
extensive trauma
OB emergencies
malignanceis
dissecting aortic aneurysm
extensive MI
patho of inhibition of clot formation/clot breakdown starting at clot/thrombin -
ANSWERthrombin->
plasminogen->
plasmin->
lysosomal enzymes->
splitting of fibrin and fibrinogen->
formation of fibrin split products FSPs
reversal of heparin? - ANSWERprotamine
reversal of warfarin/coumadin? - ANSWERvitmamin K
DIC is caused by what - ANSWERactivation of clotting -fibrinolytic system with
resultant consumption of clotting factors
lab values for DIC in primary DIC what do you see - ANSWERdecreased platelets,
fibrinogen, hematocrit
increased FSP-due to increased fibrinolysis
increased PT, PTT, INR, bleed time
lab values in DIC secondary - ANSWERincreased D dimer-assesses presence of clots
increased antithrombin 3
DIC is primarily a _ problem - ANSWERclotting
not bleeding
DIC is always _ to another problem - ANSWERsecondary
causes of DIC 4 categories and give examples
1. endothelial damage
2. release of tissue thromboplastin
3. factor x activation
4. micellaneous - ANSWER1. endothelial damage-sepsis, hypoxemia, shock, ARDS,
AAA, acidemia, CPR
2. release of tissue thromboplastin-extensive trauma, malignancies, OB emergencies,
dssecting aortic aneurysm
3. factor x activation-acute pancreatitis, livr disease
4. micellaneous-massive transfusions, PE, hemolytic anemia, fresh water drowning,
aspirin poisoning
