Test Bank Complete_ Understanding Pharmacology:
Essentials for Medication Safety 3rd Edition, (2023) By
M. Linda Workman & Linda A. LaCharity All Chapters 1-
29| Nine Units| Questions with Answers & Explanation
Absorption - ANSWERMovement of a drug from the outside of the body into the
blood stream.
Agonist - ANSWERAn extrinsic drug that activates the receptor site of a cell and
mimics the actions of naturally occurring drugs.
Antagonist - ANSWERAn extrinsic drug that blocks the receptor site of a cell,
preventing the naturally occurring substance from binding to the receptor.
Bioavailability - ANSWERThe percentage of a drug dose that actually reaches the
blood.
Black Box Warning - ANSWERA notice that a drug may produce serious or even life
threatening effects in some people in addition to its beneficial effects.
Cytoxic - ANSWERA drug action that is intended to kill a cell or organism.
Distribution - ANSWERThe extent that a drug absorbed into the bloodstream spreads
into the three body water components.
Duration of Action - ANSWERThe length of time a drug is present in the blood at or
above the level needed to produce an effect or response.
Extrinsic Drugs - ANSWERDrugs that are man made or derived from another species;
not made by the human body.
First pass loss - ANSWERRapid inactivation or elimination of oral drugs as a result of
liver metabolism.
Generic Name - ANSWERNational and international public drug name created by the
United States Adopted NamesCouncil to indicate the usual use or chemical
composition of a drug.
Half Life - ANSWERTime san needed for one half of a drug dose to be eliminated.
High Alert Drug - ANSWERA drug that has an increased risk of causing patient harm if
it is used in error.
, Loading Dose - ANSWERThe first dose of a drug that is larger than all subsequent
doses of the same drug; used when it takes more drug to reach steady state that it
does to maintain it.
Mechanism of Action - ANSWERExactly how, at the cellular level, a drug changes the
activity of a cell.
Minimum Effective
Concentration - ANSWERThe smallest amount of drug necessary in the blood or
target tissue to result in a measurable intended action.
Percutaneous Route - ANSWERMovement of a drug from the outside of the body to
the inside through the skin or mucous membranes.
Pharmacodynamics - ANSWERWays in which drugs work to change body function.
Pharmacokinetics - ANSWERHow the body changes drugs; drug metabolism.
Physiologic Effects - ANSWERThe change in body function as an income of the
mechanism of action off a drug.
Receptors - ANSWERPhysical place on or in a cell where a drug can bind and interact.
Sequestration - ANSWERThe trapping of drugs within certain body tissues, delaying
their elimination and extending their duration of action.
Steady State - ANSWERPoint at which drug elimination is balance with drug entry,
resulting in a constant effective blood level of the drug.
Target Tissue - ANSWERThe actual cells or tissues affected by the mechanism of
action or intended actions of a specific drug.
Transdermal - ANSWERType of percutaneous drug delivery in which the drug is
applied to the skin, passes through the skin and enters the bloodstream.
Vaporized - ANSWERChanging of a drug from a liquid form to a gas that can be
absorbed into the body by inhalation.
A plan to improve or prevent a health problem that includes the use of drugs. -
ANSWERDrug therapy.
What factors does drug therapy involve? - ANSWER1. Identifying the specific health
problem.
2. Determining what drug or drugs would be the best treatment for the problem.
3. Deciding the best delivery method and schedule.
4. Ensuring that the proper amount of the drug is given.
5. Helping the patient become an active participant in his or her drug therapy.
Essentials for Medication Safety 3rd Edition, (2023) By
M. Linda Workman & Linda A. LaCharity All Chapters 1-
29| Nine Units| Questions with Answers & Explanation
Absorption - ANSWERMovement of a drug from the outside of the body into the
blood stream.
Agonist - ANSWERAn extrinsic drug that activates the receptor site of a cell and
mimics the actions of naturally occurring drugs.
Antagonist - ANSWERAn extrinsic drug that blocks the receptor site of a cell,
preventing the naturally occurring substance from binding to the receptor.
Bioavailability - ANSWERThe percentage of a drug dose that actually reaches the
blood.
Black Box Warning - ANSWERA notice that a drug may produce serious or even life
threatening effects in some people in addition to its beneficial effects.
Cytoxic - ANSWERA drug action that is intended to kill a cell or organism.
Distribution - ANSWERThe extent that a drug absorbed into the bloodstream spreads
into the three body water components.
Duration of Action - ANSWERThe length of time a drug is present in the blood at or
above the level needed to produce an effect or response.
Extrinsic Drugs - ANSWERDrugs that are man made or derived from another species;
not made by the human body.
First pass loss - ANSWERRapid inactivation or elimination of oral drugs as a result of
liver metabolism.
Generic Name - ANSWERNational and international public drug name created by the
United States Adopted NamesCouncil to indicate the usual use or chemical
composition of a drug.
Half Life - ANSWERTime san needed for one half of a drug dose to be eliminated.
High Alert Drug - ANSWERA drug that has an increased risk of causing patient harm if
it is used in error.
, Loading Dose - ANSWERThe first dose of a drug that is larger than all subsequent
doses of the same drug; used when it takes more drug to reach steady state that it
does to maintain it.
Mechanism of Action - ANSWERExactly how, at the cellular level, a drug changes the
activity of a cell.
Minimum Effective
Concentration - ANSWERThe smallest amount of drug necessary in the blood or
target tissue to result in a measurable intended action.
Percutaneous Route - ANSWERMovement of a drug from the outside of the body to
the inside through the skin or mucous membranes.
Pharmacodynamics - ANSWERWays in which drugs work to change body function.
Pharmacokinetics - ANSWERHow the body changes drugs; drug metabolism.
Physiologic Effects - ANSWERThe change in body function as an income of the
mechanism of action off a drug.
Receptors - ANSWERPhysical place on or in a cell where a drug can bind and interact.
Sequestration - ANSWERThe trapping of drugs within certain body tissues, delaying
their elimination and extending their duration of action.
Steady State - ANSWERPoint at which drug elimination is balance with drug entry,
resulting in a constant effective blood level of the drug.
Target Tissue - ANSWERThe actual cells or tissues affected by the mechanism of
action or intended actions of a specific drug.
Transdermal - ANSWERType of percutaneous drug delivery in which the drug is
applied to the skin, passes through the skin and enters the bloodstream.
Vaporized - ANSWERChanging of a drug from a liquid form to a gas that can be
absorbed into the body by inhalation.
A plan to improve or prevent a health problem that includes the use of drugs. -
ANSWERDrug therapy.
What factors does drug therapy involve? - ANSWER1. Identifying the specific health
problem.
2. Determining what drug or drugs would be the best treatment for the problem.
3. Deciding the best delivery method and schedule.
4. Ensuring that the proper amount of the drug is given.
5. Helping the patient become an active participant in his or her drug therapy.
