Lipid Disorders
1. what is cholesterol?: a steroid needed by the body for production of vitamin D, bile acids, cortisol, estrogen,
progesterone, and testosterone
2. where do we get cholesterol from?: 75% made in the liver 25% from diet
3. what carries cholesterol?: The lipoprotein LDL
4. what are triglycerides?: 3 fatty acid molecules attached to glycerol- the back- bones of many fats
5. what carries triglycerides?: VLDL lipoproteins
6. what are the major lipoproteins?: chylomicrons HDL
LDL
VLDL
7. what do lipoproteins do?: transport cholesterol & triglycerides to tissues
8. what are chylomicrons?: triglyceride rich particles made by the intestines that carry dietary lipids to tissues & the
liver
9. what is LDL?: low density lipoprotein
10.where is LDL made?: liver
11.what is "bad cholesterol"?: LDL
12.what is VLDL?: very low density lipoprotein
13.where is VLDL made?: liver
14.what does VLDL do?: transports majority of TG
15.what does LDL do?: transports majority of cholesterol
16.what is HDL?: high density lipoprotein
17.where is HDL made?: liver
18.what does HDL do?: reverse cholesterol transport from tissues back to liver
19.what is the "good cholesterol"?: HDL
20.what is atherosclerosis?: buildup of cholesterol & fats leading to plaque forma- tion in arterial walls
21.what are high LDL and VLDL levels associated with?: increased risk for CAD & atherosclerosis
22.what is dyslipidemia?: abnormal amount of lipids in the blood
23.what are RF for dyslipidemia?: obesity sedentary
lifestyle
diet high in trans fats genetic
predisposition
24.how does dyslipidemia present?: MC asx
may have: xanthomas, xanthelasma, lipemia retinalis, triglyceride induced pancre- atitis
25.xanthoma:
1/
3
1. what is cholesterol?: a steroid needed by the body for production of vitamin D, bile acids, cortisol, estrogen,
progesterone, and testosterone
2. where do we get cholesterol from?: 75% made in the liver 25% from diet
3. what carries cholesterol?: The lipoprotein LDL
4. what are triglycerides?: 3 fatty acid molecules attached to glycerol- the back- bones of many fats
5. what carries triglycerides?: VLDL lipoproteins
6. what are the major lipoproteins?: chylomicrons HDL
LDL
VLDL
7. what do lipoproteins do?: transport cholesterol & triglycerides to tissues
8. what are chylomicrons?: triglyceride rich particles made by the intestines that carry dietary lipids to tissues & the
liver
9. what is LDL?: low density lipoprotein
10.where is LDL made?: liver
11.what is "bad cholesterol"?: LDL
12.what is VLDL?: very low density lipoprotein
13.where is VLDL made?: liver
14.what does VLDL do?: transports majority of TG
15.what does LDL do?: transports majority of cholesterol
16.what is HDL?: high density lipoprotein
17.where is HDL made?: liver
18.what does HDL do?: reverse cholesterol transport from tissues back to liver
19.what is the "good cholesterol"?: HDL
20.what is atherosclerosis?: buildup of cholesterol & fats leading to plaque forma- tion in arterial walls
21.what are high LDL and VLDL levels associated with?: increased risk for CAD & atherosclerosis
22.what is dyslipidemia?: abnormal amount of lipids in the blood
23.what are RF for dyslipidemia?: obesity sedentary
lifestyle
diet high in trans fats genetic
predisposition
24.how does dyslipidemia present?: MC asx
may have: xanthomas, xanthelasma, lipemia retinalis, triglyceride induced pancre- atitis
25.xanthoma:
1/
3
