QUESTIONS AND ANSWERS GRADED
A+
x Penicillinase-resistant penicillins - Correct answer.Oxacillin, nafcillin, dicloxacillin
broad spectrum penicillins - Correct answer.- ampicillin and amoxicillin
- good oral absorption (amoxicillin = excellent)
- broad spectrum (improved against gram negative organisms - e.coli, salmonella, shingella, H. Influenza,
H pylori, proteus)
How do penicillins and cephalosporins work? - Correct answer.By weakening the cell wall and promoting
lysis and death
Bactericidal drugs are - Correct answer.Directly lethal to bacteria at achievable concentrations
Why are narrow spectrum drugs preferred over broad spectrum antibiotics? - Correct answer.Broad
spectrum antibiotics do the most to facilitate emergence of resistance
How does bacterial resistance develop with penicillins? - Correct answer.-production of penicillin binding
proteins that have low affinity for penicillins
-inability of penicillins to reach their target
-inactivation of penicillins by bacterial enzymes
Mary is a 20 year old female you have diagnosed him with strep throat. She has had an anaphylactic
reaction to penicillin. Which of the following antibiotics is appropriate for Mary? - Correct
answer.Azithromycin
, What are penicillinases? - Correct answer.Beta-lactamases that act selectively on penicillins
The following are Penicillinases-resistant penicillins - Correct answer.Oxacillin, Dicloxacillin, Nafcillin
The following are broad spectrum penicillins (aminopenicillins) - Correct answer.Amoxicillin and
ampicillin
The following are extended-spectrum penicillins (antipseudomonal) - Correct answer.Ticarcillin and
Piperacillin
The following are beta-lactamase inhibitors - Correct answer.Sulbactam, tazobactam and clavilanic acid
Which cephalosporins are rarely used for active infections? - Correct answer.Second generation
Jack is taking Coumadin for his atrial fibrillation. Which of the following cephalosporins should not be
prescribed for jack? - Correct answer.Ceftriaxone and cefotetan
Third generation cephalosporins are good to treat - Correct answer.Meningitis
Fourth Generation Cephalosporins are good to treat? - Correct answer.Pneumonia
Vancomycin works by - Correct answer.Inhibiting Cell wall synthesis
Fluroquinolones work by - Correct answer.Disrupting DNA replication and cell revision
Jackson has community acquired pneumonia mycoplasma pneumonia's is suspected. Which of the
following is the best choice for treatment? - Correct answer.Doxycycline