HEMATOLOGY 3&4 Questions and Answers
1. T/F: if a disease is X linked recessive it typically effects mostly females since they only. have X
chromosomes.: False. it typically effects men since they only have ONE X chromosome. females have
two meaning they have a chance at the other X chromosome cancelling out disease.
2. What is Hemophilia A?: Factor VIII deficiency
in clotting factors you cannot fully activate Factor X without both Factor VII and VIII
*think of the slang word AIGHT to remember Hemophilia A is associated with EIGHT
3. What would the results of an APTT and PT test look like for a Hemophilia A or B patient?:
prolonged APTT
PT normal
for both
4. What is Hemophilia B common name?: Christmas disease
*are you ready for it to B CHRISTMAS
5. What is the main clinical finding in hemophilia patients?: increased risk of prolonged bleeding
from common injuries
severe cases=spontaneous bleeding
, HEMATOLOGY 3&4 Questions and Answers
*remember Hemophilia=blood loving
6. What are some of the common sites where bleeding is the most concerning in a Hemophilia
patient?: JOINT CAPSULES
SKELETAL MUSCLES GI
TRACT
BRAIN
7. What is typical treatment for Hemophilia?: routine supplementation for clotting factor levels;
EXTRA is given around surgical procedures or after trauma
8. T/F: There are only synthetic versions of Coagulation Factors V, VII and VIII.: False.
There are synthetic versions of ALL coagulation factors
9. What are oral manifestations in hemophilia patients?: patients might BLEED EVERY TIME
THEY BRUSH
-results in higher risk for caries and periodontal disease due to lack of oral hygiene
children BLEED after losing baby teeth
severe cases=spontaneous bleeding from oral tissues
, HEMATOLOGY 3&4 Questions and Answers
HEMARTHROSIS: bleeding into joint space=TMJ=RARE
10. What are some solutions you can offer your hemophilia patients in the dental setting?:
EXTRA SOFT/ SOFT bristled tooth brush for cleaning to minimize bleeding
EDUCATE against oral piercings
medicated MOUTHWASH to decrease oral disease AVOID
ASPIRIN/NSAIDS bc they affect platelet fx
MOUTHGUARDS: especially for contact sports
PRESCRIBE ACETAMINOPHEN as a pain reliever when needed
11. What is Von Willebrand's Disease?: INHERITED BLEEDING DISORDER Effects
MEN/WOMEN EQUALLY
12. What are the APTT and PT results of a vWF disease patient?: prolonged APTT
AND prolonged PT
due to resulting reduced factor VIII and failure in platelet-vessel wall interaction
13. What are the two main roles of vWF?: mediate platelet adhesion stabilizing
factor VIII
if there is a deficiency, neither one of these are happening, thus resulting in very similar clinical
signs to hemophilia
1. T/F: if a disease is X linked recessive it typically effects mostly females since they only. have X
chromosomes.: False. it typically effects men since they only have ONE X chromosome. females have
two meaning they have a chance at the other X chromosome cancelling out disease.
2. What is Hemophilia A?: Factor VIII deficiency
in clotting factors you cannot fully activate Factor X without both Factor VII and VIII
*think of the slang word AIGHT to remember Hemophilia A is associated with EIGHT
3. What would the results of an APTT and PT test look like for a Hemophilia A or B patient?:
prolonged APTT
PT normal
for both
4. What is Hemophilia B common name?: Christmas disease
*are you ready for it to B CHRISTMAS
5. What is the main clinical finding in hemophilia patients?: increased risk of prolonged bleeding
from common injuries
severe cases=spontaneous bleeding
, HEMATOLOGY 3&4 Questions and Answers
*remember Hemophilia=blood loving
6. What are some of the common sites where bleeding is the most concerning in a Hemophilia
patient?: JOINT CAPSULES
SKELETAL MUSCLES GI
TRACT
BRAIN
7. What is typical treatment for Hemophilia?: routine supplementation for clotting factor levels;
EXTRA is given around surgical procedures or after trauma
8. T/F: There are only synthetic versions of Coagulation Factors V, VII and VIII.: False.
There are synthetic versions of ALL coagulation factors
9. What are oral manifestations in hemophilia patients?: patients might BLEED EVERY TIME
THEY BRUSH
-results in higher risk for caries and periodontal disease due to lack of oral hygiene
children BLEED after losing baby teeth
severe cases=spontaneous bleeding from oral tissues
, HEMATOLOGY 3&4 Questions and Answers
HEMARTHROSIS: bleeding into joint space=TMJ=RARE
10. What are some solutions you can offer your hemophilia patients in the dental setting?:
EXTRA SOFT/ SOFT bristled tooth brush for cleaning to minimize bleeding
EDUCATE against oral piercings
medicated MOUTHWASH to decrease oral disease AVOID
ASPIRIN/NSAIDS bc they affect platelet fx
MOUTHGUARDS: especially for contact sports
PRESCRIBE ACETAMINOPHEN as a pain reliever when needed
11. What is Von Willebrand's Disease?: INHERITED BLEEDING DISORDER Effects
MEN/WOMEN EQUALLY
12. What are the APTT and PT results of a vWF disease patient?: prolonged APTT
AND prolonged PT
due to resulting reduced factor VIII and failure in platelet-vessel wall interaction
13. What are the two main roles of vWF?: mediate platelet adhesion stabilizing
factor VIII
if there is a deficiency, neither one of these are happening, thus resulting in very similar clinical
signs to hemophilia
