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BIOL4100: BRAIN RHYTHMS AND SLEEP EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED

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BIOL4100: BRAIN RHYTHMS AND SLEEP EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED Electroencephalogram Measures generalized activity in µV, requiring activation of many thousands of neurons activated together to generate signal with sufficient strength to record Electroencephalogram Signals Come from synaptic excitation of dendrites on cortical pyramidal neurons How Electroencephalogram Works Afferent axon releases glutamate, depolarizes neuron, making extracellular fluid more negative, and is based on comparison to nearby reference electrode Electroencephalogram Activity Must be synchronous EEG Rhythms Beta, alpha, theta, and delta Beta Rhythm Fastest, 14 Hz, activated cortex Alpha Rhythm 8-13 Hz, quiet waking state Theta Rhythm 4-7 Hz, occurs during some sleep stages Delta Rhythm Slowest, 4 Hz, large amplitude, deep sleep Source of Synchronous Rhythms Cued by a central clock or pacemaker or distribute timing function by mutually exciting or inhibiting one another Mammalian Source of Synchronous Rhythms Combination of both sources of rhythmic neuronal activity Simple Two-Neuron Oscillator Excitatory input is constant, E cell depolarizes and excites I cell, and I cells depolarizes and inhibits E cell Thalamus as a Pacemaker Cells contain voltage-gated ion channels allowing for rhythmic, self-sustaining discharge patterns even in the absence of external input, allowing cells to become synchronized 3 Potential Functions of Brain Rhythms Brain's way of disconnecting cortex from sensory input during sleep, neural rhythms coordinate activity between regions when awake, or just by-products which no purpose Mechanisms of Seizures Depend largely upon the type of seizure Behavioral Features of Seizures Associated largely with the location of seizure and pattern of seizure activity Generalized Seizures Involve most of the cortex and disrupt virtually all ongoing behavior during the seizure Absence Seizures Most frequent in childhood, ~ 30 sec of generalized 3 Hz EEG activity, and loss of consciousness

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BIOL4100: BRAIN RHYTHMS AND SLEEP EXAM QUESTIONS

AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED

Electroencephalogram

Measures generalized activity in µV, requiring activation of many thousands of neurons

activated together to generate signal with sufficient strength to record

Electroencephalogram Signals

Come from synaptic excitation of dendrites on cortical pyramidal neurons

How Electroencephalogram Works

Afferent axon releases glutamate, depolarizes neuron, making extracellular fluid more

negative, and is based on comparison to nearby reference electrode

Electroencephalogram Activity

Must be synchronous

EEG Rhythms

Beta, alpha, theta, and delta

Beta Rhythm

Fastest, > 14 Hz, activated cortex

Alpha Rhythm

8-13 Hz, quiet waking state

Theta Rhythm

4-7 Hz, occurs during some sleep stages

Delta Rhythm

Slowest, < 4 Hz, large amplitude, deep sleep

, Source of Synchronous Rhythms

Cued by a central clock or pacemaker or distribute timing function by mutually exciting

or inhibiting one another

Mammalian Source of Synchronous Rhythms

Combination of both sources of rhythmic neuronal activity

Simple Two-Neuron Oscillator

Excitatory input is constant, E cell depolarizes and excites I cell, and I cells depolarizes

and inhibits E cell

Thalamus as a Pacemaker

Cells contain voltage-gated ion channels allowing for rhythmic, self-sustaining discharge

patterns even in the absence of external input, allowing cells to become synchronized

3 Potential Functions of Brain Rhythms

Brain's way of disconnecting cortex from sensory input during sleep, neural rhythms

coordinate activity between regions when awake, or just by-products which no purpose

Mechanisms of Seizures

Depend largely upon the type of seizure

Behavioral Features of Seizures

Associated largely with the location of seizure and pattern of seizure activity

Generalized Seizures

Involve most of the cortex and disrupt virtually all ongoing behavior during the seizure

Absence Seizures

Most frequent in childhood, ~ 30 sec of generalized 3 Hz EEG activity, and loss of

consciousness

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