PROCTORED ACTUAL EXAM TEST BANK 200 QUESTIONS AND CORRECT
DETAILED ANSWERS WITH RATIONALES|ALREADY GRADED A+
Barrier of this type of
absorption includes
passing through the Oral
layer of epithelial cells
that line the GI Tract
Absorption pattern for
this route varies greatly
due to stability and
solubility of the Oral
medication, GI pH, and
presence of food in the
stomach
Presence of stool may
affect the absorption of Rectal
this route
Which type of
absorption route has
no barriers, and Intravenous
reaches the blood in its
entirety?
, Absorption,
What are the phases of
Distribution,
pharmacokinetics?
Metabolism, Excretion
What phase of
pharmacokinetics is
the transportation of Distribution
medications to sites of
action by bodily fluids?
Circulation,
What factors affect
Permeability of the cell
distribution of
membrane, Plasma
medications?
protein binding
Primary: Liver
Where does most
metabolism of a
medication occur?
Where else can it Secondary: Kidneys,
occur? Intestines, Lungs, Blood
Generally as the body Declines with age, older
ages, what happens to adults require smaller
medication doses to avoid
metabolism? How does medication
this affect the dose? accumulation
Occurs when the liver First Pass Effect
, inactivates the
medication and results
in nonenteral
administration
Primary: Kidneys
Where does excretion
of medications
primarily occur? Secondary: Liver, Lungs,
Secondarily? Intestines, Exocrine
Glands
To regulate medication
What is the goal of to maintain between
medication dosing? MEC and toxic
concentration.
High Therapeutic Index
have a wide safety
margin.
Which medications are
considered more safe?
High TI or Low TI? Low Therapeutic index
require close
monitoring of serum
medication levels
, Refers to the time it
takes for the
Half Life
medication in the drop
to drop by 50%
If there is liver or
kidney disfunction
Increases
what happens to half
life?
What is the interaction
between medications
and target cells, body Pharmacodynamics
systems, and organs to
produce effects?
Which type of
medications bind to or
Agonists, morphine
mimic receptors? And
what is an example?
What type of
Antagonists, losartan
medications block
(angiotensin II receptor
receptors? What is an
blocker)
example?
Which type of Partial agonists,
medications act as nalbuphine (antagonists
both agonists or against mu receptors,