WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
hormone action
Homeostasis is often an interplay between brain and body via ___
Amines
__ are derived from amino acids
Amines
Peptides and proteins
Steroids
Three major chemical classes of hormones are:
single
Amine is derived from a __ amino acids
inactive
Is Proinsulin active or inactive?
Liver
The __ is the major organ of hormone metabolism
Half-life
Time to clear half of the hormone from circulation
Peptides
__ = short proteins
Hydrophobic and Lipophilic
, Steroid hormones are __ and __
Cholesterol
__ is building block for steroid hormones
binding proteins
Lipophilic and Hydrophobic hormones tend to be transported through the blood via ___
inactive
Free, active hormone continues to signal until its metabolized to an ___ form
receptors
The ability of a cell to respond to a hormone depends upon the presence of __ for that
hormone on or in the target cell
up-regulation
An increase in the number of receptors for a hormone
down-regulation
A decrease in the number of receptors for a hormone
GPCR
__ sits at membrane, connects to G protein
G protein
Can be stimulatory (Gs, Gq) or inhibitory (Gi) on an "effector enzyme"
Effector enzyme
Generates a "second messenger", such as cyclic AMP or calcium
Kinase
Activated by a second messenger. Attaches phosphate groups to proteins, which alters
their function, thereby altering cellular physiology