Advanced Biochemistry Final Exam
Questions and Answers 100% Solved
N5,N10-methylene-THF - ✔✔directly used to convert uracils to thymines
5-methyl uracil - ✔✔N5,N10-methylene-THF methylates where
N5-methyl-THF - ✔✔used to remethylate homocysteine
folic acid - ✔✔typical nature of the supplement found in USA wheat flour to
provide methylated forms of THF.
DHF - ✔✔normal substrate for the enzyme inhibited by methotrexate (an
early chemotherapeutic agent).
Trimethoprim - ✔✔inhibitor of DHF reductase found in a widely distributed
"sulfa drug"
Acyclovir - ✔✔toxic agent avidly activated by herpes thymine kinase
Replication - ✔✔what process does acyclovir inhibit
Doxyclycline - ✔✔inhibitor of A site occupancy by aminoacyl-tRNAs?
concentrated - ✔✔Doxycline affects bacteria because it is?
1
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
, increases Uracils in DNA because you cannot change from Uracils to
Thymines which will ultimately cause apoptosis due to too much gaps in
the DNA - ✔✔lack of folic acid
Takes the Uracils out of the DNA in order for repair endonuclease to "fix"
the DNA - ✔✔Uracil DNA glycosylase
activates apoptosis - ✔✔double-strand and single- strand breaks in DNA
caused by damage
activates expression of Nox2 which produces O radicals which activate s-
nitrosohomocysteine - ✔✔homocysteine activates?
Glutathione - ✔✔cysteine is important in making
rrpsy - ✔✔recognition sequence for pka
bZIP proteins - ✔✔Basic and Leucine zipper (CREB)
CREB - ✔✔cAMP response element binding protein
transcription factor
histone acetyltransferase (HAT) - ✔✔unwraps the DNA (acetylation)
CARM1/PRMT - ✔✔Methylates CBP
Flavin - ✔✔
Ribose - ✔✔What is flavin attached to?
2
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
Questions and Answers 100% Solved
N5,N10-methylene-THF - ✔✔directly used to convert uracils to thymines
5-methyl uracil - ✔✔N5,N10-methylene-THF methylates where
N5-methyl-THF - ✔✔used to remethylate homocysteine
folic acid - ✔✔typical nature of the supplement found in USA wheat flour to
provide methylated forms of THF.
DHF - ✔✔normal substrate for the enzyme inhibited by methotrexate (an
early chemotherapeutic agent).
Trimethoprim - ✔✔inhibitor of DHF reductase found in a widely distributed
"sulfa drug"
Acyclovir - ✔✔toxic agent avidly activated by herpes thymine kinase
Replication - ✔✔what process does acyclovir inhibit
Doxyclycline - ✔✔inhibitor of A site occupancy by aminoacyl-tRNAs?
concentrated - ✔✔Doxycline affects bacteria because it is?
1
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
, increases Uracils in DNA because you cannot change from Uracils to
Thymines which will ultimately cause apoptosis due to too much gaps in
the DNA - ✔✔lack of folic acid
Takes the Uracils out of the DNA in order for repair endonuclease to "fix"
the DNA - ✔✔Uracil DNA glycosylase
activates apoptosis - ✔✔double-strand and single- strand breaks in DNA
caused by damage
activates expression of Nox2 which produces O radicals which activate s-
nitrosohomocysteine - ✔✔homocysteine activates?
Glutathione - ✔✔cysteine is important in making
rrpsy - ✔✔recognition sequence for pka
bZIP proteins - ✔✔Basic and Leucine zipper (CREB)
CREB - ✔✔cAMP response element binding protein
transcription factor
histone acetyltransferase (HAT) - ✔✔unwraps the DNA (acetylation)
CARM1/PRMT - ✔✔Methylates CBP
Flavin - ✔✔
Ribose - ✔✔What is flavin attached to?
2
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
