MEDICAL PHYSIOLOGY AND PHARMACOLOGY
FINAL EXAM FOR GRADUATION NEWEST ACTUAL
EXAM COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS)
|ALREADY GRADED A+
which definition best describes a lead compound - (answers)the first compound
discovered to have the desired activity
which method of discovering a drug is generally the least expensive -
(answers)molecular docking
what is the name of the process that involves step-wise alteration of a drug to
improve its properties - (answers)structure activity relationship
what was the estimated research and development expenses of pharma in 2016 -
(answers)60 billion
which branch of pharmacology studies the effect of the body on drugs -
(answers)pharmacokinetics
which branch of pharmacology studies how patients respond differently to drugs -
(answers)pharmacogenetics
which branch of pharmacology studies the desired effect of drugs on the body,
usually at the molecular level - (answers)pharmacodynamics
,which branch of pharmacology studies adverse effects of drugs on the body -
(answers)toxicology
which branch of pharmacology does excretion fall under -
(answers)pharmacokinetics
which is the chemical name for a popular OTC pain killer - (answers)N-acetyl-
para-aminophenol
which stage of translational research is the first to utilize a FDA approved drug -
(answers)T3
the transition between which two phases of translational research involves
switching from controlled settings real-world setting - (answers)T2-T3
which type of drug is most likely to be given orally - (answers)small molecule
overnight contact lenses are considered ? medical devices - (answers)class III
which term describes the process of taking a piece of humor tumor from a patient
and placing it under the skin of a mouse in order to do pre-clinical testing -
(answers)patient-derived xenograft
in order to do a clinical trial in humans, IRB approval must be obtained. From
which regulatory body must approval be obtained in order to carry out a similar
study in rats? - (answers)IACUC
,gaining information on which of the following is the primary purpose of a Phase I
clinical trial - (answers)treatment safety
which of the following requires direct action by a patient (or their guardian) before
they can be enrolled in a phase I clinical trial - (answers)informed consent
in which type of clinical trial is a MTD most likely to be determined -
(answers)phase 1
what government agency regulates phase I clinical trials in the US -
(answers)FDA
a clinical trial for the use of a new pain killer in terminal cancer patients who have
been admitted to hospice would be considered what type of clinical trial -
(answers)quality of life trial
how many groups of patients would be required for a placebo-controlled factorial
trial to test combinations of three drugs - (answers)8
in which type of clinical trial is every patient guaranteed to receive active drug -
(answers)cross-over trial
exclusion criteria for a clinical trial for a new therapy for pediatric leukemia -
(answers)patient is greater than 12 years old
, the most common target of drugs is - (answers)receptors
Gleevac targets - (answers)enzymes
a diabetic receives an injection of insulin. Once the insulin reaches the pancreas,
how long do you expect it to take before a response can be measured -
(answers)minutes
a dose of agonist occupies 30% of receptors and gives an effect of 50. According
to the occupancy theory, what effect would you expect from a dose that occupies
90% of receptors - (answers)150
most drugs bind in such a way that it is reversible without a chemical reaction.
These drugs must therefore lack which type of bond with their targets -
(answers)covalent
drug A requires 15 micromolar to reach 50% of its maximum response while drug
B requires 50 micromolar to reach 50% of its maximum response, which drug is
more potent - (answers)drug A
drug A requires 15 micromolar to reach 50% of its maximum response while drug
B requires 50 micromolar to reach 50% of its maximum response, which drug is
more effective - (answers)cannot tell
which term describes a molecule that produces an effect when binding a receptor
but is incapable of inducing 100% effect - (answers)partial agonist
FINAL EXAM FOR GRADUATION NEWEST ACTUAL
EXAM COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS)
|ALREADY GRADED A+
which definition best describes a lead compound - (answers)the first compound
discovered to have the desired activity
which method of discovering a drug is generally the least expensive -
(answers)molecular docking
what is the name of the process that involves step-wise alteration of a drug to
improve its properties - (answers)structure activity relationship
what was the estimated research and development expenses of pharma in 2016 -
(answers)60 billion
which branch of pharmacology studies the effect of the body on drugs -
(answers)pharmacokinetics
which branch of pharmacology studies how patients respond differently to drugs -
(answers)pharmacogenetics
which branch of pharmacology studies the desired effect of drugs on the body,
usually at the molecular level - (answers)pharmacodynamics
,which branch of pharmacology studies adverse effects of drugs on the body -
(answers)toxicology
which branch of pharmacology does excretion fall under -
(answers)pharmacokinetics
which is the chemical name for a popular OTC pain killer - (answers)N-acetyl-
para-aminophenol
which stage of translational research is the first to utilize a FDA approved drug -
(answers)T3
the transition between which two phases of translational research involves
switching from controlled settings real-world setting - (answers)T2-T3
which type of drug is most likely to be given orally - (answers)small molecule
overnight contact lenses are considered ? medical devices - (answers)class III
which term describes the process of taking a piece of humor tumor from a patient
and placing it under the skin of a mouse in order to do pre-clinical testing -
(answers)patient-derived xenograft
in order to do a clinical trial in humans, IRB approval must be obtained. From
which regulatory body must approval be obtained in order to carry out a similar
study in rats? - (answers)IACUC
,gaining information on which of the following is the primary purpose of a Phase I
clinical trial - (answers)treatment safety
which of the following requires direct action by a patient (or their guardian) before
they can be enrolled in a phase I clinical trial - (answers)informed consent
in which type of clinical trial is a MTD most likely to be determined -
(answers)phase 1
what government agency regulates phase I clinical trials in the US -
(answers)FDA
a clinical trial for the use of a new pain killer in terminal cancer patients who have
been admitted to hospice would be considered what type of clinical trial -
(answers)quality of life trial
how many groups of patients would be required for a placebo-controlled factorial
trial to test combinations of three drugs - (answers)8
in which type of clinical trial is every patient guaranteed to receive active drug -
(answers)cross-over trial
exclusion criteria for a clinical trial for a new therapy for pediatric leukemia -
(answers)patient is greater than 12 years old
, the most common target of drugs is - (answers)receptors
Gleevac targets - (answers)enzymes
a diabetic receives an injection of insulin. Once the insulin reaches the pancreas,
how long do you expect it to take before a response can be measured -
(answers)minutes
a dose of agonist occupies 30% of receptors and gives an effect of 50. According
to the occupancy theory, what effect would you expect from a dose that occupies
90% of receptors - (answers)150
most drugs bind in such a way that it is reversible without a chemical reaction.
These drugs must therefore lack which type of bond with their targets -
(answers)covalent
drug A requires 15 micromolar to reach 50% of its maximum response while drug
B requires 50 micromolar to reach 50% of its maximum response, which drug is
more potent - (answers)drug A
drug A requires 15 micromolar to reach 50% of its maximum response while drug
B requires 50 micromolar to reach 50% of its maximum response, which drug is
more effective - (answers)cannot tell
which term describes a molecule that produces an effect when binding a receptor
but is incapable of inducing 100% effect - (answers)partial agonist
