Walden 6630 Psychopharmacology Midterm exam
Study Guide with correct verified answers. Latest
2025
1. Serotonin regulates: Mood, emotion, feeding, and reproductive behavior
2. This class of antidepressants binds to presynaptic SERT and inhibits them from
reuptake of serotonin to increase levels in the synaptic cleft to bind with
postsysnaptic 5HT2 receptors: SSRIs
3. First line therapy for MDD due to milder side effect profiles: SSRIs
4. Six Common SSRIs: citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
5. Onset of therapeutic benefit from SSRIs: 4-6 weeks
6. In addition to MDD, SSRIs also treat: Chronic Anxiety, PTSD, OCD, and eating
disorders (bulimia)
7. Five Common side effects of SSRIs include: Anxiety, insomnia, GI distress, sexual
dysfunction (ED), SIADH
8. Severe side effect of SSRIs in children/adolescents under age 25 years old:
suicidal ideation
9. Life threatening adverse effect of SSRIs, especially when used in combination
with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.): Serotonin
, .
Syndrome
10. Excess accumulation of serotonin resulting in overstimulation of the nervous
system: Serotonin Syndrome
11. Seven symptoms of Serotonin Syndrome: Flushing, hyperthermia, agitation,
muscle rigidity, seizure, coma, HYPERreflexia
12. The treatment for serotonin syndrome: Cyproheptadine (5-HT2 receptor
antagonist)
13. Cyproheptadine treats serotonin syndrome by: blocking 5-HT2 receptors
(serotonin antagonist)
14. When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal
include: Irritability, headaches, and insomnia
15. Medicine specific side effect of citalopram: Prolonged QT interval (normal=0.4.-
0.44 seconds)
16. This SSRI is pregnancy category D due to associations with congenital heart
defects: Paroxetine
17. All SSRIs but paroxetine (D) are pregnancy category: C
18. Three SSRIs that are inhibitors of Cytochrome P450 enzymes: fluoxetine,
fluvoxamine, and paroxetine
, .
19. Five common SNRIs include: duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
20. This antidepressant class of medications works by binding to presynaptic SERT
and NET to inhibit them from reuptake of serotonin and norepinephrine to
increase their levels in the synaptic cleft: SNRIs
21 In addition to MDD SNRIs treat: Anxiety and neuropathic pain (peripheral
neuropathy)
22. Medication specific indications of duloxetine:: urinary incontinence and
Fibromyalgia
23. Medication specific indications of venlafaxine:: social anxiety, panic disorders,
PTSD, OCD, postmenopausal hot flashes
24. Six common side effects of SNRIs include:: Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches
25. Severe side effect of SNRIs in children/adolescents under age 25 years old::
suicidal ideation
26. Life threatening adverse effect of SNRIs, especially when used in combination
with other serotonergic drugs:: Serotonin Syndrome
27. This SNRI is an inhibitor of Cytochrome P450 enzymes:: venlafaxine
28. This SNRI is hepatotoxic:: duloxetine
Study Guide with correct verified answers. Latest
2025
1. Serotonin regulates: Mood, emotion, feeding, and reproductive behavior
2. This class of antidepressants binds to presynaptic SERT and inhibits them from
reuptake of serotonin to increase levels in the synaptic cleft to bind with
postsysnaptic 5HT2 receptors: SSRIs
3. First line therapy for MDD due to milder side effect profiles: SSRIs
4. Six Common SSRIs: citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
5. Onset of therapeutic benefit from SSRIs: 4-6 weeks
6. In addition to MDD, SSRIs also treat: Chronic Anxiety, PTSD, OCD, and eating
disorders (bulimia)
7. Five Common side effects of SSRIs include: Anxiety, insomnia, GI distress, sexual
dysfunction (ED), SIADH
8. Severe side effect of SSRIs in children/adolescents under age 25 years old:
suicidal ideation
9. Life threatening adverse effect of SSRIs, especially when used in combination
with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.): Serotonin
, .
Syndrome
10. Excess accumulation of serotonin resulting in overstimulation of the nervous
system: Serotonin Syndrome
11. Seven symptoms of Serotonin Syndrome: Flushing, hyperthermia, agitation,
muscle rigidity, seizure, coma, HYPERreflexia
12. The treatment for serotonin syndrome: Cyproheptadine (5-HT2 receptor
antagonist)
13. Cyproheptadine treats serotonin syndrome by: blocking 5-HT2 receptors
(serotonin antagonist)
14. When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal
include: Irritability, headaches, and insomnia
15. Medicine specific side effect of citalopram: Prolonged QT interval (normal=0.4.-
0.44 seconds)
16. This SSRI is pregnancy category D due to associations with congenital heart
defects: Paroxetine
17. All SSRIs but paroxetine (D) are pregnancy category: C
18. Three SSRIs that are inhibitors of Cytochrome P450 enzymes: fluoxetine,
fluvoxamine, and paroxetine
, .
19. Five common SNRIs include: duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
20. This antidepressant class of medications works by binding to presynaptic SERT
and NET to inhibit them from reuptake of serotonin and norepinephrine to
increase their levels in the synaptic cleft: SNRIs
21 In addition to MDD SNRIs treat: Anxiety and neuropathic pain (peripheral
neuropathy)
22. Medication specific indications of duloxetine:: urinary incontinence and
Fibromyalgia
23. Medication specific indications of venlafaxine:: social anxiety, panic disorders,
PTSD, OCD, postmenopausal hot flashes
24. Six common side effects of SNRIs include:: Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches
25. Severe side effect of SNRIs in children/adolescents under age 25 years old::
suicidal ideation
26. Life threatening adverse effect of SNRIs, especially when used in combination
with other serotonergic drugs:: Serotonin Syndrome
27. This SNRI is an inhibitor of Cytochrome P450 enzymes:: venlafaxine
28. This SNRI is hepatotoxic:: duloxetine
