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MODERNBLOODBANKING
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DENISE M. HARMENING
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, Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
j j j j j j j j j j
MultiplejChoice
Identifyjthejchoicejthatjbestjcompletesjthejstatementjorjanswersjthejquestion.
1.j j Whichjmetabolicjpathwayjisjresponsiblejforjgeneratingj90%jofjthejATPjforjthejRBC?
a. Pentosejphosphatejshunt c. Glycolysis
b. Luebering-Rapoportjshunt d.j j Methemoglobinjreductase
2.j Ajunitjofjbloodjwasjreturnedjtojthejbloodjbankjbeforejitjwasjspiked.jApparentlyjthejpatient’sjIVjfailed.jThej
unitjofjbloodjwasjoutsidejthejbloodjbankjforj35jminutes.jWhichjofjthejstatementsjbelowjisjmostjaccurate?
a. Thejunitjofjbloodjshouldjbejdiscardedjimmediately.
b. Thejunitjofjbloodjcanjbejreturnedjtojinventory.
c. Thejunitjofjbloodjmustjbejtransfusedjwithinj4jhoursjorjbejdiscardedjatjthejendjofjthatjtime.
d. Thejunitjofjbloodjmustjbejtransfusedjwithj24jhours.
3.j j Whatjisjthejaveragejdiameterjofjajplatelet?
a. 5jtoj10jµm c. 1jtoj2jµm
b. 2jtoj4jµm d.j j 4jtoj6jµm
4.j Injthejnormaljhemoglobin-
oxygenjdissociationjcurve,jwhatjpercentagejofjoxygenjisjreleasedjtojthejtissuesjwhenjPO2javeragesj40jmmjHg
?
a. 75% c. 100%
b. 25% d.j j 50%
5.j j Whatjfactorsjarejknownjtojinfluencejplateletjmetabolismjandjfunction?
a. Storagejtemperature c. Plateletjcount
b. InitialjpH d.j j Alljofjthejabove
6.j Whichjofjthejfollowingjredjbloodjcelljmorphologiesjmayjbejpresentjonjthejperipheraljbloodjsmearjasjajresultj
ofjlossjofjRBCjmembrane?
a. Spherocytes c. Burrjcells
b. Targetjcells d.j j Schistocytes
7.j j Whatjdoesjthejtermjautologousjtransfusionjreferjto?
a. Ajparentjdonatingjbloodjforjhisjorjherjchild
b. Anjindividualjdonatingjbloodjforjajfriend
c. Anjindividualjdonatingjbloodjforjajrelative
d. Anjindividualjdonatingjbloodjforjhisjorjherjownjtransfusion
8.j j Whatjisjthejprimaryjfunctionjofjhemoglobin?
a. Ironjmetabolism c. Oxygenjtransport
b. Porphyrinjsynthesis d.j j Signaljtransduction
9.j j Alljofjthejfollowingjareasjofjredjbloodjcelljbiologyjarejcrucialjforjnormaljerythrocytejsurvivalj except:
a. Cellularjmetabolism. c. SitejofjthejABOjantigenjattachment.
b. RBCjmembrane. d.j j Hemoglobinjstructure.
Thisjstudyjsourcejwasjdownloadedjbyj100000826342158jfromjCourseHero.comjonj09-15-2021j17:54:15jGMTj-05:00
https://www.coursehero.com/file/25537437/ch01rtf/
, j 10.j j WhatjisjthejcorrectjbiochemicaljcompositionjofjthejRBCjmembrane?
a. 52%jprotein,j40%jlipid,j8%jcarbohydrate
b. 40%jprotein,j8%jlipid,j52%jcarbohydrate
c. 8%jprotein,j52%jlipid,j40%jcarbohydrate
d. 8%jlipid,j40%jcarbohydrate,j52%jprotein
j 11.j j Alljofjthejfollowingjbiochemicaljchangesjarejassociatedjwithjlossjofjredjbloodjcelljviabilityjuponjstorage
except:
a. DecreasedjpH. c. IncreasedjATPjlevel.
b. Lossjofjredjbloodjcelljfunction. d.j j Decreasedjglucosejconsumption.
j 12.j j Whichjredjbloodjcelljpreservativejhasjajstoragejtimejofj35jdays?
a. ACD c. AS-1
b. CPDA-1 d.j j CPD
j 13.j j ThejRBCjmembranejisjrelativelyjpermeablejtojalljofjthejfollowingj except:
a. Chloride. c. Bicarbonate.
b. Sodium. d.j j Water.
j 14.j Whatjpercentagejofjplateletsjisjsequesteredjinjthejspleenjasjfunctionaljreservejafterjbeingjreleasedjfromjthejbonej
marrow?
a. 30% c. 10%
b. 50% d.j j 25%
j 15.j Whatjisjthejmajorjbiochemicaljconsiderationjinjplateletjstorage?
a. Glucosejmetabolism c. Productionjofjcarbonjdioxide
b. Oxygenjsupply d.j j RegulationjofjpH
j 16.j Whatjwouldjthejhemoglobin-
oxygenjdissociationjcurvejdepictjinjajpatientjexhibitingjclinicaljsignsjofjalkalosis?
a. Normal c. Shiftjtojthejright
b. Shiftjtojthejleft d.j j Nonejofjthejabove
j 17.j j Namejthejmainjlipidjcomponentsjofjajredjbloodjcelljmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.j j GlycophorinjA
j 18.j j ThejABOjbloodjgroupsjwerejdiscoveredjinj1901jbyjwhom?
a. CharlesjDrew c. LoutitjandjMollison
b. KarljLandsteiner d.j j EdwardjLindeman
j 19.j Ajstandingjorderjofjplateletsjwasjshippedjtojyourjfacilityjbyjyourjsupplier.jItjwasjinadvertentlyjleftjinjthejcornerjofj
thejdepartmentjuntiljdiscoveredj36jhoursjlater.jWhatjwouldjthejappropriatejactionjbejforjthejbloodjbanker?
a. Ifjthejtemperaturejinjthejboxjwasj22j+/-
j2°CjandjthejplateletjswirljseemedjOK,jitjwouldjbejOKjtojacceptjthejunitjintojinventory.
b. Thejplateletsjhavejfallenjoutsidejthejsupplier’sjqualityjassurance.jThejunitjshouldjbe
discardedjbecausejthejpHjhasjprobablyjdroppedjtoojlowjandjplateletjactivationjhasjbeenjcompromised
.
c. Ifjthejtemperaturejwasj1°Cjtoj6°CjandjthejplateletjswirljseemedjOK,jitjwouldjbejOKjto
Thisjstudyjsourcejwasjdownloadedjbyj100000826342158jfromjCourseHero.comjonj09-15-2021j17:54:15jGMTj-05:00
https://www.coursehero.com/file/25537437/ch01rtf/