TEST BANK b
Tietz Fundamentals Of
b b
CLINICAL CHEMISTRY AND
b b b
MOLECULAR DIAGNOSTICS b
7th Edition By Carl A. Burtis
b b b b b
TEST BANK b
,TietzbFundamentalsbofbClinicalbChemistrybandbMolecularbDiagnosticsb7thb EditionbTestbBank
Tablebofbcontents:
I.bPrinciplesbOfbLaboratorybMedicine
Chapterb1.bClinicalbChemistry,bMolecularbDiagnostics,bandbLaboratorybMedicine
Chapterb2.bSelectionbandbAnalyticalbEvaluationbofbMethodsb—bWithbStatisticalbTechniques
Chapterb3.bClinicalbEvaluationbofbMethods
Chapterb4.bEvidence-BasedbLaboratorybMedicine
Chapterb5.bEstablishmentbandbUsebofbReferencebValues
Chapterb6.bSpecimenbCollection,bProcessing,bandbOtherbPreanalyticalbVariables
Chapterb7.bQualitybManagement
II.bAnalyticalbTechniquesbAndbInstrumentation
Chapterb8.bPrinciplesbofbBasicbTechniquesbandbLaboratorybSafety
Chapterb9.bOpticalbTechniques
Chapterb10.bElectrochemistrybandbChemicalbSensors
Chapterb11.bElectrophoresis
Chapterb12.bChromatography
Chapterb13.bMassbSpectrometry
Chapterb14.bEnzymebandbRatebAnalyses
Chapterb15.bImmunochemicalbTechniques
Chapterb16bAutomation
Chapterb17.bPoint-of-CarebInstrumentation
III.b Analytes
Chapterb18.bAminobAcids,bPeptides,bandbProteins
Chapterb19.bSerumbEnzymes
Chapterb20.bTumorbMarkersbandbCancerbGenes
Chapterb21.bKidneybFunctionbTestsb—bCreatinine,bGFR,bUrea,bandbUricbAcid
Chapterb22.bCarbohydrates
Chapterb23.bLipids,bLipoproteins,bApolipoproteins,bandbOtherbCardiacbRiskbFactors
Chapterb24.bElectrolytesbandbBloodbGases
Chapterb25.bHormones
Chapterb26.b CatecholaminesbandbSerotonin
Chapterb27.b Vitamins,bTracebElements,bNutritionalbAssessment
Chapterb28.bHemoglobin,bIron,bandbBilirubin
Chapterb29.bPorphyrinsbandbPorphyrias
Chapterb30.bTherapeuticbDrugsbandbTheirbManagement
Chapterb31.bClinicalbToxicology
Chapterb32.b ToxicbMetals
IV.b Pathophysiology
Chapterb33.bDiabetes
,Chapterb34.b CardiovascularbDisease
Chapterb35.bKidneybDisease
Chapterb36.b PhysiologybandbDisordersbofbWater,bElectrolyte,bandbAcid-BasebMetabolism
Chapterb37.bbLiverbDisease
Chapterb38.b GastrointestinalbandbPancreaticbDiseases
Chapterb39.b DisordersbofbBonebandbMineralbMetabolism
Chapterb40.b DisordersbofbthebPituitarybGland
Chapterb41.b DisordersbofbthebAdrenalbCortex
Chapterb42.b ThyroidbDisorders
Chapterb43.b Reproduction-RelatedbDisorders
Chapterb44.bbPregnancybandbPrenatalbTesting
Chapterb45.b NewbornbScreeningbandb InbornbErrorsbofbMetabolism
Chapterb46.bPharmacogenetics
V.b MolecularbDiagnostics
Chapterb47.bPrinciplesbofbMolecularbBiology
Chapterb48.bNucleicbAcidbTechniquesbandbApplications
Chapterb49.bGenomesbandbNucleicbAcidbAlterations
, TietzbFundamentalsbofbClinicalbChemistrybandbMolecularDiagnostics,b7ebBurtisbTestbBank
Chapterb01:bClinicalbChemistry,bMolecularbDiagnostics,bandbLaboratorybMedicineTestb
Bank
MULTIPLEbCHOICE
1. Anbindividualbworkingbinbabclinicalbchemistryblaboratorybisbmarriedbtobabsalesbrepresentativebw
hobworksbforbabcompanybthatbsellsbchemistryblaboratorybsupplies.bWhenbtheblaboratorybmanage
rbrequestsbablistbofbneededbsupplies,bcostbofbsupplies,bandbvendors,bthisbindividualbonlybrecomme
ndsbthebspouse’sbcompanybasbthebvendor.bThisbisbconsideredbtobbeba(n):
a. accountingbissue.
b. possiblebconflictbofbinterest.
c. maintenancebofbconfidentialitybissue.
d. problembwithbresourceballocation.
ANS:b B
Concernbhasbbeenbraisedboverbthebinterrelationshipsbbetweenbpractitionersbinbthebmedicalbfieldba
ndbcommercialbsuppliersbofbdrugs,bdevices,bequipment,betc.,btobthebmedicalbprofession.
Similarly,brelationshipsbhavebbeenbscrutinizedbbetweenbclinicalblaboratoriansbandbmanufacturer
sbandbprovidersbofbdiagnosticbequipmentbandbsupplies.bThesebconcernsbledbthebNationalbInstitute
sbofbHealthb(NIH)binb1995btobrequirebofficialbinstitutionalbreviewbofbfinancialbdisclosurebbybresea
rchersbandbmanagementbofbsituationsbinbwhichbdisclosurebindicatesbpotentialbconflictsbofbinterest.
DIF: 1 REF:bbbPageb4-5 OBJ:b 6b|b7
2. Abpatientbvisitsbherbphysicianbstatingbthatbherbprescribedbpainkillerbisbnotbworkingbtobreducebt
hebpainbfollowingbherbrecentbsurgery.bAbfriendbofbthebpatientbclaimsbthatbthebsamebpainkillerb“
workedbwonders”btobreducebherbpainbafterbthebsamebsurgery.bThebphysicianbstatesbthatbthebdiff
erencebinbthebeffectbofbthebdrugbmightbbebcausedbby
,bwhichbisbstudiedbinbpharmacogenetics.
a. epidemiology
b. anbinheritedbdisease
c. abconflictbofbinterest
d. abgeneticbvariationbinbdrug-metabolizingbenzymes
ANS:b D
Pharmacogeneticsbisbthebstudybofbthebgeneticbvariationbofbdrugbmetabolismbbetweenbi
ndividuals.
DIF: 1 REF:bbbPageb3 OBJ:b 1
3. Johnbworksbinbabmolecularbdiagnosticsblaboratorybandbreceivesbabbloodbsamplebthatbhasbthebn
amebofbabclosebfriendbprintedbonbthebbar-
codedblabel.bThebgeneticbtestbthatbisborderedbonbthebfriend’sbsamplebwouldbprovidebdiagnosticb
informationbaboutbabdisorderbthatbhasbabpoorbprognosis,bandbthebtestbisbusuallybperformedbbybJ
ohn.bHebasksbabfellowbemployeebtobanalyzebthebsamplebforbhimbandbnotbdivulgebthebresults.bTh
isbethicalbissuebconcerns:
a. confidentialitybofbpatientbgeneticbandbmedicalbinformation.
b. abconflictbofbinterest.
c. resourceballocation.
d. diagnosticbaccuracy.
Tietz Fundamentals Of
b b
CLINICAL CHEMISTRY AND
b b b
MOLECULAR DIAGNOSTICS b
7th Edition By Carl A. Burtis
b b b b b
TEST BANK b
,TietzbFundamentalsbofbClinicalbChemistrybandbMolecularbDiagnosticsb7thb EditionbTestbBank
Tablebofbcontents:
I.bPrinciplesbOfbLaboratorybMedicine
Chapterb1.bClinicalbChemistry,bMolecularbDiagnostics,bandbLaboratorybMedicine
Chapterb2.bSelectionbandbAnalyticalbEvaluationbofbMethodsb—bWithbStatisticalbTechniques
Chapterb3.bClinicalbEvaluationbofbMethods
Chapterb4.bEvidence-BasedbLaboratorybMedicine
Chapterb5.bEstablishmentbandbUsebofbReferencebValues
Chapterb6.bSpecimenbCollection,bProcessing,bandbOtherbPreanalyticalbVariables
Chapterb7.bQualitybManagement
II.bAnalyticalbTechniquesbAndbInstrumentation
Chapterb8.bPrinciplesbofbBasicbTechniquesbandbLaboratorybSafety
Chapterb9.bOpticalbTechniques
Chapterb10.bElectrochemistrybandbChemicalbSensors
Chapterb11.bElectrophoresis
Chapterb12.bChromatography
Chapterb13.bMassbSpectrometry
Chapterb14.bEnzymebandbRatebAnalyses
Chapterb15.bImmunochemicalbTechniques
Chapterb16bAutomation
Chapterb17.bPoint-of-CarebInstrumentation
III.b Analytes
Chapterb18.bAminobAcids,bPeptides,bandbProteins
Chapterb19.bSerumbEnzymes
Chapterb20.bTumorbMarkersbandbCancerbGenes
Chapterb21.bKidneybFunctionbTestsb—bCreatinine,bGFR,bUrea,bandbUricbAcid
Chapterb22.bCarbohydrates
Chapterb23.bLipids,bLipoproteins,bApolipoproteins,bandbOtherbCardiacbRiskbFactors
Chapterb24.bElectrolytesbandbBloodbGases
Chapterb25.bHormones
Chapterb26.b CatecholaminesbandbSerotonin
Chapterb27.b Vitamins,bTracebElements,bNutritionalbAssessment
Chapterb28.bHemoglobin,bIron,bandbBilirubin
Chapterb29.bPorphyrinsbandbPorphyrias
Chapterb30.bTherapeuticbDrugsbandbTheirbManagement
Chapterb31.bClinicalbToxicology
Chapterb32.b ToxicbMetals
IV.b Pathophysiology
Chapterb33.bDiabetes
,Chapterb34.b CardiovascularbDisease
Chapterb35.bKidneybDisease
Chapterb36.b PhysiologybandbDisordersbofbWater,bElectrolyte,bandbAcid-BasebMetabolism
Chapterb37.bbLiverbDisease
Chapterb38.b GastrointestinalbandbPancreaticbDiseases
Chapterb39.b DisordersbofbBonebandbMineralbMetabolism
Chapterb40.b DisordersbofbthebPituitarybGland
Chapterb41.b DisordersbofbthebAdrenalbCortex
Chapterb42.b ThyroidbDisorders
Chapterb43.b Reproduction-RelatedbDisorders
Chapterb44.bbPregnancybandbPrenatalbTesting
Chapterb45.b NewbornbScreeningbandb InbornbErrorsbofbMetabolism
Chapterb46.bPharmacogenetics
V.b MolecularbDiagnostics
Chapterb47.bPrinciplesbofbMolecularbBiology
Chapterb48.bNucleicbAcidbTechniquesbandbApplications
Chapterb49.bGenomesbandbNucleicbAcidbAlterations
, TietzbFundamentalsbofbClinicalbChemistrybandbMolecularDiagnostics,b7ebBurtisbTestbBank
Chapterb01:bClinicalbChemistry,bMolecularbDiagnostics,bandbLaboratorybMedicineTestb
Bank
MULTIPLEbCHOICE
1. Anbindividualbworkingbinbabclinicalbchemistryblaboratorybisbmarriedbtobabsalesbrepresentativebw
hobworksbforbabcompanybthatbsellsbchemistryblaboratorybsupplies.bWhenbtheblaboratorybmanage
rbrequestsbablistbofbneededbsupplies,bcostbofbsupplies,bandbvendors,bthisbindividualbonlybrecomme
ndsbthebspouse’sbcompanybasbthebvendor.bThisbisbconsideredbtobbeba(n):
a. accountingbissue.
b. possiblebconflictbofbinterest.
c. maintenancebofbconfidentialitybissue.
d. problembwithbresourceballocation.
ANS:b B
Concernbhasbbeenbraisedboverbthebinterrelationshipsbbetweenbpractitionersbinbthebmedicalbfieldba
ndbcommercialbsuppliersbofbdrugs,bdevices,bequipment,betc.,btobthebmedicalbprofession.
Similarly,brelationshipsbhavebbeenbscrutinizedbbetweenbclinicalblaboratoriansbandbmanufacturer
sbandbprovidersbofbdiagnosticbequipmentbandbsupplies.bThesebconcernsbledbthebNationalbInstitute
sbofbHealthb(NIH)binb1995btobrequirebofficialbinstitutionalbreviewbofbfinancialbdisclosurebbybresea
rchersbandbmanagementbofbsituationsbinbwhichbdisclosurebindicatesbpotentialbconflictsbofbinterest.
DIF: 1 REF:bbbPageb4-5 OBJ:b 6b|b7
2. Abpatientbvisitsbherbphysicianbstatingbthatbherbprescribedbpainkillerbisbnotbworkingbtobreducebt
hebpainbfollowingbherbrecentbsurgery.bAbfriendbofbthebpatientbclaimsbthatbthebsamebpainkillerb“
workedbwonders”btobreducebherbpainbafterbthebsamebsurgery.bThebphysicianbstatesbthatbthebdiff
erencebinbthebeffectbofbthebdrugbmightbbebcausedbby
,bwhichbisbstudiedbinbpharmacogenetics.
a. epidemiology
b. anbinheritedbdisease
c. abconflictbofbinterest
d. abgeneticbvariationbinbdrug-metabolizingbenzymes
ANS:b D
Pharmacogeneticsbisbthebstudybofbthebgeneticbvariationbofbdrugbmetabolismbbetweenbi
ndividuals.
DIF: 1 REF:bbbPageb3 OBJ:b 1
3. Johnbworksbinbabmolecularbdiagnosticsblaboratorybandbreceivesbabbloodbsamplebthatbhasbthebn
amebofbabclosebfriendbprintedbonbthebbar-
codedblabel.bThebgeneticbtestbthatbisborderedbonbthebfriend’sbsamplebwouldbprovidebdiagnosticb
informationbaboutbabdisorderbthatbhasbabpoorbprognosis,bandbthebtestbisbusuallybperformedbbybJ
ohn.bHebasksbabfellowbemployeebtobanalyzebthebsamplebforbhimbandbnotbdivulgebthebresults.bTh
isbethicalbissuebconcerns:
a. confidentialitybofbpatientbgeneticbandbmedicalbinformation.
b. abconflictbofbinterest.
c. resourceballocation.
d. diagnosticbaccuracy.
