TEST BANK PATHOPHYSIOLOG
j j
Y THE BIOLOGIC BASIS FOR DIS
j j j j j
EASEIN ADULTS AND CHILDRE
j j j j
N 8th
j
Edition Kathryn L. McCance, Sue
j j j j
E. Huether
j
, 2
Contents
Chapterj01:jCellularjBiology .............................................................................................................................4
Chapterj02:jAlteredjCellularjandjTissuejBiology:jEnvironmentaljAgents ........................................................ 18
Chapterj03:jThejCellularjEnvironment:jFluidsjandjElectrolytes,jAcidsjandjBases.............................................31
Chapterj04:jGenesjandjGeneticjDiseases....................................................................................................... 44
Chapterj05:jGenes,jEnvironment-Lifestyle,jandjCommonjDiseases ............................................................... 55
Chapterj06:jEpigeneticsjandjDisease ............................................................................................................. 63
Chapterj07:jInnatejImmunity:jInflammationjandjWoundjHealing ................................................................. 68
Chapterj08:jAdaptivejImmunity .................................................................................................................... 83
Chapterj09:jAlterationsjinjImmunityjandjInflammation .................................................................................95
Chapterj10:jInfection .................................................................................................................................. 108
Chapterj11:jStressjandjDisease.....................................................................................................................117
Chapterj12:jCancerjBiology ..........................................................................................................................124
Chapterj13:jCancerjEpidemiology ................................................................................................................ 137
Chapterj14:jCancerjinjChildren .................................................................................................................... 143
Chapterj15:jStructurejandjFunctionjofjthejNeurologicjSystem......................................................................148
Chapterj16:jPain,jTemperaturejRegulation,jSleep,jandjSensoryjFunction..................................................... 159
Chapterj17:jAlterationsjinjCognitivejSystems,jCerebraljHemodynamics,jandjMotorjFunction...................... 174
Chapterj18:jDisordersjofjthejCentraljandjPeripheraljNervousjSystemsjandjthejNeuromuscularjJunction
..................................................................................................................................................................j 188
Chapterj19:jNeurobiologyjofjSchizophrenia,jMoodjDisorders,jandjAnxietyjDisorders .................................. 199
Chapterj20:jAlterationsjofjNeurologicjFunctionjinjChildren .......................................................................... 206
Chapterj21:jMechanismsjofjHormonaljRegulation ....................................................................................... 213
Chapterj22:jAlterationsjofjHormonaljRegulation......................................................................................... 222
Chapterj23:jObesityjandjDisordersjofjNutrition ........................................................................................... 234
Chapterj24:jStructurejandjFunctionjofjthejReproductivejSystems ............................................................... 239
Chapterj25:jAlterationsjofjthejFemalejReproductivejSystem ....................................................................... 249
Chapterj26:jAlterationsjofjthejMalejReproductivejSystem .......................................................................... 259
Chapterj27:jSexuallyjTransmittedjInfections ............................................................................................... 265
Chapterj28:jStructurejandjFunctionjofjthejHematologicjSystem .................................................................. 273
Chapterj29:jAlterationsjofjErythrocytes,jPlatelets,jandjHemostaticjFunction ...............................................283
Chapterj30:jAlterationsjofjLeukocytejandjLymphoidjFunction..................................................................... 293
Chapterj31:jAlterationsjofjHematologicjFunctionjinjChildren .......................................................................300
,Chapterj32:jStructurejandjFunctionjofjthejCardiovascularjandjLymphaticjSystems ...................................... 311
Chapterj33:jAlterationsjofjCardiovascularjFunction .................................................................................... 324
Chapterj34:jAlterationsjofjCardiovascularjFunctionjinjChildren .................................................................... 338
Chapterj35:jStructurejandjFunctionjofjthejPulmonaryjSystem ......................................................................346
Chapterj36:jAlterationsjofjPulmonaryjFunction .......................................................................................... 356
Chapterj37:jAlterationsjofjPulmonaryjFunctionjinjChildren .......................................................................... 373
Chapterj38:jStructurejandjFunctionjofjthejRenaljandjUrologicjSystems ........................................................ 381
Chapterj39:jAlterationsjofjRenaljandjUrinaryjTractjFunction ........................................................................ 391
Chapterj40:jAlterationsjofjRenaljandjUrinaryjTractjFunctionjinjChildren ...................................................... 401
Chapterj41:jStructurejandjFunctionjofjthejDigestivejSystem ........................................................................ 409
Chapterj42:jAlterationsjofjDigestivejFunction ............................................................................................. 421
Chapterj43:jAlterationsjofjDigestivejFunctionjinjChildren............................................................................ 432
Chapterj44:jStructurejandjFunctionjofjthejMusculoskeletaljSystem ............................................................ 441
Chapterj45:jAlterationsjofjMusculoskeletaljFunction.................................................................................. 453
Chapterj46:jAlterationsjofjMusculoskeletaljFunctionjinjChildren ................................................................ 466
Chapterj47:jStructure,jFunction,jandjDisordersjofjthejIntegument .............................................................. 475
Chapterj48:jAlterationsjofjthejIntegumentjinjChildren ................................................................................ 486
Chapterj49:jShock,jMultiplejOrganjDysfunctionjSyndrome,jandjBurnsjinjAdults...........................................494
Chapterj50:jShock,jMultiplejOrganjDysfunctionjSyndrome,jandjBurnsjinjChildren ....................................... 502
, Chapter 01: Cellular Biology
j j j
MULTIPLEjCHOICE
1. Whichjstatementjbestjdescribesjthejcellularjfunctionjofjmetabolicjabsorption?
a. Cellsjcanjproducejproteins.
b. Cellsjcanjsecretejdigestivejenzymes.
c. Cellsjcanjtakejinjandjusejnutrients.
d. Cellsjcanjsynthesizejfats.
ANS:jC
Injmetabolicjabsorption,jalljcellsjtakejinjandjusejnutrientsjandjotherjsubstancesjfromjtheirjsurroundi
ngs.jThejremainingjoptionsjarejnotjinclusivejinjtheirjdescriptionsjofjcellularjmetabolicjabsorption.
PTS:jjj1 DIF: CognitivejLevel:jRemembering
2. Wherejisjmostjofjajcell’sjgeneticjinformation,jincludingjRNAjandjDNA,jcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:jC
Thejnucleusjcontainsjthejnucleolus,jajsmalljdensejstructurejcomposedjlargelyjofjRNA,jmostjofjthejc
ellularjDNA,jandjthejDNA-
bindingjproteins,jsuchjasjthejhistones,jwhichjregulatejitsjactivity.jThejmitochondriajarejresponsiblej
forjcellularjrespirationjandjenergyjproduction.
Ribosomes’jchiefjfunctionjisjtojprovidejsitesjforjcellularjproteinjsynthesis.jLysosomesjfunctionjasjth
ejintracellularjdigestivejsystem.
PTS:jjj1 DIF: CognitivejLevel:jRemembering
3. Whichjcomponentjofjthejcelljproducesjhydrogenjperoxidej(H2O2)jbyjusingjoxygenjtojremovejhyd
rogenjatomsjfromjspecificjsubstratesjinjanjoxidativejreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:jB
j j
Y THE BIOLOGIC BASIS FOR DIS
j j j j j
EASEIN ADULTS AND CHILDRE
j j j j
N 8th
j
Edition Kathryn L. McCance, Sue
j j j j
E. Huether
j
, 2
Contents
Chapterj01:jCellularjBiology .............................................................................................................................4
Chapterj02:jAlteredjCellularjandjTissuejBiology:jEnvironmentaljAgents ........................................................ 18
Chapterj03:jThejCellularjEnvironment:jFluidsjandjElectrolytes,jAcidsjandjBases.............................................31
Chapterj04:jGenesjandjGeneticjDiseases....................................................................................................... 44
Chapterj05:jGenes,jEnvironment-Lifestyle,jandjCommonjDiseases ............................................................... 55
Chapterj06:jEpigeneticsjandjDisease ............................................................................................................. 63
Chapterj07:jInnatejImmunity:jInflammationjandjWoundjHealing ................................................................. 68
Chapterj08:jAdaptivejImmunity .................................................................................................................... 83
Chapterj09:jAlterationsjinjImmunityjandjInflammation .................................................................................95
Chapterj10:jInfection .................................................................................................................................. 108
Chapterj11:jStressjandjDisease.....................................................................................................................117
Chapterj12:jCancerjBiology ..........................................................................................................................124
Chapterj13:jCancerjEpidemiology ................................................................................................................ 137
Chapterj14:jCancerjinjChildren .................................................................................................................... 143
Chapterj15:jStructurejandjFunctionjofjthejNeurologicjSystem......................................................................148
Chapterj16:jPain,jTemperaturejRegulation,jSleep,jandjSensoryjFunction..................................................... 159
Chapterj17:jAlterationsjinjCognitivejSystems,jCerebraljHemodynamics,jandjMotorjFunction...................... 174
Chapterj18:jDisordersjofjthejCentraljandjPeripheraljNervousjSystemsjandjthejNeuromuscularjJunction
..................................................................................................................................................................j 188
Chapterj19:jNeurobiologyjofjSchizophrenia,jMoodjDisorders,jandjAnxietyjDisorders .................................. 199
Chapterj20:jAlterationsjofjNeurologicjFunctionjinjChildren .......................................................................... 206
Chapterj21:jMechanismsjofjHormonaljRegulation ....................................................................................... 213
Chapterj22:jAlterationsjofjHormonaljRegulation......................................................................................... 222
Chapterj23:jObesityjandjDisordersjofjNutrition ........................................................................................... 234
Chapterj24:jStructurejandjFunctionjofjthejReproductivejSystems ............................................................... 239
Chapterj25:jAlterationsjofjthejFemalejReproductivejSystem ....................................................................... 249
Chapterj26:jAlterationsjofjthejMalejReproductivejSystem .......................................................................... 259
Chapterj27:jSexuallyjTransmittedjInfections ............................................................................................... 265
Chapterj28:jStructurejandjFunctionjofjthejHematologicjSystem .................................................................. 273
Chapterj29:jAlterationsjofjErythrocytes,jPlatelets,jandjHemostaticjFunction ...............................................283
Chapterj30:jAlterationsjofjLeukocytejandjLymphoidjFunction..................................................................... 293
Chapterj31:jAlterationsjofjHematologicjFunctionjinjChildren .......................................................................300
,Chapterj32:jStructurejandjFunctionjofjthejCardiovascularjandjLymphaticjSystems ...................................... 311
Chapterj33:jAlterationsjofjCardiovascularjFunction .................................................................................... 324
Chapterj34:jAlterationsjofjCardiovascularjFunctionjinjChildren .................................................................... 338
Chapterj35:jStructurejandjFunctionjofjthejPulmonaryjSystem ......................................................................346
Chapterj36:jAlterationsjofjPulmonaryjFunction .......................................................................................... 356
Chapterj37:jAlterationsjofjPulmonaryjFunctionjinjChildren .......................................................................... 373
Chapterj38:jStructurejandjFunctionjofjthejRenaljandjUrologicjSystems ........................................................ 381
Chapterj39:jAlterationsjofjRenaljandjUrinaryjTractjFunction ........................................................................ 391
Chapterj40:jAlterationsjofjRenaljandjUrinaryjTractjFunctionjinjChildren ...................................................... 401
Chapterj41:jStructurejandjFunctionjofjthejDigestivejSystem ........................................................................ 409
Chapterj42:jAlterationsjofjDigestivejFunction ............................................................................................. 421
Chapterj43:jAlterationsjofjDigestivejFunctionjinjChildren............................................................................ 432
Chapterj44:jStructurejandjFunctionjofjthejMusculoskeletaljSystem ............................................................ 441
Chapterj45:jAlterationsjofjMusculoskeletaljFunction.................................................................................. 453
Chapterj46:jAlterationsjofjMusculoskeletaljFunctionjinjChildren ................................................................ 466
Chapterj47:jStructure,jFunction,jandjDisordersjofjthejIntegument .............................................................. 475
Chapterj48:jAlterationsjofjthejIntegumentjinjChildren ................................................................................ 486
Chapterj49:jShock,jMultiplejOrganjDysfunctionjSyndrome,jandjBurnsjinjAdults...........................................494
Chapterj50:jShock,jMultiplejOrganjDysfunctionjSyndrome,jandjBurnsjinjChildren ....................................... 502
, Chapter 01: Cellular Biology
j j j
MULTIPLEjCHOICE
1. Whichjstatementjbestjdescribesjthejcellularjfunctionjofjmetabolicjabsorption?
a. Cellsjcanjproducejproteins.
b. Cellsjcanjsecretejdigestivejenzymes.
c. Cellsjcanjtakejinjandjusejnutrients.
d. Cellsjcanjsynthesizejfats.
ANS:jC
Injmetabolicjabsorption,jalljcellsjtakejinjandjusejnutrientsjandjotherjsubstancesjfromjtheirjsurroundi
ngs.jThejremainingjoptionsjarejnotjinclusivejinjtheirjdescriptionsjofjcellularjmetabolicjabsorption.
PTS:jjj1 DIF: CognitivejLevel:jRemembering
2. Wherejisjmostjofjajcell’sjgeneticjinformation,jincludingjRNAjandjDNA,jcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:jC
Thejnucleusjcontainsjthejnucleolus,jajsmalljdensejstructurejcomposedjlargelyjofjRNA,jmostjofjthejc
ellularjDNA,jandjthejDNA-
bindingjproteins,jsuchjasjthejhistones,jwhichjregulatejitsjactivity.jThejmitochondriajarejresponsiblej
forjcellularjrespirationjandjenergyjproduction.
Ribosomes’jchiefjfunctionjisjtojprovidejsitesjforjcellularjproteinjsynthesis.jLysosomesjfunctionjasjth
ejintracellularjdigestivejsystem.
PTS:jjj1 DIF: CognitivejLevel:jRemembering
3. Whichjcomponentjofjthejcelljproducesjhydrogenjperoxidej(H2O2)jbyjusingjoxygenjtojremovejhyd
rogenjatomsjfromjspecificjsubstratesjinjanjoxidativejreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:jB
