PRE-TEST PHYSIOLOGY CYCLE 4
Chronic administration of which of the following types of drugs
would lead to a sustained increase in serum gastrin levels?
a. H2 receptor antagonist
b. Proton pump inhibitor
c. Anticholinergic
d. Antacid
e. Beta blocker
B. Proton pump inhibitor
Which one of the following statements about small intestinal motility is correct?
a. Contractile frequency is constant from duodenum to terminal ileum
b. Peristalsis is the major contractile pattern during feeding
c. Migrating motor complexes occur during the digestive period
d. Vagotomy abolishes contractile activity during the digestive period
e. Contractile activity is initiated in response to bowel wall distention
E. Contractile activity is initiated in response to bowel wall distention
Which one of the following statements about gastric emptying is correct?
a. Solids empty more rapidly than liquids
b. Vagotomy accelerates the emptying of solids
c. Indigestible food empties during the digestive period
d. Acidification of the antrum decreases gastric emptying
e. Vagotomy decreases accommodation of the proximal stomach
E. Vagotomy decreases accommodation of the proximal stomach
Vitamin B12 is absorbed primarily in the:
a. Stomach
b. Duodenum
c. Jejunum
d. Ileum
e. Colon
D. Ileum (distal)
The principal paracrine secretion involved in the inhibitory feedback
regulation of gastric acid secretion is:
a. Gastrin
b. Somatostatin
c. Histamine
d. Enterogastrone
e. Acetylcholine
B. Stomatostatin
, Which one of the following is the putative inhibitory neurotransmitter
responsible for relaxation of gastrointestinal smooth muscle?
a. Dopamine
b. Vasoactive intestinal peptide
c. Somatostatin
d. Substance P
e. Acetylcholine
B. Vasoactive intestinal peptide
Cholera toxin causes diarrhea by inhibiting:
a. Neutral NaCl absorption in the small intestine
b. Electrogenic Na absorption from the small intestine
c. Na-glucose coupled absorption from the small intestine
d. Na/H exchange in the small intestine
e. Electrogenic Na absorption from the colon
A. Neutral NaCl absorption in the small intestine
Which one of the following statements best describes water and electrolyte
absorption in the GI tract?
a. Most water and electrolytes come from ingested fluids
b. The small intestine and colon have similar absorptive capacities
c. Osmotic equilibration of chyme occurs in the stomach
d. The majority of absorption occurs in the jejunum
e. Water absorption is independent of Na+ absorption
D. The majority of absorption occurs in the jejunum
Hypokalemic metabolic acidosis can occur with excess fluid loss
from the:
a. Stomach
b. Ileum
c. Colon
d. Pancreas
e. Liver
C. Colon
Which gastrointestinal motor activity is most affected by vagotomy?
a. Secondary esophageal peristalsis
b. Distention-induced intestinal segmentation
c. Orad stomach accommodation
d. Caudad stomach peristalsis
e. Migrating motor complexes
C. Orad stomach accommodation
The hormone involved in the initiation of the migrating motor complex is:
a. Gastrin
Chronic administration of which of the following types of drugs
would lead to a sustained increase in serum gastrin levels?
a. H2 receptor antagonist
b. Proton pump inhibitor
c. Anticholinergic
d. Antacid
e. Beta blocker
B. Proton pump inhibitor
Which one of the following statements about small intestinal motility is correct?
a. Contractile frequency is constant from duodenum to terminal ileum
b. Peristalsis is the major contractile pattern during feeding
c. Migrating motor complexes occur during the digestive period
d. Vagotomy abolishes contractile activity during the digestive period
e. Contractile activity is initiated in response to bowel wall distention
E. Contractile activity is initiated in response to bowel wall distention
Which one of the following statements about gastric emptying is correct?
a. Solids empty more rapidly than liquids
b. Vagotomy accelerates the emptying of solids
c. Indigestible food empties during the digestive period
d. Acidification of the antrum decreases gastric emptying
e. Vagotomy decreases accommodation of the proximal stomach
E. Vagotomy decreases accommodation of the proximal stomach
Vitamin B12 is absorbed primarily in the:
a. Stomach
b. Duodenum
c. Jejunum
d. Ileum
e. Colon
D. Ileum (distal)
The principal paracrine secretion involved in the inhibitory feedback
regulation of gastric acid secretion is:
a. Gastrin
b. Somatostatin
c. Histamine
d. Enterogastrone
e. Acetylcholine
B. Stomatostatin
, Which one of the following is the putative inhibitory neurotransmitter
responsible for relaxation of gastrointestinal smooth muscle?
a. Dopamine
b. Vasoactive intestinal peptide
c. Somatostatin
d. Substance P
e. Acetylcholine
B. Vasoactive intestinal peptide
Cholera toxin causes diarrhea by inhibiting:
a. Neutral NaCl absorption in the small intestine
b. Electrogenic Na absorption from the small intestine
c. Na-glucose coupled absorption from the small intestine
d. Na/H exchange in the small intestine
e. Electrogenic Na absorption from the colon
A. Neutral NaCl absorption in the small intestine
Which one of the following statements best describes water and electrolyte
absorption in the GI tract?
a. Most water and electrolytes come from ingested fluids
b. The small intestine and colon have similar absorptive capacities
c. Osmotic equilibration of chyme occurs in the stomach
d. The majority of absorption occurs in the jejunum
e. Water absorption is independent of Na+ absorption
D. The majority of absorption occurs in the jejunum
Hypokalemic metabolic acidosis can occur with excess fluid loss
from the:
a. Stomach
b. Ileum
c. Colon
d. Pancreas
e. Liver
C. Colon
Which gastrointestinal motor activity is most affected by vagotomy?
a. Secondary esophageal peristalsis
b. Distention-induced intestinal segmentation
c. Orad stomach accommodation
d. Caudad stomach peristalsis
e. Migrating motor complexes
C. Orad stomach accommodation
The hormone involved in the initiation of the migrating motor complex is:
a. Gastrin
