Sue E. Huether, Kathryn L. McCance -
r r r r r r
Test Bank for Understanding Pathophysiology (6t
r r r r r r
h Ed)-Test Bank (complete questions & answers)
r r r r r r
Chapter 01: Cellular Biology
r r r
Huether & McCance: Understanding Pathophysiology, 6th Edition
r r r r r r
MULTIPLErCHOICE
1. Arstudentrisrobservingrarcellrunderrthermicroscope.rItrisrobservedrtorhaversupercoiledrDNArwit
hrhistones.rWhichrofrtherfollowingrwouldralsorberobservedrbyrtherstudent?
a. Arsinglercircularrchromosome
b. Arnucleus
c. Free-floatingrnuclearrmaterial
d. Nororganelles
ANS:r B
Thercellrdescribedrisrareukaryoticrcell,rsoritrhasrhistonesrandrarsupercoiledrDNArwithinritsrnucl
eus;rthus,rthernucleusrshouldrberobserved.rArsinglercircularrchromosomercalledrarprokaryoterc
ontainsrfree-floatingrnuclearrmaterialrbutrhasrnororganelles.
REF:r p.r2
2. Arnurserisrinstructingrtherstaffraboutrcellularrfunctions.rWhichrcellularrfunctionrisrthernurserdesc
ribingrwhenranrisolatedrcellrabsorbsroxygenrandrusesritrtortransformrnutrientsrtorenergy?
a. Metabolicrabsorption
b. Communication
c. Secretion
d. Respiration
ANS:r D NURSINGTB.COM
Thercell’srabilityrtorabsorbroxygenrisrreferredrtorasrrespirationrwhileritsrcommunicationrabilityrinv
olvesrmaintenancerofrarsteadyrdynamicrstate,rmetabolicrabsorptionrprovidesrnutrition,randrsecreti
onrallowsrforrthersynthesizingrofrnewrsubstances.
REF:r p.r2
3. AreukaryoticrcellrisrundergoingrDNArreplication.rInrwhichrregionrofrthercellrwouldrmostrofrther
geneticrinformationrbercontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusrCytoplasm
ANS:r C
Therregionrofrthercellrthatrcontainsrgeneticrmaterial,rincludingrarlargeramountrofrribonucleicraci
d,rmostrofrtherDNA,randrDNA-
bindingrproteins,risrthernucleolus,rwhichrisrlocatedrwithinrthercell’srnucleus.rMitochondriarisrass
ociatedrwithrcellularrrespiration,rwhilerribosomesrarerinvolvedrwithrproteinrmanufacturing.rCyt
oplasmrisrarfluidrfillingrthatrisrarcomponentrofrthercell.
REF:r p.r2
NURSINGTB.COM
,Sue E. Huether, Kathryn L. McCance -
r r r r r r
Test Bank for Understanding Pathophysiology (6t
r r r r r r
h Ed)-Test Bank (complete questions & answers)
r r r r r r
4. Whichrofrtherfollowingrcanrremoverproteinsrattachedrtorthercell’srbilayerrbyrdissolvingrtherlay
erritself?
a. Peripheralrmembranerproteins
b. Integralrmembranerproteins
c. Glycoproteins
d. Cellradhesionrmolecules
ANS:r B
Proteinsrdirectlyrattachedrtorthermembranerbilayerrcanrberremovedrbyrtheractionrofrintegralrme
mbranerproteinsrthatrdissolvertherbilayer.rPeripheralrmembranerproteinsrresideratrthersurfacerw
hilercellradhesionrmoleculesrareronrtheroutsiderofrthermembrane.rGlycoproteinrmarksrcellsrandr
doesrnotrfloat.
REF:r p.r7
5. Whichrofrtherfollowingrcanrbindrtorplasmarmembranerreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicrlipids
d. Ligands
ANS:r D
Ligandsrarertheronlyrspecificrmoleculesrthatrcanrbindrwithrreceptorsronrthercellrmembrane.
REF:r p.r9
6. Arnurserisrreviewingrarreportrfromrarpatientrwithrmetastaticrcancer.rWhatralternationrinrtherextr
acellularrmatrixrwouldrsuN
ppoR
rtrthIerdGagnBo.
siC
srofM
a. Decreasedrfibronectin
UrSirN rT
metastaticrcancer?
O
b. Increasedrcollagen
c. Decreasedrelastin
d. Increasedrglycoproteins
ANS:r A
Onlyrarreducedramountrofrfibronectinrisrfoundrinrsomertypesrofrcancerousrcells,rallowingrthe
mrtortravelrorrmetastasize.
REF:r p.r10
7. Whichrformrofrcellrcommunicationrisrusedrtorrelatertorotherrcellsrinrdirectrphysicalrcontact?
a. Cellrjunction
b. Gaprjunction
c. Desmosome
d. Tightrjunction
ANS:r A
Cellrjunctionsrholdrcellsrtogetherrandrpermitrmoleculesrtorpassrfromrcellrtorcell.
Gaprjunctionsrallowrforrcellularrcommunicationrbetweenrcells.rNeitherrdesmosomesrnorrtightrjun
ctionsrarerassociatedrwithrcellularrcommunication.
NURSINGTB.COM
,Sue E. Huether, Kathryn L. McCance -
r r r r r r
Test Bank for Understanding Pathophysiology (6t
r r r r r r
h Ed)-Test Bank (complete questions & answers)
r r r r r r
REF:r p.r11
NURSINGTB.COM
, Sue E. Huether, Kathryn L. McCance -
r r r r r r
Test Bank for Understanding Pathophysiology (6t
r r r r r r
h Ed)-Test Bank (complete questions & answers)
r r r r r r
8. Pancreaticrbetarcellsrsecreterinsulin,rwhichrinhibitsrsecretionrofrglucagonrfromrneighboringralp
harcells.rThisractionrisranrexamplerofrwhichrofrtherfollowingrsignalingrtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:r A
Paracrinersignalingrinvolvesrtherreleaserofrlocalrchemicalrmediatorsrthatrarerquicklyrtakenrup,rdes
troyed,rorrimmobilized,rasrinrthercaserofrinsulinrandrtherinhibitionrofrthersecretionrofrglucagon.rN
onerofrtherotherroptionsrinvolversignalingrthatrisrassociatedrwithrarlocalrchemicalrmediatorrlikerins
ulin.
REF:r p.r12
9. Inrcellularrmetabolism,reachrenzymerhasrarhighraffinityrforra:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:r B
Eachrenzymerhasrarhighraffinityrforrarsubstrate,rarspecificrsubstancerconvertedrtorarproductrofrtherr
eaction.rCellularrmetabolismrisrnotrdependentronranrattractionrbetweenranrenzymerandranyrofrther
remainingroptions.
REF:rrr p.r16
NURSINGTB.COM
10. Anrathleterrunsrarmarathon,rafterrwhichrhisrmusclesrfeelrfatiguedrandrunablertorcontract.rTherathle
terasksrthernurserwhyrthisrhappened.rThernurse’srresponserisrbasedronrtherknowledgerthatrtherprobl
emrisrresultrofrardeficiencyrof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:r C
WhenrATPrisrdeficient,rimpairedrmusclercontractionrresults.rNonerofrtherotherroptionsrarerinv
olvedrinrmusclercontraction.
REF:r p.r16
11. WhichrphaserofrcatabolismrproducesrthermostrATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricracidrcycle
ANS:r D
NURSINGTB.COM
r r r r r r
Test Bank for Understanding Pathophysiology (6t
r r r r r r
h Ed)-Test Bank (complete questions & answers)
r r r r r r
Chapter 01: Cellular Biology
r r r
Huether & McCance: Understanding Pathophysiology, 6th Edition
r r r r r r
MULTIPLErCHOICE
1. Arstudentrisrobservingrarcellrunderrthermicroscope.rItrisrobservedrtorhaversupercoiledrDNArwit
hrhistones.rWhichrofrtherfollowingrwouldralsorberobservedrbyrtherstudent?
a. Arsinglercircularrchromosome
b. Arnucleus
c. Free-floatingrnuclearrmaterial
d. Nororganelles
ANS:r B
Thercellrdescribedrisrareukaryoticrcell,rsoritrhasrhistonesrandrarsupercoiledrDNArwithinritsrnucl
eus;rthus,rthernucleusrshouldrberobserved.rArsinglercircularrchromosomercalledrarprokaryoterc
ontainsrfree-floatingrnuclearrmaterialrbutrhasrnororganelles.
REF:r p.r2
2. Arnurserisrinstructingrtherstaffraboutrcellularrfunctions.rWhichrcellularrfunctionrisrthernurserdesc
ribingrwhenranrisolatedrcellrabsorbsroxygenrandrusesritrtortransformrnutrientsrtorenergy?
a. Metabolicrabsorption
b. Communication
c. Secretion
d. Respiration
ANS:r D NURSINGTB.COM
Thercell’srabilityrtorabsorbroxygenrisrreferredrtorasrrespirationrwhileritsrcommunicationrabilityrinv
olvesrmaintenancerofrarsteadyrdynamicrstate,rmetabolicrabsorptionrprovidesrnutrition,randrsecreti
onrallowsrforrthersynthesizingrofrnewrsubstances.
REF:r p.r2
3. AreukaryoticrcellrisrundergoingrDNArreplication.rInrwhichrregionrofrthercellrwouldrmostrofrther
geneticrinformationrbercontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusrCytoplasm
ANS:r C
Therregionrofrthercellrthatrcontainsrgeneticrmaterial,rincludingrarlargeramountrofrribonucleicraci
d,rmostrofrtherDNA,randrDNA-
bindingrproteins,risrthernucleolus,rwhichrisrlocatedrwithinrthercell’srnucleus.rMitochondriarisrass
ociatedrwithrcellularrrespiration,rwhilerribosomesrarerinvolvedrwithrproteinrmanufacturing.rCyt
oplasmrisrarfluidrfillingrthatrisrarcomponentrofrthercell.
REF:r p.r2
NURSINGTB.COM
,Sue E. Huether, Kathryn L. McCance -
r r r r r r
Test Bank for Understanding Pathophysiology (6t
r r r r r r
h Ed)-Test Bank (complete questions & answers)
r r r r r r
4. Whichrofrtherfollowingrcanrremoverproteinsrattachedrtorthercell’srbilayerrbyrdissolvingrtherlay
erritself?
a. Peripheralrmembranerproteins
b. Integralrmembranerproteins
c. Glycoproteins
d. Cellradhesionrmolecules
ANS:r B
Proteinsrdirectlyrattachedrtorthermembranerbilayerrcanrberremovedrbyrtheractionrofrintegralrme
mbranerproteinsrthatrdissolvertherbilayer.rPeripheralrmembranerproteinsrresideratrthersurfacerw
hilercellradhesionrmoleculesrareronrtheroutsiderofrthermembrane.rGlycoproteinrmarksrcellsrandr
doesrnotrfloat.
REF:r p.r7
5. Whichrofrtherfollowingrcanrbindrtorplasmarmembranerreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicrlipids
d. Ligands
ANS:r D
Ligandsrarertheronlyrspecificrmoleculesrthatrcanrbindrwithrreceptorsronrthercellrmembrane.
REF:r p.r9
6. Arnurserisrreviewingrarreportrfromrarpatientrwithrmetastaticrcancer.rWhatralternationrinrtherextr
acellularrmatrixrwouldrsuN
ppoR
rtrthIerdGagnBo.
siC
srofM
a. Decreasedrfibronectin
UrSirN rT
metastaticrcancer?
O
b. Increasedrcollagen
c. Decreasedrelastin
d. Increasedrglycoproteins
ANS:r A
Onlyrarreducedramountrofrfibronectinrisrfoundrinrsomertypesrofrcancerousrcells,rallowingrthe
mrtortravelrorrmetastasize.
REF:r p.r10
7. Whichrformrofrcellrcommunicationrisrusedrtorrelatertorotherrcellsrinrdirectrphysicalrcontact?
a. Cellrjunction
b. Gaprjunction
c. Desmosome
d. Tightrjunction
ANS:r A
Cellrjunctionsrholdrcellsrtogetherrandrpermitrmoleculesrtorpassrfromrcellrtorcell.
Gaprjunctionsrallowrforrcellularrcommunicationrbetweenrcells.rNeitherrdesmosomesrnorrtightrjun
ctionsrarerassociatedrwithrcellularrcommunication.
NURSINGTB.COM
,Sue E. Huether, Kathryn L. McCance -
r r r r r r
Test Bank for Understanding Pathophysiology (6t
r r r r r r
h Ed)-Test Bank (complete questions & answers)
r r r r r r
REF:r p.r11
NURSINGTB.COM
, Sue E. Huether, Kathryn L. McCance -
r r r r r r
Test Bank for Understanding Pathophysiology (6t
r r r r r r
h Ed)-Test Bank (complete questions & answers)
r r r r r r
8. Pancreaticrbetarcellsrsecreterinsulin,rwhichrinhibitsrsecretionrofrglucagonrfromrneighboringralp
harcells.rThisractionrisranrexamplerofrwhichrofrtherfollowingrsignalingrtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:r A
Paracrinersignalingrinvolvesrtherreleaserofrlocalrchemicalrmediatorsrthatrarerquicklyrtakenrup,rdes
troyed,rorrimmobilized,rasrinrthercaserofrinsulinrandrtherinhibitionrofrthersecretionrofrglucagon.rN
onerofrtherotherroptionsrinvolversignalingrthatrisrassociatedrwithrarlocalrchemicalrmediatorrlikerins
ulin.
REF:r p.r12
9. Inrcellularrmetabolism,reachrenzymerhasrarhighraffinityrforra:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:r B
Eachrenzymerhasrarhighraffinityrforrarsubstrate,rarspecificrsubstancerconvertedrtorarproductrofrtherr
eaction.rCellularrmetabolismrisrnotrdependentronranrattractionrbetweenranrenzymerandranyrofrther
remainingroptions.
REF:rrr p.r16
NURSINGTB.COM
10. Anrathleterrunsrarmarathon,rafterrwhichrhisrmusclesrfeelrfatiguedrandrunablertorcontract.rTherathle
terasksrthernurserwhyrthisrhappened.rThernurse’srresponserisrbasedronrtherknowledgerthatrtherprobl
emrisrresultrofrardeficiencyrof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:r C
WhenrATPrisrdeficient,rimpairedrmusclercontractionrresults.rNonerofrtherotherroptionsrarerinv
olvedrinrmusclercontraction.
REF:r p.r16
11. WhichrphaserofrcatabolismrproducesrthermostrATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricracidrcycle
ANS:r D
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