VITAMINS
VITAMIN D
BIOLOGICAL FUNCTION
Action of calcitriol on the intestine: Calcitriol increase the intestinal absorption of calcium
and phosphate.
In the intestinal cells, calcitriol binds with a cytosolic receptor to form a calcitriol-receptor
complex.
This complex then approaches the nucleus and interacts with a specific DNA leading to
synthesis of a specific calcium binding protein.
This protein increases the calcium uptake by the intestine.
DEFICIENCY
Rickets
Sleep changes
Fatigue
Weakness of Muscle strength
Back pain
VITAMIN E
BIOLOGICAL FUNCTIONS
Antioxidant role: Vitamin-E is the most potent natural antioxidant.
Removal of Free radicals: Vitamin-E removes free radicals, prevents their peroxidative effects
on unsaturated lipids of membrane and thus maintains integrity of membranes.
Role in Heme Synthesis: Vitamin-E also takes part in the synthesis of heme. Vitamin-E induces
enzymes ALA-synthase and ALA-dehydratase.
DEFICIENCY
VITAMIN D
BIOLOGICAL FUNCTION
Action of calcitriol on the intestine: Calcitriol increase the intestinal absorption of calcium
and phosphate.
In the intestinal cells, calcitriol binds with a cytosolic receptor to form a calcitriol-receptor
complex.
This complex then approaches the nucleus and interacts with a specific DNA leading to
synthesis of a specific calcium binding protein.
This protein increases the calcium uptake by the intestine.
DEFICIENCY
Rickets
Sleep changes
Fatigue
Weakness of Muscle strength
Back pain
VITAMIN E
BIOLOGICAL FUNCTIONS
Antioxidant role: Vitamin-E is the most potent natural antioxidant.
Removal of Free radicals: Vitamin-E removes free radicals, prevents their peroxidative effects
on unsaturated lipids of membrane and thus maintains integrity of membranes.
Role in Heme Synthesis: Vitamin-E also takes part in the synthesis of heme. Vitamin-E induces
enzymes ALA-synthase and ALA-dehydratase.
DEFICIENCY
