Test bank for pharmacotherapeutics for advanced practice a practical approach 5th editio

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Pharmacotherapeutics for advanced practice a practicala
x x x x x x




pproach 5th edition test bank
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Pharmacology for Nurses (Mercy College)
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Chapter 1 Issues for the Practitioner in Drug Therapy
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MULTIPLExCHOICE

1. Nursexpractitionerxprescriptivexauthorityxisxregulatedxby:
A. ThexNationalxCouncilxofxStatexBoardsxofxNursing
B. ThexU.S.xDrugxEnforcementxAdministration
C. ThexStatexBoardxofxNursingxforxeachxstate
D. ThexStatexBoardxofxPharmacy
ANS:x C PTS:x 1

2. PhysicianxAssistantx(PA)xprescriptivexauthorityxisxregulatedxby:
A. ThexNationalxCouncilxofxStatexBoardsxofxNursing
B. ThexU.S.xDrugxEnforcementxAdministration
C. ThexStatexBoardxofxNursing
D. ThexStatexBoardxofxMedicalxExaminers
ANS:x D PTS:x 1

3. Clinicalxjudgmentxinxprescribingxincludes:
A. Factoringxinxthexcostxtoxthexpatientxofxthexmedicationxprescribed
B. Alwaysxprescribingxthexnewestxmedicationxavailablexforxthexdiseasexprocess
C. Handingxoutxdrugxsamplesxtoxpoorxpatients
D. Prescribingxallxgenericxmedicationsxtoxcutxcosts
ANS:x A PTS:x 1

4. Criteriaxforxchoosingxanxeffectivexdrugxforxaxdisorderxinclude:
A. Askingxthexpatientxwhatxdrugxtheyxthinkxwouldxworkxbestxforxthem
B. Consultingxnationallyxrecognizedxguidelinesxforxdiseasexmanagement
C. Prescribingxmedicationsxthatxarexavailablexasxsamplesxbeforexwritingxaxprescription
D. FollowingxU.S.xDrugxEnforcementxAdministrationx(DEA)xguidelinesxforx
prescribing
ANS:x B PTS:x 1

5. Nursexpractitionerxpracticexmayxthrivexunderxhealth-carexreformxduexto:
A. Thexdemonstratedxabilityxofxnursexpractitionersxtoxcontrolxcostsxandximprovexpatientx
outcomes
B. Thexfactxthatxnursexpractitionersxwillxbexablextoxpracticexindependently
C. Thexfactxthatxnursexpractitionersxwillxhavexfullxreimbursementxunderxhealth-
carexreform
D. ThexabilityxtoxshiftxaccountabilityxforxMedicaidxtoxthexstatexlevel
ANS:x A PTS:x 1

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Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
x x x x x x




MULTIPLExCHOICE

1. Axpatient’sxnutritionalxintakexandxlabxworkxreflectsxhypoalbuminemia.xThisxisxcriticalxtoxp
rescribingxbecause:
A. Distributionxofxdrugsxtoxtargetxtissuexmayxbexaffected
B. Thexsolubilityxofxthexdrugxwillxnotxmatchxthexsitexofxabsorption
C. Therexwillxbexlessxfreexdrugxavailablextoxgeneratexanxeffect
D. Drugsxboundxtoxalbuminxarexreadilyxexcretedxbyxthexkidney
ANS:x A PTS:x 1

2. Drugsxthatxhavexaxsignificantxfirst-passxeffect:
A. Mustxbexgivenxbyxthexenteralx(oral)xroutexonly
B. Bypassxthexhepaticxcirculation
C. Arexrapidlyxmetabolizedxbyxthexliverxandxmayxhavexlittlexifxanyxdesiredxaction
D. Arexconvertedxbyxthexliverxtoxmorexactivexandxfat-solublexforms
ANS:x C PTS:x 1

3. Thexroutexofxexcretionxofxaxvolatilexdrugxwillxlikelyxbe:
A. Thexkidneys
B. Thexlungs
C. Thexbilexandxfeces
D. Thexskin
ANS:x B PTS:x 1

4. Medroxyprogesteronex(DepoxProvera)xisxprescribedxIMxtoxcreatexaxstoragexreservoirxofxthexd
rug.xStoragexreservoirs:
A. Assurexthatxthexdrugxwillxreachxitsxintendedxtargetxtissue
B. Arexthexreasonxforxgivingxloadingxdoses
C. Increasexthexlengthxofxtimexaxdrugxisxavailablexandxactive
D. Arexmostxcommonxinxcollagenxtissues
ANS:x C PTS:x 1

5. ThexNPxchoosesxtoxgivexcephalexinxeveryx8xhoursxbasedxonxknowledgexofxthexdrug’s:
A. Propensityxtoxgoxtoxthextargetxreceptor
B. Biologicalxhalf-life
C. Pharmacodynamics
D. Safetyxandxsidexeffects
ANS:x B PTS:x 1

6. Azithromycinxdosingxrequiresxthexfirstxday’sxdosexbextwicexthosexofxthexotherx4xdaysxofxthexp
rescription.xThisxisxconsideredxaxloadingxdose.xAxloadingxdose:
A. Rapidlyxachievesxdrugxlevelsxinxthextherapeuticxrange
B. Requiresxfourxtoxfivexhalf-livesxtoxattain
C. Isxinfluencedxbyxrenalxfunction

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D. Isxdirectlyxrelatedxtoxthexdrugxcirculatingxtoxthextargetxtissues
ANS:x A PTS:x 1

7. Thexpointxinxtimexonxthexdrugxconcentrationxcurvexthatxindicatesxthexfirstxsignxofxaxtherapeuticxe
ffectxisxthe:
A. Minimumxadversexeffectxlevel
B. Peakxofxaction
C. Onsetxofxaction
D. Therapeuticxrange
ANS:x C PTS:x 1

8. Phenytoinxrequiresxaxtroughxlevelxbexdrawn.xPeakxandxtroughxlevelsxarexdone:
A. Whenxthexdrugxhasxaxwidextherapeuticxrange
B. Whenxthexdrugxwillxbexadministeredxforxaxshortxtimexonly
C. Whenxtherexisxaxhighxcorrelationxbetweenxthexdosexandxsaturationxofxreceptorxsites
D. Toxdeterminexifxaxdrugxisxinxthextherapeuticxrange
ANS:x D PTS:x 1

9. Axlaboratoryxresultxindicatesxthexpeakxlevelxforxaxdrugxisxabovexthexminimumxtoxicxc
oncentration.xThisxmeansxthatxthe:
A. Concentrationxwillxproducextherapeuticxeffects
B. Concentrationxwillxproducexanxadversexresponse
C. Timexbetweenxdosesxmustxbexshortened
D. Durationxofxactionxofxthexdrugxisxtooxlong
ANS:x B PTS:x 1

10. Drugsxthatxarexreceptorxagonistsxmayxdemonstratexwhatxproperty?
A. Irreversiblexbindingxtoxthexdrugxreceptorxsite
B. Up-regulationxwithxchronicxuse
C. Desensitizationxorxdown-regulationxwithxcontinuousxuse
D. Inversexrelationshipxbetweenxdrugxconcentrationxandxdrugxaction
ANS:x C PTS:x 1

11. Drugsxthatxarexreceptorxantagonists,xsuchxasxbetaxblockers,xmayxcause:
A. Down-regulationxofxthexdrugxreceptor
B. Anxexaggeratedxresponsexifxabruptlyxdiscontinued
C. Partialxblockadexofxthexeffectsxofxagonistxdrugs
D. Anxexaggeratedxresponsextoxcompetitivexdrugxagonists
ANS:x B PTS:x 1

12. Factorsxthatxaffectxgastricxdrugxabsorptionxinclude:
A. Liverxenzymexactivity
B. Protein-bindingxpropertiesxofxthexdrugxmolecule
C. Lipidxsolubilityxofxthexdrug
D. Abilityxtoxchewxandxswallow
ANS:x C PTS:x 1