Test bank for pharmacotherapeutics for advanced practice a practical approach 5th edition

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Pharmacotherapeutics for advanced practice a practicala
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pproach 5th edition test bank
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Pharmacology for Nurses (Mercy College)
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Chapter 1 Issues for the Practitioner in Drug Therapy
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MULTIPLEzCHOICE

1. Nursezpractitionerzprescriptivezauthorityziszregulatedzby:
A. ThezNationalzCouncilzofzStatezBoardszofzNursing
B. ThezU.S.zDrugzEnforcementzAdministration
C. ThezStatezBoardzofzNursingzforzeachzstate
D. ThezStatezBoardzofzPharmacy
ANS:z C PTS:z 1

2. PhysicianzAssistantz(PA)zprescriptivezauthorityziszregulatedzby:
A. ThezNationalzCouncilzofzStatezBoardszofzNursing
B. ThezU.S.zDrugzEnforcementzAdministration
C. ThezStatezBoardzofzNursing
D. ThezStatezBoardzofzMedicalzExaminers
ANS:z D PTS:z 1

3. Clinicalzjudgmentzinzprescribingzincludes:
A. Factoringzinzthezcostztozthezpatientzofzthezmedicationzprescribed
B. Alwayszprescribingztheznewestzmedicationzavailablezforzthezdiseasezprocess
C. Handingzoutzdrugzsamplesztozpoorzpatients
D. Prescribingzallzgenericzmedicationsztozcutzcosts
ANS:z A PTS:z 1

4. Criteriazforzchoosingzanzeffectivezdrugzforzazdisorderzinclude:
A. Askingzthezpatientzwhatzdrugztheyzthinkzwouldzworkzbestzforzthem
B. Consultingznationallyzrecognizedzguidelineszforzdiseasezmanagement
C. Prescribingzmedicationszthatzarezavailablezaszsampleszbeforezwritingzazprescription
D. FollowingzU.S.zDrugzEnforcementzAdministrationz(DEA)zguidelineszforz
prescribing
ANS:z B PTS:z 1

5. Nursezpractitionerzpracticezmayzthrivezunderzhealth-carezreformzduezto:
A. Thezdemonstratedzabilityzofznursezpractitionersztozcontrolzcostszandzimprovezpatientzo
utcomes
B. Thezfactzthatznursezpractitionerszwillzbezableztozpracticezindependently
C. Thezfactzthatznursezpractitionerszwillzhavezfullzreimbursementzunderzhealth-
carezreform
D. ThezabilityztozshiftzaccountabilityzforzMedicaidztozthezstatezlevel
ANS:z A PTS:z 1

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Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
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MULTIPLEzCHOICE

1. Azpatient’sznutritionalzintakezandzlabzworkzreflectszhypoalbuminemia.zThisziszcriticalztozp
rescribingzbecause:
A. Distributionzofzdrugsztoztargetztissuezmayzbezaffected
B. Thezsolubilityzofzthezdrugzwillznotzmatchzthezsitezofzabsorption
C. Therezwillzbezlesszfreezdrugzavailableztozgeneratezanzeffect
D. Drugszboundztozalbuminzarezreadilyzexcretedzbyzthezkidney
ANS:z A PTS:z 1

2. Drugszthatzhavezazsignificantzfirst-passzeffect:
A. Mustzbezgivenzbyzthezenteralz(oral)zroutezonly
B. Bypasszthezhepaticzcirculation
C. Arezrapidlyzmetabolizedzbyzthezliverzandzmayzhavezlittlezifzanyzdesiredzaction
D. Arezconvertedzbyzthezliverztozmorezactivezandzfat-solublezforms
ANS:z C PTS:z 1

3. Thezroutezofzexcretionzofzazvolatilezdrugzwillzlikelyzbe:
A. Thezkidneys
B. Thezlungs
C. Thezbilezandzfeces
D. Thezskin
ANS:z B PTS:z 1

4. Medroxyprogesteronez(DepozProvera)ziszprescribedzIMztozcreatezazstoragezreservoirzofzthezd
rug.zStoragezreservoirs:
A. Assurezthatzthezdrugzwillzreachzitszintendedztargetztissue
B. Arezthezreasonzforzgivingzloadingzdoses
C. Increasezthezlengthzofztimezazdrugziszavailablezandzactive
D. Arezmostzcommonzinzcollagenztissues
ANS:z C PTS:z 1

5. ThezNPzchoosesztozgivezcephalexinzeveryz8zhourszbasedzonzknowledgezofzthezdrug’s:
A. Propensityztozgoztoztheztargetzreceptor
B. Biologicalzhalf-life
C. Pharmacodynamics
D. Safetyzandzsidezeffects
ANS:z B PTS:z 1

6. Azithromycinzdosingzrequireszthezfirstzday’szdosezbeztwicezthosezofzthezotherz4zdayszofzthezpr
escription.zThisziszconsideredzazloadingzdose.zAzloadingzdose:
A. Rapidlyzachieveszdrugzlevelszinztheztherapeuticzrange
B. Requireszfourztozfivezhalf-livesztozattain
C. Iszinfluencedzbyzrenalzfunction

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D. Iszdirectlyzrelatedztozthezdrugzcirculatingztoztheztargetztissues
ANS:z A PTS:z 1

7. Thezpointzinztimezonzthezdrugzconcentrationzcurvezthatzindicateszthezfirstzsignzofzaztherapeuticzef
fectziszthe:
A. Minimumzadversezeffectzlevel
B. Peakzofzaction
C. Onsetzofzaction
D. Therapeuticzrange
ANS:z C PTS:z 1

8. Phenytoinzrequireszaztroughzlevelzbezdrawn.zPeakzandztroughzlevelszarezdone:
A. Whenzthezdrugzhaszazwideztherapeuticzrange
B. Whenzthezdrugzwillzbezadministeredzforzazshortztimezonly
C. Whenzthereziszazhighzcorrelationzbetweenzthezdosezandzsaturationzofzreceptorzsites
D. Tozdeterminezifzazdrugziszinztheztherapeuticzrange
ANS:z D PTS:z 1

9. Azlaboratoryzresultzindicateszthezpeakzlevelzforzazdrugziszabovezthezminimumztoxiczc
oncentration.zThiszmeanszthatzthe:
A. Concentrationzwillzproduceztherapeuticzeffects
B. Concentrationzwillzproducezanzadversezresponse
C. Timezbetweenzdoseszmustzbezshortened
D. Durationzofzactionzofzthezdrugzisztoozlong
ANS:z B PTS:z 1

10. Drugszthatzarezreceptorzagonistszmayzdemonstratezwhatzproperty?
A. Irreversiblezbindingztozthezdrugzreceptorzsite
B. Up-regulationzwithzchroniczuse
C. Desensitizationzorzdown-regulationzwithzcontinuouszuse
D. Inversezrelationshipzbetweenzdrugzconcentrationzandzdrugzaction
ANS:z C PTS:z 1

11. Drugszthatzarezreceptorzantagonists,zsuchzaszbetazblockers,zmayzcause:
A. Down-regulationzofzthezdrugzreceptor
B. Anzexaggeratedzresponsezifzabruptlyzdiscontinued
C. Partialzblockadezofzthezeffectszofzagonistzdrugs
D. Anzexaggeratedzresponseztozcompetitivezdrugzagonists
ANS:z B PTS:z 1

12. Factorszthatzaffectzgastriczdrugzabsorptionzinclude:
A. Liverzenzymezactivity
B. Protein-bindingzpropertieszofzthezdrugzmolecule
C. Lipidzsolubilityzofzthezdrug
D. Abilityztozchewzandzswallow
ANS:z C PTS:z 1