PRIMARY CARE-COMPS NM717 EXAM QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST
UPDATE
Estrogen common side effects
breast tenderness, bloating, mood swings, decreased sex drive, head aches
Estrogen-dangerous side effects
blood clots
stroke
endometrial cancer
low estrogen
painful sex
absent periods
hot flashes
Progestin side effects
dizziness
water retention
weight gain
Antibiotics and COCs
Not with Rifampin and Griseofulvin
-think TB
-think ring worm, athlete's foot, and jock itch
,-increase hepatic enzyme inducer-reduces effectiveness of COCs
COCs and anticonvulsants
-decreases effectiveness of anticonvulsants
-some are impacted and some aren't--always run drug-to-drug interactions
-may be able to just increase dose during active days
Antiretrovirals and COCs
-some increase estrogen and some decrease
-may increase risk of stroke or lead to unintended pregnancies
Drug levels increased by COCs
Theophylline [asthma]-increased jitteriness
Valium [anxiety]-increased sedation
TCAs [depression]-overdose that's hard to reverse
Lithium [antipsychotic]
Drosperinone
Yaz or Yazmin
can interact with HTN meds/heparin/NSAIDS and cause hyperkalemia
-check potassium level midway through first cycle
COCs and St. John's Wort
,decreases level of COCs=unintended pregnancy
Big inducer of hormone=decreased levels circulating
Side effects
can be positive or negative
Adverse effect
negative side effect
Precautions
clinical implications
NOT contraindications, but should inform thoughts about risks and benefits
How serious is condition we've treated
Contraindications
ABSOLUTE-don't do it
Relative Contraindications
Applies to all but a few unusual circumstances
i.e Tetracycline for Rocky Mountain Spotted Fever in child under 8
Black Box Warning
Serious known adverse reaction
or
Adverse Effect may be mitigated by avoid clinical application
, or
FDA approved only for specific situations
Does not imply not using drug
Agonist
causes full effect on receptor
blocks other agonists from activating receptor
Partial Agonist
Causes partial effect on receptor
blocks other agonists from activating receptor
Antagonist
Blocks receptor but causes no effect
Most Common ER visit for adverse drug effects
Anticoagulants
Common adverse drug interactions
warfarin
SSRIs
fluoroquinolones [resp,UTIs]
cholinesterase inhibitors
trimethoprim-sulfamethoxazole (bactrim) (TMP-SMX)
NSAIDs
ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST
UPDATE
Estrogen common side effects
breast tenderness, bloating, mood swings, decreased sex drive, head aches
Estrogen-dangerous side effects
blood clots
stroke
endometrial cancer
low estrogen
painful sex
absent periods
hot flashes
Progestin side effects
dizziness
water retention
weight gain
Antibiotics and COCs
Not with Rifampin and Griseofulvin
-think TB
-think ring worm, athlete's foot, and jock itch
,-increase hepatic enzyme inducer-reduces effectiveness of COCs
COCs and anticonvulsants
-decreases effectiveness of anticonvulsants
-some are impacted and some aren't--always run drug-to-drug interactions
-may be able to just increase dose during active days
Antiretrovirals and COCs
-some increase estrogen and some decrease
-may increase risk of stroke or lead to unintended pregnancies
Drug levels increased by COCs
Theophylline [asthma]-increased jitteriness
Valium [anxiety]-increased sedation
TCAs [depression]-overdose that's hard to reverse
Lithium [antipsychotic]
Drosperinone
Yaz or Yazmin
can interact with HTN meds/heparin/NSAIDS and cause hyperkalemia
-check potassium level midway through first cycle
COCs and St. John's Wort
,decreases level of COCs=unintended pregnancy
Big inducer of hormone=decreased levels circulating
Side effects
can be positive or negative
Adverse effect
negative side effect
Precautions
clinical implications
NOT contraindications, but should inform thoughts about risks and benefits
How serious is condition we've treated
Contraindications
ABSOLUTE-don't do it
Relative Contraindications
Applies to all but a few unusual circumstances
i.e Tetracycline for Rocky Mountain Spotted Fever in child under 8
Black Box Warning
Serious known adverse reaction
or
Adverse Effect may be mitigated by avoid clinical application
, or
FDA approved only for specific situations
Does not imply not using drug
Agonist
causes full effect on receptor
blocks other agonists from activating receptor
Partial Agonist
Causes partial effect on receptor
blocks other agonists from activating receptor
Antagonist
Blocks receptor but causes no effect
Most Common ER visit for adverse drug effects
Anticoagulants
Common adverse drug interactions
warfarin
SSRIs
fluoroquinolones [resp,UTIs]
cholinesterase inhibitors
trimethoprim-sulfamethoxazole (bactrim) (TMP-SMX)
NSAIDs
