BSN 315 PHARM EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
Which statement explains the action of carbidopa-levodopa?
Carbidopa prevents levodopa decarboxylation in the periphery, resulting in more
levodopa being transported to the brain.
With the use of carbidopa, less levodopa is needed because more levodopa becomes
available for use within the brain. Carbidopa has no therapeutic effect of its own.
Through which route is carbidopa-levodopa excreted?
Urine
Carbidopa-levodopa is excreted in the urine as metabolites after metabolism occurs in
the periphery by decarboxylase enzymes and catechol-o-methyltransferase (COMT).
Match the class of drugs used to treat Parkinson's disease with its mechanism of
action.
Affect dopamine content of the brain-Dopaminergics
Stimulate dopamine receptors of nerve cells in the brain-Dopamine agonists
Inhibit activity of acetylcholine-Anticholinergics
Inhibit activity of monoamine oxidase (MAO)-MAO-B inhibitors
Which statement correctly explains the action of rivastigmine?
Increases availability of acetylcholine in the neuron receptors
Rivastigmine effectively penetrates the central nervous system and increases the
, availability of acetylcholine in the neuron receptors. The result is improved cognitive
function in patients with mild to moderate Alzheimer's disease.
Which route of administration for rivastigmine results in a peak concentration
between 8 and 16 hours?
Transdermal
Transdermal applications of rivastigmine peak between 8 and 16 hours. This allows for
less frequent dosing.
Which side effects would the nurse teach Mrs. Hill to expect while taking
rivastigmine?
Nausea
Nausea is a potential side effect of rivastigmine. It is one of the most common side
effects of this medication and can be reduced by taking the medication with food.
Severe nausea should be reported immediately because it may indicate a more serious
adverse effect such as hepatotoxicity or cholinergic crisis.
Diarrhea
Diarrhea is a potential side effect of rivastigmine. Gastric upset is one of the most
common side effects of this medication and can be reduced by taking the medication
with food. The patient should be sure to stay well hydrated if diarrhea occurs.
Anorexia
Anorexia is a potential side effect of rivastigmine. Gastric upset is one of the most
common side effects of this medication.
COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
Which statement explains the action of carbidopa-levodopa?
Carbidopa prevents levodopa decarboxylation in the periphery, resulting in more
levodopa being transported to the brain.
With the use of carbidopa, less levodopa is needed because more levodopa becomes
available for use within the brain. Carbidopa has no therapeutic effect of its own.
Through which route is carbidopa-levodopa excreted?
Urine
Carbidopa-levodopa is excreted in the urine as metabolites after metabolism occurs in
the periphery by decarboxylase enzymes and catechol-o-methyltransferase (COMT).
Match the class of drugs used to treat Parkinson's disease with its mechanism of
action.
Affect dopamine content of the brain-Dopaminergics
Stimulate dopamine receptors of nerve cells in the brain-Dopamine agonists
Inhibit activity of acetylcholine-Anticholinergics
Inhibit activity of monoamine oxidase (MAO)-MAO-B inhibitors
Which statement correctly explains the action of rivastigmine?
Increases availability of acetylcholine in the neuron receptors
Rivastigmine effectively penetrates the central nervous system and increases the
, availability of acetylcholine in the neuron receptors. The result is improved cognitive
function in patients with mild to moderate Alzheimer's disease.
Which route of administration for rivastigmine results in a peak concentration
between 8 and 16 hours?
Transdermal
Transdermal applications of rivastigmine peak between 8 and 16 hours. This allows for
less frequent dosing.
Which side effects would the nurse teach Mrs. Hill to expect while taking
rivastigmine?
Nausea
Nausea is a potential side effect of rivastigmine. It is one of the most common side
effects of this medication and can be reduced by taking the medication with food.
Severe nausea should be reported immediately because it may indicate a more serious
adverse effect such as hepatotoxicity or cholinergic crisis.
Diarrhea
Diarrhea is a potential side effect of rivastigmine. Gastric upset is one of the most
common side effects of this medication and can be reduced by taking the medication
with food. The patient should be sure to stay well hydrated if diarrhea occurs.
Anorexia
Anorexia is a potential side effect of rivastigmine. Gastric upset is one of the most
common side effects of this medication.
