BSN 315 HESI STUDY SET EXAM ACTUAL QUESTIONS WITH
COMPLETE VERIFIED CORRECT ANSWERS GRADED A++
Which medication is contraindicated in a patient receiving selegiline for
Parkinson's disease?
Aspirin
Lisinopril
Ranitidine
Meperidine
Meperidine
Rationale: Concomitant admisitration of a monoamine oxidase-B (MAO-B) inhibitor such
as selegikine with meperidine is contraindicated because it can cause serotonin
syndrome as a result of enhanced serotonin activity in the brain.
Which drug is used as an adjunct therapy with levodopa/carbidopa to treat
Parkinson's disease?
Selegiline
Entacapone
Benztropine
Amantadine
Selegiline
Rationale: Selegiline is a selective type B monoamine oxidase inhibitor that is useful as
an adjunct therapy with levodopa/carbidopa to decrease fluctuating symptoms.
,Which class of drugs is administered to treat on-off phenomenon in a patient with
Parkinson's?
Dopamine Modulators
Anticholinergic drugs
Catechol O-methyltransferase (COMT)
Indirect-acting dopamine receptor agonists
COMT
Rationale: COMT drugs are useful for treating the on-off phenomenon in Parkinson's,
which is caused by fluctuations in dopamine concentrations. These drugs inhibit the
enzyme catalyzing the breakdown of catecholamines, thereby maintaining uniform
concentrations of dopamine.
Which symptoms are associated with parkinson's?
Rigidity
Tremors
Seizures
Tachycardia
Bradykinesia
Rigidity, tremors, bradykinesia
What is the main anatomic area of the brain that is affected in a patient with
Parkinson's disease?
Thalamus
Cerebellum
, Globus Pallidus
Substantia nigra
Substantia nigra
Rationale: The substantia nigra is a part of the extrapyramidal system, which is involved
in motor function, including posture, muscle tone, and smooth muscle activity.
Dopamine depletion in this area causes PD
What is the goal of pharmacological therapy in the treatment of Parkinson's?
Balance cholinergic and dopaminergic activity in the brain.
Rationale: PD results from a decrease in dopaminergic (Inhibitory) activity leaving an
imbalance with too much cholinergic (excitatory) activity.
The healthcare provider orders entacapone 400 mg by mouth (PO) every 6 hours.
The nurse notes that the total dose given in a 24-hour period would be what
amount?
1600mg
A patient is in status epilepticus. What is an appropriate nursing action?
Apply restraints
Hold the patient's limbs steady
Administer intravenous pain medicine
Administer intravenous antiepileptic drug therapy.
Administer intravenous antiepileptic drug therapy
Rationale: During status epilepticus, the patient is unable to swallow medications, and
the appropriate treatment is to administer intravenous drug therapy to stop the seizure.
COMPLETE VERIFIED CORRECT ANSWERS GRADED A++
Which medication is contraindicated in a patient receiving selegiline for
Parkinson's disease?
Aspirin
Lisinopril
Ranitidine
Meperidine
Meperidine
Rationale: Concomitant admisitration of a monoamine oxidase-B (MAO-B) inhibitor such
as selegikine with meperidine is contraindicated because it can cause serotonin
syndrome as a result of enhanced serotonin activity in the brain.
Which drug is used as an adjunct therapy with levodopa/carbidopa to treat
Parkinson's disease?
Selegiline
Entacapone
Benztropine
Amantadine
Selegiline
Rationale: Selegiline is a selective type B monoamine oxidase inhibitor that is useful as
an adjunct therapy with levodopa/carbidopa to decrease fluctuating symptoms.
,Which class of drugs is administered to treat on-off phenomenon in a patient with
Parkinson's?
Dopamine Modulators
Anticholinergic drugs
Catechol O-methyltransferase (COMT)
Indirect-acting dopamine receptor agonists
COMT
Rationale: COMT drugs are useful for treating the on-off phenomenon in Parkinson's,
which is caused by fluctuations in dopamine concentrations. These drugs inhibit the
enzyme catalyzing the breakdown of catecholamines, thereby maintaining uniform
concentrations of dopamine.
Which symptoms are associated with parkinson's?
Rigidity
Tremors
Seizures
Tachycardia
Bradykinesia
Rigidity, tremors, bradykinesia
What is the main anatomic area of the brain that is affected in a patient with
Parkinson's disease?
Thalamus
Cerebellum
, Globus Pallidus
Substantia nigra
Substantia nigra
Rationale: The substantia nigra is a part of the extrapyramidal system, which is involved
in motor function, including posture, muscle tone, and smooth muscle activity.
Dopamine depletion in this area causes PD
What is the goal of pharmacological therapy in the treatment of Parkinson's?
Balance cholinergic and dopaminergic activity in the brain.
Rationale: PD results from a decrease in dopaminergic (Inhibitory) activity leaving an
imbalance with too much cholinergic (excitatory) activity.
The healthcare provider orders entacapone 400 mg by mouth (PO) every 6 hours.
The nurse notes that the total dose given in a 24-hour period would be what
amount?
1600mg
A patient is in status epilepticus. What is an appropriate nursing action?
Apply restraints
Hold the patient's limbs steady
Administer intravenous pain medicine
Administer intravenous antiepileptic drug therapy.
Administer intravenous antiepileptic drug therapy
Rationale: During status epilepticus, the patient is unable to swallow medications, and
the appropriate treatment is to administer intravenous drug therapy to stop the seizure.
