BSN315 SHERPATH WEEK 8 CHAPTER 47, CALCIUM CHANNEL
BLOCKER THERAPY EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED
Notes on Calcium channel blockers, CCBs are an effective and safe class of
drugs that have few adverse effects, which is why they are often a first line of
treatment for hypertension. Because these drugs are widely prescribed for the
treatment
of hypertension, angina, and cardiac dysrhythmias, nurses must be knowledgeable
regarding administration, side effects, and evaluation of effectiveness.
Best Practice Pearls
There are only two nondihydropyridines: verapamil and diltiazem.
The other CCBs are all dihydropyridines and end in -pine (nifedipine, amlodipine,
felodipine). This helps in differentiating CCBs.
Pharmacokinetics of Calcium Channel Blockers, Nifedipine. CCBs are highly
bound to protein; however, they have a short half-life.
Nifedipine
Absorption Well absorbed
Distribution Protein bound
Metabolism In the liver
Excretion In urine and feces
, Pharmacokinetics of Calcium Channel Blocker, Amlodipine.
CCBs are highly bound to protein; however, they have a short half-life.
Amlodipine.
Absorption Well absorbed
Distribution Protein bound
Metabolism In the liver
Excretion In urine
Pharmacokinetics of Calcium Channel Blockers, Verapamil. CCBs are highly
bound to protein; however, they have a short half-life.
Verapamil.
Absorption Well absorbed
Distribution Protein bound 90%
Metabolism In the liver
Excretion In Urine
Pharmacokinetics of Calcium Channel Blockers, Diltiazem. CCBs are highly
bound to protein; however, they have a short half-life.
Diltiazem
Absorption Well absorbed
Distribution Protein bound 70%-80%; in breast milk
Metabolism In the liver
Excretion In urine and feces
Pharmacodynamics of Calcium Channel Blockers. Pharmacodynamics of Calcium
Channel Blockers CCBs work to block calcium from crossing the cell membrane
BLOCKER THERAPY EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED
Notes on Calcium channel blockers, CCBs are an effective and safe class of
drugs that have few adverse effects, which is why they are often a first line of
treatment for hypertension. Because these drugs are widely prescribed for the
treatment
of hypertension, angina, and cardiac dysrhythmias, nurses must be knowledgeable
regarding administration, side effects, and evaluation of effectiveness.
Best Practice Pearls
There are only two nondihydropyridines: verapamil and diltiazem.
The other CCBs are all dihydropyridines and end in -pine (nifedipine, amlodipine,
felodipine). This helps in differentiating CCBs.
Pharmacokinetics of Calcium Channel Blockers, Nifedipine. CCBs are highly
bound to protein; however, they have a short half-life.
Nifedipine
Absorption Well absorbed
Distribution Protein bound
Metabolism In the liver
Excretion In urine and feces
, Pharmacokinetics of Calcium Channel Blocker, Amlodipine.
CCBs are highly bound to protein; however, they have a short half-life.
Amlodipine.
Absorption Well absorbed
Distribution Protein bound
Metabolism In the liver
Excretion In urine
Pharmacokinetics of Calcium Channel Blockers, Verapamil. CCBs are highly
bound to protein; however, they have a short half-life.
Verapamil.
Absorption Well absorbed
Distribution Protein bound 90%
Metabolism In the liver
Excretion In Urine
Pharmacokinetics of Calcium Channel Blockers, Diltiazem. CCBs are highly
bound to protein; however, they have a short half-life.
Diltiazem
Absorption Well absorbed
Distribution Protein bound 70%-80%; in breast milk
Metabolism In the liver
Excretion In urine and feces
Pharmacodynamics of Calcium Channel Blockers. Pharmacodynamics of Calcium
Channel Blockers CCBs work to block calcium from crossing the cell membrane
