Chapter 01: Introduction to Pathophysiology
x x x x
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
x x x x x x x x x x
MULTIPLExCHOICE
1. Whichxofxthexfollowingxwouldxbexthexmostxlikelyxcausexofxanxi
atrogenicxdisease?
a. Anxinheritedxdisorder
b. Axcombinationxofxspecificxetiologicalxfactors
c. Anxunwantedxeffectxofxaxprescribedxdrug
d. Prolongedxexposurextoxtoxicxchemicalsxinxthexenvironment
ANS:x C
2. Thexmanifestationsxofxaxdiseasexarexbestxdefinedxasxthe
a. subjectivexfeelingsxofxdiscomfortxduringxaxchronicxillness.
b. signsxandxsymptomsxofxaxdisease.
c. factorsxthatxprecipitatexanxacutexepisodexofxaxchronicxillness.
d. earlyxindicatorsxofxthexprodromalxstagexofxinfection.
ANS:x B
3. Thexbestxdefinitionxofxthextermxprognosisxisxthe
a. precipitatingxfactorsxcausingxanxacutexepisode.
b. numberxofxremissionsxtoxbexexpectedxduringxthexcoursexofxaxchronicxillness.
c. predictedxoutcomexorxlikelihoodxofxrecoveryxfromxaxspecificxdisease.
d. exacerbationsxoccurringxduringxchronicxillness.
ANS:x C
4. Whichxofxthexfollowingxisxconsideredxaxsystemicxsignxofxdisease?
a. Swellingxofxthexknee
b. Fever
c. Painxinxthexneck
d. Redxrashxonxthexface
ANS:x B
5. Etiologyxisxdefinedxasxthexstudyxofxthe
a. causesxofxaxdisease.
b. coursexofxaxdisease.
c. expectedxcomplicationsxofxaxdisease.
d. manifestationsxofxaxdisease.
ANS:x A
6. Axtypexofxcellularxadaptationxinxwhichxtherexisxaxdecreasexinxcellxsizexisxreferredxtoxas
a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS:x D
7. Axchangexinxaxtissuexmarkedxbyxcellsxthatxvaryxinxsizexandxshapexandxshowxincreasedxmitoticxfi
guresxwouldxbexcalled
,TestxBankxForxGould'sxPathophysiologyxforxthexHealthxProfessionsx7thxEditionxVanMeter 2
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS:x C
8. Axdeficitxofxoxygenxinxthexcellsxusuallyxduextoxrespiratoryxorxcirculatoryxproblemsxisxcalled
a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS:x B
9. Whenxaxgroupxofxcellsxinxthexbodyxdies,xthexchangexisxcalled
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS:x D
10. Rigorousxweightlifting/bodyxbuildingxregimensxmayxresultxinxthexskeletalxmusclexcellsxu
ndergoing
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS:x A
11. Thextermxcancerxrefersxto
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignantxneoplasm.
ANS:x D
12. Toxwhichxofxthexfollowingxdoesxthextermxapoptosisxrefer?
a. Increasedxratexofxmitosisxbyxcertainxcells
b. Ischemicxdamagextoxcells
c. Liquefactionxofxnecroticxtissue
d. Preprogrammedxcellxself-destruction
ANS:x D
13. WhichxofxthexfollowingxstatementsxisxTRUE?
a. AlterationxofxDNAxdoesxnotxchangexcellxfunction.
b. Damagedxcellsxmayxbexablextoxrepairxthemselves.
c. Allxtypesxofxcellsxdiexatxthexsamexrate.
d. Mildxischemiaxcausesximmediatexcellxdeath.
ANS:x B
14. Caseationxnecrosisxrefersxtoxanxareaxwhere
a. cellxproteinsxhavexbeenxdenatured.
,TestxBankxForxGould'sxPathophysiologyxforxthexHealthxProfessionsx7thxEditionxVanMeter 3
b. cellsxarexliquefiedxbyxenzymes.
c. deadxcellsxformxaxthickxcheesyxsubstance.
d. bacterialxinvasionxhasxoccurred.
ANS:x C
15. Routinexapplicationxofxsunxblockxtoxskinxwouldxbexanxexamplexof
a. anxiatrogenicxcausexofxcancer.
b. axpreventivexmeasure.
c. axprecipitatingxfactor.
d. axpredisposingxcondition.
ANS:x B
16. Axcircumstancexthatxcausesxaxsuddenxacutexepisodexofxaxchronicxdiseasextoxoccurxisxtermed
a. latentxstage.
b. predisposingxfactor.
c. incidence.
d. precipitatingxfactor.
ANS:x D
17. Thextermxhomeostasisxrefersxto
a. thexcausativexfactorsxinxaxparticularxdisease.
b. maintenancexofxaxstablexinternalxenvironment.
c. axconditionxthatxtriggersxanxacutexepisode.
d. axcollectionxofxsignsxandxsymptoms.
ANS:x B
18. Whichxtermxisxusedxtoxdescribexaxnewxandxsecondaryxorxadditionalxproblemxthatxarisesxafterxthexo
riginalxdiseasexhasxbeenxestablished?
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS:x D
19. Pathophysiologyxinvolvesxthexstudyxof
a. thexstructurexofxthexhumanxbody.
b. thexfunctionsxofxvariousxorgansxinxthexbody.
c. functionalxorxstructuralxchangesxresultingxfromxdiseasexprocesses.
d. variousxcellxstructuresxandxrelatedxfunctions.
ANS:x C
20. Whichxofxthexfollowingxisxthexbestxdefinitionxofxepidemiology?
a. Thexsciencexofxtrackingxthexoccurrencexandxdistributionxofxdiseases
b. Thexrelativexnumberxofxdeathsxresultingxfromxaxparticularxdisease
c. Identificationxofxaxspecificxdiseasexthroughxevaluationxofxsignsxandxsymptoms
d. Thexglobalxsearchxforxemergingxdiseases
ANS:x A
, TestxBankxForxGould'sxPathophysiologyxforxthexHealthxProfessionsx7thxEditionxVanMeter 4
21. Whichxofxthexfollowingxcanxcausexcellxinjuryxorxdeath?
1. Hypoxia
2. Exposurextoxexcessivexcold
3. Excessivexpressurexonxaxtissue
4. Chemicalxtoxins
a. 1,x2
b.xxx 2,x4
c. 1,x3,x4
d.x 1,x2,x3,x4
ANS:x D
22. AllxofxthexfollowingxarexpartxofxthexSevenxStepsxtoxHealthxEXCEPT:
a. Followxcancerxscreeningxguidelines.
b. Usexsunxblockxagentsxwheneverxexposed.
c. Participatexinxstrenuousxexercisexonxaxregularxdailyxbasis.
d. Choosexhighxfiber,xlowerxfatxfoods.
ANS:x C
23. Thextermxdiseasexrefersxto
a. thexperiodxofxrecoveryxandxreturnxtoxaxnormalxhealthyxstate.
b. axdeviationxfromxthexnormalxstatexofxhealthxandxfunction.
c. thextreatmentxmeasuresxusedxtoxpromotexrecovery.
d. axbasicxcollectionxofxsignsxandxsymptoms.
ANS:x B
24. Axcollectionxofxsignsxandxsymptoms,xoftenxaffectingxmorexthanxonexorganxorxsystem,xthatxu
suallyxoccurxtogetherxinxresponsextoxaxcertainxconditionxisxreferredxtoxasxa(an)
a. acutexdisease.
b. multiorganxdisorder.
c. syndrome.
d. manifestation.
ANS:x C
25. AllxofxthexfollowingxstatementsxarexcorrectxaboutxcellxdamagexEXCEPT:
a. Thexinitialxstagexofxcellxdamagexoftenxcausesxanxalterationxinxmetabolicxreactions.
b. Ifxthexfactorxcausingxthexdamagexisxremovedxquickly,xthexcellxmayxbexablextoxr
ecoverxandxreturnxtoxitsxnormalxstate.
c. Ifxthexnoxiousxfactorxremainsxforxanxextendedxperiodxofxtime,xthexdamagexbecomesxir
reversiblexandxthexcellxdies.
d. Initially,xcellxdamagexdoesxnotxchangexcellxmetabolism,xstructure,xorxfunction.
ANS:x D
26. Whichxofxthexfollowingxconditionsxdistinguishesxdoublexblindxstudiesxusedxinxhealthxresearch?
a. Neitherxthexmembersxofxthexcontrolxgroupxorxthexexperimentalxgroupxnorxthexpersonxa
dministeringxthextreatmentxknowsxwhoxisxreceivingxthexexperimentalxtherapy.
b. Bothxgroupsxofxresearchxsubjectsxandxthexpersonxadministeringxthextreatmentxknowxwhoxi
sxreceivingxthexexperimentalxtherapy.
c. Thexresearchxsubjectsxdoxnotxknow,xbutxthexpersonxadministeringxthextreatmentxk
nowsxwhoxisxreceivingxplaceboxorxstandardxtherapy.
d. Onlyxmembersxofxthexcontrolxgroupxknowxtheyxarexreceivingxstandardxtherapy.