Abrams' Clinical Drug Therapy: Rationales for Nursing
b b b b b b b
Practice 12th EditionFrandsen Test
b b b b
Bank b
,Abrams'bClinicalbDrugbTherapy:bRationalesbforbNursingbPracticeb12thbEditionbFrandsenbTestbBank
Chapterb 1b Theb Foundationb ofb Pharmacology:b Qualityb andb Safety
Abwomanbhasbbeenbprescribedbparoxetinebhydr
ochloride,bwhichbisbanbantidepressantbagentbad
ministeredbinbpillbform.bThebmedicationb isb adm
1.
inisteredb forb herb obsessive-
bcompulsiveb disorder.bThisb medicationb will
produceb whichb ofb theb followingb effects?
A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Feedback:
Drugsb thatb produceb systemicb effectsb areb takenbi
ntobthebbody,bcirculatedbthroughbthebbloodstrea
mb tob theirb sitesb ofb actionb inb variousbbodyb tissue
s,b andb eventuallyb eliminatedb frombthebbody.bCu
rativebagentsbarebgivenbtob curebabdiseasebproces
s.b Inbthisbcase,bparoxetinebhydrochlorideb willb c
ontrolb theb symptomsb butbnotb cureb theb disorder.b
Drugsb withb localb effects,bsuchbasbsunscreenbandb
localbanesthetics,bactbmainlybatbthebsitebofbappli
cation.bParoxetinebhydrochloridebisb notb admin
isteredbparenterally.b Parenteralb agentsb arebadmi
nisteredb subcutaneously,b intramuscularly,
orbintravenously.
Abpatientb hasb beenb prescribedb anb antibiotic.bT
hisbmedicationbisbabnaturallyboccurringbsubsta
2. nceb thatb hasb beenb chemicallyb modified.bWhatbi
sbanotherbnamebforbthisbtypebof
medication?
A) Syntheticb drug
B) Semisyntheticb drug
C) Biotechnologyb drug
D) Prototypeb drug
Ans: B
Feedback:
,Abrams'bClinicalbDrugbTherapy:bRationalesbforbNursingbPracticeb12thbEditionbFrandsenbTestbBank
Semisyntheticb drugsb (e.g.,b manyb antibiotics)bar
ebnaturallyb occurringb substancesbthatb havebbeen
b chemicallyb modified. b Syntheticb drugsb arebmore
bstandardizedbinbtheirbchemicalbcharacteristics,b
morebconsistentb inb theirbeffects,bandblessblikely
btob produceb allergicbreactions.b Biotechnologyb d
rugsbinvolvebmanipulatingb DNAbandb RNAban
dbrecombiningb genesb intob hybridb moleculesb tha
tbcanbbebinsertedbintoblivingborganisms.
Prototypebdrugsbarebthebfirstbdrugbofba
particularb groupb tob beb developed.
Abpatientb isb administeredb morphine.b Morphineb
isbabprototypicalbdrugbthatb canbbebclassifiedbinbd
3.
ifferentbways.bWhichbofbthebfollowing
classificationsb appliesb tob morphine?
A) Centralb nervousb systemb depressant
B) Centralb nervousb systemb stimulant
C) Anti-inflammatory
D) Antihypertensive
Ans: A
Feedback:
Drugsbarebclassifiedb accordingbtob theirbeffectsbo
nb particularb bodyb systems,b theirb therapeuticbuse
s,b andb theirb chemicalb characteristics.b Forbexam
ple,bmorphinebcanbbebclassifiedbasbabcentralbner
vousbsystembdepressantbandbabnarcoticb orb opioi
db analgesic.bAbcentralb nervousbsystembstimulant
b increasesb attentionb andbraisesbmood.bAnb anti-
inflammatorybagentbdecreasesbinflammationb atb
theb siteb ofbtissueb orbjointb inflammation.bAnb anti
hypertensiveb agent
reducesb bloodb pressure.
Abpatientbisbadministeredbamoxicillinb(Amoxi
l).bThebgenericbnamebofbthisbmedicationb indic
4.
atesb thatb itb belongsb tob which
drugb group?
A) Selectiveb serotoninb reuptakeb inhibitors
B) Diuretics
C) Penicillins
D) ACEb inhibitors
Ans: C
, Abrams'bClinicalbDrugbTherapy:bRationalesbforbNursingbPracticeb12thbEditionbFrandsenbTestbBank
Feedback:
Thebgenericbnameboftenbindicatesbthebdrugbgro
upb (e.g.,b drugsb withb genericb namesb endingbinb “
cillin”b areb penicillins).b Selectiveb serotoninbreup
takeb inhibitorsb areb medicationsb thatb havebantid
epressantbeffects;bSSRIbisbabbroadbclassificatio
n,bnotbab genericbname.bDiureticsbarebmedicatio
nsbthatb increaseburineb output;bdiureticbisb abbroa
db classification,b notbab genericbname.bACEb inhib
itorb isb theb broadbclassificationb forb theb angioten
sin-converting
enzymeb inhibitors,b notb theb genericb name.
Thebadministrationbofbdiphenhydramineb(Benadr
yl),bwhichbisbanbover-the-
5.
counterbmedication,b isb regulatedb byb whichb gove
rnment
agency?
A) PublicbHealthbService
B) FederalbTradeb Commission
Occupationalb Safetyb andb Health
C)
Administration
D) Foodb andb DrugbAdministration
Ans: D
Feedback:
Theb Foodb andb DrugbAdministrationb approvesbd
rugsbforbover-the-
counterbavailability,bincludingbthebtransferbofbd
rugsbfrombprescriptionb tob OTCb status,b andb may
b requirebclinicalb trialsb tob determineb theb safetyb a
ndbeffectivenessb ofb OTCb use.bTheb Publicb Healt
hbServicebisbregulatedb bybthebstateb tobmaintainbt
hebhealthb ofb individualb citizensb ofb theb state.bTh
eb FederalbTradebCommissionbregulatesbimports
b andb exportsb throughoutb theb nation.
Theb Occupationalb Safetyb andb Health
Administrationb regulatesb safetyb withinb thebwor
kplace.
Theb administrationb ofb anabolicb steroidsb is
6.
regulatedb byb whichb ofb theb followingb laws?
A) Theb Food,b Drug,b andb CosmeticbActb ofb 1938
Theb Comprehensiveb DrugbAbuseb Prevention
B)
andb ControlbAct
C) ThebHarrisonb NarcoticbAct