Course
NSG 124/ NSG124
1. Question:
What is the primary action of beta-blockers in the body?
a) Increase heart rate
b) Decrease blood pressure
c) Increase the release of insulin
d) Relax smooth muscles
Answer:
b) Decrease blood pressure
Rationale:
Beta-blockers primarily act by blocking beta receptors in the heart, which decreases the heart
rate and the force of contraction. This leads to a decrease in blood pressure and reduced
workload on the heart, making them effective in managing hypertension and heart failure.
2. Question:
Which of the following medications is commonly used to treat anaphylaxis?
a) Aspirin
b) Epinephrine
c) Diphenhydramine
d) Ibuprofen
Answer:
b) Epinephrine
Rationale:
Epinephrine is the first-line treatment for anaphylaxis because it quickly reverses the life-
threatening symptoms, including bronchoconstriction and vasodilation, by stimulating alpha and
beta receptors, leading to vasoconstriction and bronchodilation.
3. Question:
A patient is prescribed digoxin. What is the most important assessment before administering this
medication?
a) Blood pressure
b) Respiratory rate
,c) Heart rate
d) Temperature
Answer:
c) Heart rate
Rationale:
Before administering digoxin, it is critical to assess the patient's heart rate. Digoxin slows the
heart rate by inhibiting the Na+/K+ ATPase pump, which may lead to bradycardia. If the heart
rate is below 60 beats per minute, the medication should not be administered, and the healthcare
provider should be contacted.
4. Question:
Which class of drugs is primarily used to manage type 2 diabetes by increasing insulin
sensitivity?
a) Sulfonylureas
b) Biguanides
c) Thiazolidinediones
d) Alpha-glucosidase inhibitors
Answer:
b) Biguanides
Rationale:
Biguanides, particularly metformin, work by decreasing hepatic glucose production and
improving insulin sensitivity in peripheral tissues. This class is often used as a first-line treatment
for type 2 diabetes.
5. Question:
Which of the following is a common side effect of ACE inhibitors (Angiotensin-Converting
Enzyme Inhibitors)?
a) Hyperkalemia
b) Hypokalemia
c) Tachycardia
d) Weight loss
Answer:
a) Hyperkalemia
Rationale:
ACE inhibitors, such as lisinopril, inhibit the conversion of angiotensin I to angiotensin II,
,leading to vasodilation. They also reduce aldosterone secretion, which can lead to an increase in
potassium levels in the blood, resulting in hyperkalemia.
6. Question:
Which of the following is a contraindication for the use of NSAIDs (Non-Steroidal Anti-
Inflammatory Drugs)?
a) Asthma
b) Hypertension
c) Peptic ulcer disease
d) Diabetes
Answer:
c) Peptic ulcer disease
Rationale:
NSAIDs can irritate the gastrointestinal tract, leading to the development of ulcers or worsening
existing peptic ulcer disease. They inhibit cyclooxygenase (COX), reducing prostaglandin
production, which is important for maintaining the protective lining of the stomach.
7. Question:
What is the mechanism of action of warfarin?
a) Increases platelet aggregation
b) Inhibits vitamin K-dependent clotting factors
c) Increases fibrinolysis
d) Enhances the activity of thrombin
Answer:
b) Inhibits vitamin K-dependent clotting factors
Rationale:
Warfarin is an anticoagulant that works by inhibiting the action of vitamin K, which is essential
for synthesizing clotting factors II, VII, IX, and X in the liver. This reduces the blood's ability to
form clots.
8. Question:
What is the primary purpose of administering naloxone to a patient?
a) Reversal of opioid overdose
b) Treatment of anxiety
, c) Pain relief
d) Treatment of hypoglycemia
Answer:
a) Reversal of opioid overdose
Rationale:
Naloxone is an opioid antagonist that rapidly reverses the effects of opioid overdose, including
respiratory depression and sedation. It binds to opioid receptors in the brain, displacing the
opioid and reversing its effects.
9. Question:
Which of the following is the most important nursing intervention when administering a
chemotherapy drug?
a) Monitor blood glucose levels
b) Assess for signs of infection
c) Encourage fluid intake
d) Check for blood pressure changes
Answer:
b) Assess for signs of infection
Rationale:
Chemotherapy drugs can suppress the immune system, making patients more susceptible to
infections. It is crucial to monitor for signs of infection, such as fever, chills, or sore throat, and
notify the healthcare provider immediately if they occur.
10. Question:
Which of the following medications is a commonly prescribed treatment for depression and
anxiety disorders?
a) Prednisone
b) Fluoxetine
c) Propranolol
d) Lorazepam
Answer:
b) Fluoxetine
Rationale:
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed to treat
depression and anxiety disorders. SSRIs work by increasing the level of serotonin in the brain,
which helps improve mood and reduce anxiety.