Chapter 01: Introduction to Pathophysiology
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VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
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MULTIPLEuCHOICE
1. Whichuofutheufollowinguwouldubeutheumostulikelyucauseuofuanui
atrogenicudisease?
a. Anuinheritedudisorder
b. Aucombinationuofuspecificuetiologicalufactors
c. Anuunwantedueffectuofuauprescribedudrug
d. Prolongeduexposureutoutoxicuchemicalsuinutheuenvironment
ANS:u C
2. Theumanifestationsuofuaudiseaseuareubestudefineduasuthe
a. subjectiveufeelingsuofudiscomfortuduringuauchronicuillness.
b. signsuandusymptomsuofuaudisease.
c. factorsuthatuprecipitateuanuacuteuepisodeuofuauchronicuillness.
d. earlyuindicatorsuofutheuprodromalustageuofuinfection.
ANS:u B
3. Theubestudefinitionuofutheutermuprognosisuisuthe
a. precipitatingufactorsucausinguanuacuteuepisode.
b. numberuofuremissionsutoubeuexpecteduduringutheucourseuofuauchronicuillness.
c. predicteduoutcomeuorulikelihooduofurecoveryufromuauspecificudisease.
d. exacerbationsuoccurringuduringuchronicuillness.
ANS:u C
4. Whichuofutheufollowinguisuconsidereduausystemicusignuofudisease?
a. Swellinguofutheuknee
b. Fever
c. Painuinutheuneck
d. Redurashuonutheuface
ANS:u B
5. Etiologyuisudefineduasutheustudyuofuthe
a. causesuofuaudisease.
b. courseuofuaudisease.
c. expecteducomplicationsuofuaudisease.
d. manifestationsuofuaudisease.
ANS:u A
6. Autypeuofucellularuadaptationuinuwhichuthereuisuaudecreaseuinucellusizeuisureferredutouas
a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS:u D
7. Auchangeuinuautissueumarkedubyucellsuthatuvaryuinusizeuandushapeuandushowuincreasedumitoticufi
guresuwouldubeucalled
,TestuBankuForuGould'suPathophysiologyuforutheuHealthuProfessionsu7thuEditionuVanMeter 2
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS:u C
8. Audeficituofuoxygenuinutheucellsuusuallyudueutourespiratoryuorucirculatoryuproblemsuisucalled
a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS:u B
9. Whenuaugroupuofucellsuinutheubodyudies,utheuchangeuisucalled
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS:u D
10. Rigorousuweightlifting/bodyubuildinguregimensumayuresultuinutheuskeletalumuscleucellsu
undergoing
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS:u A
11. Theutermucancerurefersuto
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignantuneoplasm.
ANS:u D
12. Touwhichuofutheufollowingudoesutheutermuapoptosisurefer?
a. Increasedurateuofumitosisubyucertainucells
b. Ischemicudamageutoucells
c. Liquefactionuofunecroticutissue
d. Preprogrammeducellu self-destruction
ANS:u D
13. WhichuofutheufollowingustatementsuisuTRUE?
a. AlterationuofuDNAudoesunotuchangeucellufunction.
b. Damageducellsumayubeuableutourepairuthemselves.
c. Allutypesuofucellsudieuatutheusameurate.
d. Milduischemiaucausesuimmediateucelludeath.
ANS:u B
14. Caseationunecrosisurefersutouanuareauwhere
a. celluproteinsuhaveubeenudenatured.
,TestuBankuForuGould'suPathophysiologyuforutheuHealthuProfessionsu7thuEditionuVanMeter 3
b. cellsuareuliquefiedubyuenzymes.
c. deaducellsuformuauthickucheesyusubstance.
d. bacterialuinvasionuhasuoccurred.
ANS:u C
15. Routineuapplicationuofusunublockutouskinuwouldubeuanuexampleuof
a. anuiatrogenicucauseuofucancer.
b. aupreventiveumeasure.
c. auprecipitatingufactor.
d. aupredisposingucondition.
ANS:u B
16. Aucircumstanceuthatucausesuausuddenuacuteuepisodeuofuauchronicudiseaseutouoccuruisutermed
a. latentustage.
b. predisposingufactor.
c. incidence.
d. precipitatingufactor.
ANS:u D
17. Theutermuhomeostasisurefersuto
a. theucausativeufactorsuinuauparticularudisease.
b. maintenanceuofuaustableuinternaluenvironment.
c. auconditionuthatutriggersuanuacuteuepisode.
d. aucollectionuofusignsuandusymptoms.
ANS:u B
18. Whichutermuisuusedutoudescribeuaunewuandusecondaryuoruadditionaluproblemuthatuarisesuafterutheuo
riginaludiseaseuhasubeenuestablished?
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS:u D
19. Pathophysiologyuinvolvesutheustudyuof
a. theustructureuofutheuhumanubody.
b. theufunctionsuofuvariousuorgansuinutheubody.
c. functionaluorustructuraluchangesuresultingufromudiseaseuprocesses.
d. variousucellustructuresuandurelatedufunctions.
ANS:u C
20. Whichuofutheufollowinguisutheubestudefinitionuofuepidemiology?
a. Theuscienceuofutrackingutheuoccurrenceuandudistributionuofudiseases
b. Theurelativeunumberuofudeathsuresultingufromuauparticularudisease
c. Identificationuofuauspecificudiseaseuthroughuevaluationuofusignsuandusymptoms
d. Theuglobalusearchuforuemergingudiseases
ANS:u A
, TestuBankuForuGould'suPathophysiologyuforutheuHealthuProfessionsu7thuEditionuVanMeter 4
21. Whichuofutheufollowingucanucauseucelluinjuryuorudeath?
1. Hypoxia
2. Exposureutouexcessiveucold
3. Excessiveupressureuonuautissue
4. Chemicalutoxins
a. 1,u2
b. 2,u4
c. 1,u3,u4
d. 1,u2,u3,u4
ANS:u D
22. AlluofutheufollowinguareupartuofutheuSevenuStepsutouHealthuEXCEPT:
a. Followucanceruscreeninguguidelines.
b. Useusunublockuagentsuwheneveruexposed.
c. Participateuinustrenuousuexerciseuonuauregularudailyubasis.
d. Chooseuhighufiber,ulowerufatufoods.
ANS:u C
23. Theutermudiseaseurefersuto
a. theuperioduofurecoveryuandureturnutouaunormaluhealthyustate.
b. audeviationufromutheunormalustateuofuhealthuandufunction.
c. theutreatmentumeasuresuusedutoupromoteurecovery.
d. aubasicucollectionuofusignsuandusymptoms.
ANS:u B
24. Aucollectionuofusignsuandusymptoms,uoftenuaffectingumoreuthanuoneuorganuorusystem,uthatuu
suallyuoccurutogetheruinuresponseutouaucertainuconditionuisureferredutouasua(an)
a. acuteudisease.
b. multiorganudisorder.
c. syndrome.
d. manifestation.
ANS:u C
25. AlluofutheufollowingustatementsuareucorrectuaboutucelludamageuEXCEPT:
a. Theuinitialustageuofucelludamageuoftenucausesuanualterationuinumetabolicureactions.
b. Ifutheufactorucausingutheudamageuisuremoveduquickly,utheucellumayubeuableutour
ecoveruandureturnutouitsunormalustate.
c. Ifutheunoxiousufactoruremainsuforuanuextendeduperioduofutime,utheudamageubecomesui
rreversibleuandutheucelludies.
d. Initially,ucelludamageudoesunotuchangeucellumetabolism,ustructure,uorufunction.
ANS:u D
26. Whichuofutheufollowinguconditionsudistinguishesudoubleublindustudiesuuseduinuhealthuresearch?
a. Neitherutheumembersuofutheucontrolugroupuorutheuexperimentalugroupunorutheupersonua
dministeringutheutreatmentuknowsuwhouisureceivingutheuexperimentalutherapy.
b. Bothugroupsuofuresearchusubjectsuandutheupersonuadministeringutheutreatmentuknowuwhoui
sureceivingutheuexperimentalutherapy.
c. Theuresearchusubjectsudounotuknow,ubututheupersonuadministeringutheutreatmentu
knowsuwhouisureceivinguplacebouorustandardutherapy.
d. Onlyumembersuofutheucontrolugroupuknowutheyuareureceivingustandardutherapy.