Lehne's Pharmacology for Nursing Care 10th Edition TEST B
f f f f f f f f
ANK(Chapter 1-110). f
Chapter 3: Drug Regulation, Development, Names, and Information T
f f f f f f f f
est Bank
f
MULTIPLEfCHOICE
1. Afnursefeducatorfisfconductingfafcontinuingfeducationfclassfonfpharmacology.fTofevaluatefthef
learningfoffthefnursesfinfthefclass,fthefnursefeducatorfasks,f―Whichfdrugfnamefisfafgenericfdru
gfname?‖fWhichfisfthefcorrectfresponse?fa.fAcetaminophen
b. Tylenol
c. Cipro
d. Motrin
ANS:fA
Acetaminophenfisfthefgenericfname.fTylenol,fCipro,fandfMotrinfarefallftradefnames.
DIF:fCognitivefLevel:fComprehension REF:fTablef3-
3:fThefThreefTypesfoffDrugfNamesfTOP:fNursingfProcess:fDiagnosis
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fPharmacologicfandfParenteralfTherapies
2. ThefFDAfAmendmentsfActf(FDAAA)fwasfpassedfinf2007ftofaddressfwhichfaspectfoffdrugfsafe
ty?
a. Allowingfpharmaceuticalfcompaniesftofidentifyfoff-
labelfusesfoffmedicationsfapprovedfforfotherfuses
b. Evaluatingfdrugfsafetyfinformationfthatfemergesfafterfafdrugfhasfbeenfapprovedfandfisfinfu
se
c. ExpeditingfthefapprovalfprocessfoffthefU.S.fFoodfandfDrugfAdministrationf(FDA)fsofthat
fneededfdrugsfcanf getftofmarketfmorefquickly
d. Requiringfmanufacturersftofnotifyfpatientsfbeforefremovingfafdrugffromfthefmarket
ANS:fB
ThefFDAAAfwasfpassedftofenablefthefFoodfandfDrugfAdministrationftofcontinuefoversightfoffafdr
ugfafterfgrantingfitfapprovalfsofthatfchangesfinflabelingfcouldfbefmadefasfnecessaryfandfpostmarke
tingfrisksfcouldfbeftrackedfandfidentified.fAfprovisionfoffthefFDAfModernizationfActf(FDAMA),f
passedfinf1997,fallowsfdrugfcompaniesftofpromoteftheirfproductsfforfoff-
labelfusesfasflongfasftheyfpromiseftofconductfstudiesftofsupportftheirfclaims.fRegulationsftofpermitf
acceleratedfapprovalfoffdrugsfforflife-
threateningfdiseasesfwerefadoptedfinf1992fbyfthefFDA.fThefrequirementfthatfdrugfcompaniesfnoti
fyfpatientsf6fmonthsfbeforefremovingfafdrugffromfthefmarketfisfafprovisionfoffthefFDAMA.
DIF:fCognitivefLevel:fComprehension
REF:fLandmarkfDrugfLegislationf
TOP:fNursingfProcess:fEvaluation
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fPharmacologicfandfParenteralfTherapies
,Test Bank Lehne's Pharmacology for Nursing Care, 11th Editio
f f f f f f f f
n by Jacqueline Burchum, Laura Rosenthal Chapter 1-
f f f f f f f
112|Complete Guide A+
f f f
3. Afnursingfstudentfasksfafnursefaboutfpharmaceuticalfresearchfandfwantsftofknowfthefpurposefoffra
ndomizationfinfdrugftrials.fThefnursefexplainsfthatfrandomizationfisfusedfto:
a. ensurefthatfdifferencesfinfoutcomesfarefthefresultfofftreatmentfandfnotfdifferencesfinfsubj
ects.
b. comparefthefoutcomefcausedfbyftheftreatmentftofthefoutcomefcausedfbyfnoftreatment.
,Lehne's Pharmacology for Nursing Care 10th Edition TEST B
f f f f f f f f
ANK(Chapter 1-110). f
c. makefsurefthatfresearchersfarefunawarefoffwhichfsubjectsfarefinfwhichfgroup.
d. preventfsubjectsffromfknowingfwhichfgroupftheyfarefinfandfpreventfpreconceptionfbia
s.
ANS:fA
Randomizationfhelpsfpreventfallocationfbias,fwhichfcanfoccurfwhenfresearchersfplacefsubjectsfwithf
desiredfcharacteristicsfinfthefstudyfgroupfandfotherfsubjectsfinfthefcontrolfgroupfsofthatfdifferencesfi
nfoutcomefarefactuallyfthefresultfoffdifferencesfinfsubjectsfandfnotftreatment.
Comparingftreatmentfoutcomeftofnoftreatmentfoutcomefisfthefdefinitionfoffafcontrolledfstudy.fThef
lastftwofoptionsfdescribefthefusefoffblindingfinfstudies;fblindingfensuresfthatfresearchersforfsubject
sf(orfboth)farefunawarefoffwhichfsubjectsfarefinfwhichfgroupfsofthatfpreconceptionsfaboutfbenefitsf
andfrisksfcannotfbiasfthefresults.
DIF:fCognitivefLevel:fComprehension
REF:fThefRandomizedfDrugfTrialf
TOP:fNursingfProcess:fImplementation
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fPharmacologicfandfParenteralfTherapies
4. Someonefasksfafnursefaboutfafnewfdrugfthatfisfinfpreclinicalftestingfandfwantsftofknowfwhyfitfcann
otfbefusedftoftreatfaffriend‘sfillness.fWhichfstatementfbyfthefnursefisfcorrect?
a. ―Afdrugfatfthisfstagefoffdevelopmentfcanfbefusedfonlyfinfpatientsfwithfseriousfdisease.‖
b. ―Atfthisfstagefoffdrugfdevelopment,fthefsafetyfandfusefulnessfoffthefmedicationfisfunk
nown.‖
c. ―Clinicalftrialsfmustfbefcompletedftofmakefsurefthefdrugfisfsafeftofusefinfhumans.‖
d. ―Untilfpostmarketingfsurveillancefdatafarefavailable,fthefdrugfcannotfbefused.‖
ANS:fB
Preclinicalftestingfmustfbefcompletedfbeforefdrugsfcanfbeftestedfinfhumans.fInfthisfstage,fdrugsfare
fevaluatedfforftoxicities,fpharmacokineticfproperties,fandfpotentiallyfusefulfeffects.fSomefdrugsfc
anfbefusedfinfpatientsfbeforefcompletionfoffPhasefIIIfstudies,fbutfthisfisfafterfpreclinicalftestingfisfc
omplete.fClinicalftrialsfproceedfinfstages,fandfeachfstagefhasfguidelinesfdefiningfhowfafnewfdrugfm
ayfbefusedfandfwhichfpatientsfmayfreceivefit.fPostmarketingfsurveillanceftakesfplacefafterfafdrugfi
sfinfgeneralfuse.
DIF:fCognitivefLevel:fComprehension
REF:fLandmarkfDrugfLegislationf|fStagesfoffDrugfDevelopmentfTOP:f
NursingfProcess:fImplementation
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fReductionfoffRiskfPotential
5. AfpatientfasksfafnursefwhyfdrugsfthatfhavefbeenfapprovedfbyfthefFDAfstillfhavefunknownfsidef
effects.fThefnurseftellfthefpatientfthat:
a. testingfforfallfsidefeffectsfoffafmedicationfwouldfbefprohibitivelyfexpensive.
b. patientsfinfdrugftrialsfoftenfarefbiasedfbyftheirfpreconceptionsfoffafdrug‘sfbenefits.
c. researchersftendftofconductfstudiesfthatfwillfprovefthefbenefitsfofftheirfnewfdrugs.
d. subjectsfinfdrugftrialsfdofnotfalwaysfrepresentftheffullfspectrumfoffpossiblefpatients.
, Test Bank Lehne's Pharmacology for Nursing Care, 11th Editio
f f f f f f f f
n by Jacqueline Burchum, Laura Rosenthal Chapter 1-
f f f f f f f
112|Complete Guide A+ f f f
ANS:fD
Allfdrugftrialsfareflimitedfbyfafrelativelyfsmallfgroupfoffsubjectsfwhofmayfnotfhavefallfthefcharacter
isticsfoffpeoplefwhofwillfbefusingfthefdrug;ftherefore,fsomefsidefeffectsfgofundetectedfuntilfthefdru
gfisfinfuse.fAlthoughfdrugftrialsfarefveryfexpensive,fthisfisfonlyfanfindirectfreasonftheyfdofnotfdetectf
allfsidefeffectsfbeforefapproval.fInftheory,fwell-
designedfdrugftrials,fusingfblindedfstudies,fminimizeforfeliminatefsubjectfbias.fDesigningfstudiesft
ofprovefdesiredfresultsfisfunethical.
DIF:fCognitivefLevel:fAnalysis
REF:fFailureftofDetectfAllfAdversefEffectsfT
OP:fNursingfProcess:fImplementation
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fPharmacologicfandfParenteralfTherapies
6. Afnursefisfteachingfnursingfstudentsfaboutfthefusefoffnonproprietaryfnamesfforfdrugs.fThefnurs
eftellsfthemfwhichffactfaboutfnonproprietaryfnames?
a. TheyfarefapprovedfbyfthefFDAfandfarefeasyftofremember.
b. TheyfarefassignedfbyfthefU.S.fAdoptedfNamesfCouncil.
c. Theyfclearlyfidentifyfthefdrug‘sfpharmacologicalfclassification.
d. Theyfimplyfthefefficacyfoffthefdrugfandfareflessfcomplex.
ANS:fB
Nonproprietary,forfgeneric,fnamesfarefassignedfbyfthefU.S.fAdoptedfNamesfCouncil,fwhichfensur
esfthatfeachfdrugfhasfonlyfonefname.fTradefnames,forfbrandfnames,farefapprovedfbyfthefFDAfandfa
refeasierftofremember.fSomefnonproprietaryfnamesfcontainfsyllablesfthatfidentifyfthefclassificatio
n,falthoughfnotfallfdo.fDrugfnamesfarefnotfsupposedftofidentifyfthefusefforfthefdrug,falthoughfsomef
brandfnamesfdofso.
DIF:fCognitivefLevel:fComprehensionf REF:fDrugfNames:fThefThreefTypesfoffDrugfNamesfTOP:fNursingf
Process:fDiagnosis
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fReductionfoffRiskfPotential
Chapter 1: Orientation to Pharmacology T
f f f f f
est Bank
f
MULTIPLEfCHOICE
1. Thefnursefisfteachingfafpatientfhowfafmedicationfworksftoftreatfanfillness.fTofdofthis,fthefnurs
efwillfrelyfonfknowledgefof:fa.fclinicalfpharmacology.
b. drugfefficacy.
c. pharmacokinetics.
d. pharmacotherapeutics.
ANS:fD
f f f f f f f f
ANK(Chapter 1-110). f
Chapter 3: Drug Regulation, Development, Names, and Information T
f f f f f f f f
est Bank
f
MULTIPLEfCHOICE
1. Afnursefeducatorfisfconductingfafcontinuingfeducationfclassfonfpharmacology.fTofevaluatefthef
learningfoffthefnursesfinfthefclass,fthefnursefeducatorfasks,f―Whichfdrugfnamefisfafgenericfdru
gfname?‖fWhichfisfthefcorrectfresponse?fa.fAcetaminophen
b. Tylenol
c. Cipro
d. Motrin
ANS:fA
Acetaminophenfisfthefgenericfname.fTylenol,fCipro,fandfMotrinfarefallftradefnames.
DIF:fCognitivefLevel:fComprehension REF:fTablef3-
3:fThefThreefTypesfoffDrugfNamesfTOP:fNursingfProcess:fDiagnosis
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fPharmacologicfandfParenteralfTherapies
2. ThefFDAfAmendmentsfActf(FDAAA)fwasfpassedfinf2007ftofaddressfwhichfaspectfoffdrugfsafe
ty?
a. Allowingfpharmaceuticalfcompaniesftofidentifyfoff-
labelfusesfoffmedicationsfapprovedfforfotherfuses
b. Evaluatingfdrugfsafetyfinformationfthatfemergesfafterfafdrugfhasfbeenfapprovedfandfisfinfu
se
c. ExpeditingfthefapprovalfprocessfoffthefU.S.fFoodfandfDrugfAdministrationf(FDA)fsofthat
fneededfdrugsfcanf getftofmarketfmorefquickly
d. Requiringfmanufacturersftofnotifyfpatientsfbeforefremovingfafdrugffromfthefmarket
ANS:fB
ThefFDAAAfwasfpassedftofenablefthefFoodfandfDrugfAdministrationftofcontinuefoversightfoffafdr
ugfafterfgrantingfitfapprovalfsofthatfchangesfinflabelingfcouldfbefmadefasfnecessaryfandfpostmarke
tingfrisksfcouldfbeftrackedfandfidentified.fAfprovisionfoffthefFDAfModernizationfActf(FDAMA),f
passedfinf1997,fallowsfdrugfcompaniesftofpromoteftheirfproductsfforfoff-
labelfusesfasflongfasftheyfpromiseftofconductfstudiesftofsupportftheirfclaims.fRegulationsftofpermitf
acceleratedfapprovalfoffdrugsfforflife-
threateningfdiseasesfwerefadoptedfinf1992fbyfthefFDA.fThefrequirementfthatfdrugfcompaniesfnoti
fyfpatientsf6fmonthsfbeforefremovingfafdrugffromfthefmarketfisfafprovisionfoffthefFDAMA.
DIF:fCognitivefLevel:fComprehension
REF:fLandmarkfDrugfLegislationf
TOP:fNursingfProcess:fEvaluation
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fPharmacologicfandfParenteralfTherapies
,Test Bank Lehne's Pharmacology for Nursing Care, 11th Editio
f f f f f f f f
n by Jacqueline Burchum, Laura Rosenthal Chapter 1-
f f f f f f f
112|Complete Guide A+
f f f
3. Afnursingfstudentfasksfafnursefaboutfpharmaceuticalfresearchfandfwantsftofknowfthefpurposefoffra
ndomizationfinfdrugftrials.fThefnursefexplainsfthatfrandomizationfisfusedfto:
a. ensurefthatfdifferencesfinfoutcomesfarefthefresultfofftreatmentfandfnotfdifferencesfinfsubj
ects.
b. comparefthefoutcomefcausedfbyftheftreatmentftofthefoutcomefcausedfbyfnoftreatment.
,Lehne's Pharmacology for Nursing Care 10th Edition TEST B
f f f f f f f f
ANK(Chapter 1-110). f
c. makefsurefthatfresearchersfarefunawarefoffwhichfsubjectsfarefinfwhichfgroup.
d. preventfsubjectsffromfknowingfwhichfgroupftheyfarefinfandfpreventfpreconceptionfbia
s.
ANS:fA
Randomizationfhelpsfpreventfallocationfbias,fwhichfcanfoccurfwhenfresearchersfplacefsubjectsfwithf
desiredfcharacteristicsfinfthefstudyfgroupfandfotherfsubjectsfinfthefcontrolfgroupfsofthatfdifferencesfi
nfoutcomefarefactuallyfthefresultfoffdifferencesfinfsubjectsfandfnotftreatment.
Comparingftreatmentfoutcomeftofnoftreatmentfoutcomefisfthefdefinitionfoffafcontrolledfstudy.fThef
lastftwofoptionsfdescribefthefusefoffblindingfinfstudies;fblindingfensuresfthatfresearchersforfsubject
sf(orfboth)farefunawarefoffwhichfsubjectsfarefinfwhichfgroupfsofthatfpreconceptionsfaboutfbenefitsf
andfrisksfcannotfbiasfthefresults.
DIF:fCognitivefLevel:fComprehension
REF:fThefRandomizedfDrugfTrialf
TOP:fNursingfProcess:fImplementation
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fPharmacologicfandfParenteralfTherapies
4. Someonefasksfafnursefaboutfafnewfdrugfthatfisfinfpreclinicalftestingfandfwantsftofknowfwhyfitfcann
otfbefusedftoftreatfaffriend‘sfillness.fWhichfstatementfbyfthefnursefisfcorrect?
a. ―Afdrugfatfthisfstagefoffdevelopmentfcanfbefusedfonlyfinfpatientsfwithfseriousfdisease.‖
b. ―Atfthisfstagefoffdrugfdevelopment,fthefsafetyfandfusefulnessfoffthefmedicationfisfunk
nown.‖
c. ―Clinicalftrialsfmustfbefcompletedftofmakefsurefthefdrugfisfsafeftofusefinfhumans.‖
d. ―Untilfpostmarketingfsurveillancefdatafarefavailable,fthefdrugfcannotfbefused.‖
ANS:fB
Preclinicalftestingfmustfbefcompletedfbeforefdrugsfcanfbeftestedfinfhumans.fInfthisfstage,fdrugsfare
fevaluatedfforftoxicities,fpharmacokineticfproperties,fandfpotentiallyfusefulfeffects.fSomefdrugsfc
anfbefusedfinfpatientsfbeforefcompletionfoffPhasefIIIfstudies,fbutfthisfisfafterfpreclinicalftestingfisfc
omplete.fClinicalftrialsfproceedfinfstages,fandfeachfstagefhasfguidelinesfdefiningfhowfafnewfdrugfm
ayfbefusedfandfwhichfpatientsfmayfreceivefit.fPostmarketingfsurveillanceftakesfplacefafterfafdrugfi
sfinfgeneralfuse.
DIF:fCognitivefLevel:fComprehension
REF:fLandmarkfDrugfLegislationf|fStagesfoffDrugfDevelopmentfTOP:f
NursingfProcess:fImplementation
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fReductionfoffRiskfPotential
5. AfpatientfasksfafnursefwhyfdrugsfthatfhavefbeenfapprovedfbyfthefFDAfstillfhavefunknownfsidef
effects.fThefnurseftellfthefpatientfthat:
a. testingfforfallfsidefeffectsfoffafmedicationfwouldfbefprohibitivelyfexpensive.
b. patientsfinfdrugftrialsfoftenfarefbiasedfbyftheirfpreconceptionsfoffafdrug‘sfbenefits.
c. researchersftendftofconductfstudiesfthatfwillfprovefthefbenefitsfofftheirfnewfdrugs.
d. subjectsfinfdrugftrialsfdofnotfalwaysfrepresentftheffullfspectrumfoffpossiblefpatients.
, Test Bank Lehne's Pharmacology for Nursing Care, 11th Editio
f f f f f f f f
n by Jacqueline Burchum, Laura Rosenthal Chapter 1-
f f f f f f f
112|Complete Guide A+ f f f
ANS:fD
Allfdrugftrialsfareflimitedfbyfafrelativelyfsmallfgroupfoffsubjectsfwhofmayfnotfhavefallfthefcharacter
isticsfoffpeoplefwhofwillfbefusingfthefdrug;ftherefore,fsomefsidefeffectsfgofundetectedfuntilfthefdru
gfisfinfuse.fAlthoughfdrugftrialsfarefveryfexpensive,fthisfisfonlyfanfindirectfreasonftheyfdofnotfdetectf
allfsidefeffectsfbeforefapproval.fInftheory,fwell-
designedfdrugftrials,fusingfblindedfstudies,fminimizeforfeliminatefsubjectfbias.fDesigningfstudiesft
ofprovefdesiredfresultsfisfunethical.
DIF:fCognitivefLevel:fAnalysis
REF:fFailureftofDetectfAllfAdversefEffectsfT
OP:fNursingfProcess:fImplementation
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fPharmacologicfandfParenteralfTherapies
6. Afnursefisfteachingfnursingfstudentsfaboutfthefusefoffnonproprietaryfnamesfforfdrugs.fThefnurs
eftellsfthemfwhichffactfaboutfnonproprietaryfnames?
a. TheyfarefapprovedfbyfthefFDAfandfarefeasyftofremember.
b. TheyfarefassignedfbyfthefU.S.fAdoptedfNamesfCouncil.
c. Theyfclearlyfidentifyfthefdrug‘sfpharmacologicalfclassification.
d. Theyfimplyfthefefficacyfoffthefdrugfandfareflessfcomplex.
ANS:fB
Nonproprietary,forfgeneric,fnamesfarefassignedfbyfthefU.S.fAdoptedfNamesfCouncil,fwhichfensur
esfthatfeachfdrugfhasfonlyfonefname.fTradefnames,forfbrandfnames,farefapprovedfbyfthefFDAfandfa
refeasierftofremember.fSomefnonproprietaryfnamesfcontainfsyllablesfthatfidentifyfthefclassificatio
n,falthoughfnotfallfdo.fDrugfnamesfarefnotfsupposedftofidentifyfthefusefforfthefdrug,falthoughfsomef
brandfnamesfdofso.
DIF:fCognitivefLevel:fComprehensionf REF:fDrugfNames:fThefThreefTypesfoffDrugfNamesfTOP:fNursingf
Process:fDiagnosis
MSC:fNCLEXfClientfNeedsfCategory:fPhysiologicfIntegrity:fReductionfoffRiskfPotential
Chapter 1: Orientation to Pharmacology T
f f f f f
est Bank
f
MULTIPLEfCHOICE
1. Thefnursefisfteachingfafpatientfhowfafmedicationfworksftoftreatfanfillness.fTofdofthis,fthefnurs
efwillfrelyfonfknowledgefof:fa.fclinicalfpharmacology.
b. drugfefficacy.
c. pharmacokinetics.
d. pharmacotherapeutics.
ANS:fD
