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NURG 533 Patho Module 4: Cancer and Hematology

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NURG 533 Patho Module 4: Cancer and Hematology

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NURG 533 Patho Module 4: Cancer and Hematology



1. What are the eight hallmarks of cancer?: Uncontrolled cellular proliferation/ sustained proliferative signaling
evading growth suppression genomic
instability replicative immortality
inducing angiogenesis and reprogramming energy metabolism apoptotic cell death
promoting tumor inflammation and avoiding immune destruction activating invasion and metastasis.

2. What are the three most common childhood cancers?: Leukemias, sarcomas, and embryonic tumors
3. When are childhood cancers most often diagnosed?: Most often between the ages of 2 and 5, during times of rapid
growth.

4. What is the most common malignancy in children?: leukemia
5. These are early-stage cancers found in the _epithelial tumors of glandular or squamous cell origin in a
number of sites.: Carcinoma in situ

6. Preinvasive epithelial malignant tumors of glandular or epithelial origin that have not broken through the
basement membrane or invaded the surrounding stroma: carcinoma in situ

7. These tumors grow slowly, have a well-defined capsule, not invasive, well differentiated, have a low mitotic
index, and do not metastasize.: Benign tumors

8. These tumors grow rapidly, are not encapsulated, are invasive, poorly dif- ferentiated, have a high mitotic
index, and can metastasize.: Malignant tumors

9. True or False. Benign tumors are named according to the tissues from which they arise and include the suffix "-
oma": true

10.benign fatty tumors: lipoma
11.benign tumors from nerve cells (brain and spine): glioma
12.benign tumors from the smooth muscle: leiomyoma
13.benign tumors from cartilage: chondroma
14.Malignant epithelial tumors: carcinomas
15.malignant connective tissue tumors: sarcomas
16.what are some examples of carcinomas?: Basal cell and squamous cell

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, NURG 533 Patho Module 4: Cancer and Hematology
17.what are some examples of sarcomas?: chondrosarcoma and osteosarcoma
18.cancers of lymphatic tissues: lymphomas
19.cancers of blood-forming cells: leukemias
20.What is the most important and deadly characteristic of a malignant tumor, is a defining characteristic of
cancer, significantly contributes to pain and suffering associated with cancer, and is a major cause of death from
cancer?-
: metastasis




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