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McCance & Huether’s Pathophysiology The Biologic Basis for Disease in Adults and Chi
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ldren 9th Edition by Julia Rogers
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Chapter 1-49 C
Chapter 01: Cellular Biology
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Rogers: McCance & Huether’s Pathophysiology, 9th Edition
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MULTIPLECCHOICE
1. WhichCstatementCbestCdescribesCtheCcellularCfunctionCofCmetabolicCabsorption?
a. CellsCcanCproduceCproteins.
b. CellsCcanCsecreteCdigestiveCenzymes.
c. CellsCcanCtakeCinCandCuseCnutrients.
d. CellsCcanCsynthesizeCfats.
ANS:C C
InCmetabolicCabsorption,CallCcellsCtakeCinCandCuseCnutrientsCandCotherCsubstancesCfromCthei
rCsurroundings.CTheCremainingCoptionsCareCnotCinclusiveCinCtheirCdescriptionsCofCcellularC
metabolicCabsorption.
DIF: CognitiveCLevel:CRemembering
2. WhereCisCmostCofCaCcell’sCgeneticCinformation,CincludingCRNACandCDNA,Ccontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:C C
TheCnucleusCcontainsCtheCnucleolus,CaCsmallCdenseCstructureCcomposedClargelyCofCRNA,Cmo
stCofCtheCcellularCDNA,CandCtheCDNA-
bindingCproteins,CsuchCasCtheChistones,CwhichCregulateCitsCactivity.CTheCmitochondriaCareCres
ponsibleCforCcellularCrespirationCandCenergyCproduction.
Ribosomes’CchiefCfunctionCisCtoCprovideCsitesCforCcellularCproteinCsynthesis.CLysosome
sCfunctionCasCtheCintracellularCdigestiveCsystem.
DIF: CognitiveCLevel:CRemembering
3. WhichCcomponentCofCtheCcellCproducesChydrogenCperoxideC(H2O2)CbyCusingCoxygenCtoCremov
eChydrogenCatomsCfromCspecificCsubstratesCinCanCoxidativeCreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
ANS:C B
,d. Endosome
ANS:C B
, PeroxisomesCareCsoCnamedCbecauseCtheyCusuallyCcontainCenzymesCthatCuseCoxygenCtoCremoveC
hydrogenCatomsCfromCspecificCsubstratesCinCanCoxidativeCreactionCthatCproducesCH2O2,CwhichCi
sCaCpowerfulCoxidantCandCpotentiallyCdestructiveCifCitCaccumulatesCorCescapesCfromCperoxisome
s.CRibosomesCareCRNA-
proteinCcomplexesC(nucleoproteins)CthatCareCsynthesizedCinCtheCnucleolusCandCsecretedCintoCthe
CcytoplasmCthroughCpores CinCtheCnuclearCenvelopeCcalledCnuclearCporeCcomplexes.CLysosomes
CareCsaclikeCstructuresCthatCoriginateCfromCtheCGolgiCcomplexCandCcontainCmoreCthanC40Cdigest
iveCenzymesCcalledChydrolases,CwhichCcatalyzeCbondsCinCproteins,Clipids,CnucleicCacids,CandCca
rbohydrates.CAnCendosomeCisCaCvesicalCthatChasCbeenCpinchedCoffCfromCtheCcellularCmembrane.
DIF: CognitiveCLevel:CRemembering
4. WhichCcellCcomponentCisCcapableCofCcellularCautodigestionCwhenCitCisCreleasedCduringCce
llCinjury?
a. Ribosome
b. GolgiCcomplex
c. SmoothCendoplasmicCreticulum
d. Lysosomes
ANS:C D
TheClysosomalCmembraneCactsCasCaCprotectiveCshieldCbetweenCtheCpowerfulCdigestiveCenzyme
sCwithinCtheClysosomeCandCtheCcytoplasm,CpreventingCtheirCleakageCintoCtheCcytoplasmicCmatri
x.CDisruptionCofCtheCmembraneCbyCvariousCtreatmentsCorCcellularCinjuryCleadsCtoCaCreleaseCofCt
heClysosomalCenzymes,CwhichCcanCthenCreactCwithCtheirCspecificCsubstrates,CcausingCcellularCs
elf-
digestion.CTheCchiefCfunctionCofCaCribosomeCisCtoCprovideCsitesCforCcellularCproteinCsynthesis.C
C
TheCGolgiCcomplexCisCaCnetworkCofCflattened,CsmoothCvesiclesCandCmembranesCoftenClocatedC
nearCtheCcellCnucleus.CTheCsmoothCendoplasmicCreticulumCisCinvolvedCinCsteroidChormoneCpro
ductionCandCremovingCtoxicCsubstancesCfromCtheCcell.
DIF: CognitiveCLevel:CRemembering
5. WhichCcAMP-mediatedCresponseCisCrelatedCtoCantidiureticChormone?
a. IncreasedCheartCrateCandCforceCofCcontraction
b. SecretionCofCcortisol
c. IncreasedCretentionCofCwater
d. BreakdownCofCfat
ANS:C C
AntidiureticChormoneCleadsCtoCincreasedCretentionCofCwaterCinCtheCbody.CEpinephrineCcauses
CincreasesCinCheartCrateCandCforceCofCcontraction.CIncreasedCcortisolCsecretionCisCdueCtoCACT
H.CBreakdownCofCfatCisCdueCtoCglucagon.
DIF: CognitiveCLevel:CRemembering
6. DuringCwhichCphaseCofCtheCcellCcycleCisCDNACsynthesized?
a. G1
b. S
c. G2
ANS:C B
, d. M
ANS:C B