DHG-213; Final Exam Review
1. Studies the effects of the drug on the body: pharmacodynamics
2. Studies the process of the distribution of the drugs in the body, their absorption, excretion and
metabolism: pharmacokinetics
3. The drug can activate a receptor to elicit a response: agonist
4. The drug does not activate a receptor therefore the response is reduced or blocked: antagonist
5. Effective dose for 50% of subjects or the dose that produces half of the maximum effect: ED50
6. Ratio between LD50 and ED50: therapeutic index (safety margin)
7. The duration of action of a drug: half life
8. A pharmacological phenomenon in which a medication undergoes metab- olism at a specific location in the
body: first pass effect
9. Carry messages between nerves; assist in message crossing the synapse-
: neurotransmitters
10.Regulates involuntary bodily functions: autonomic nervous system
11.Fight or flight response
- Lumbar and thoracic portion of spinal cord
- Targets muscles and glands
- Diffuse effect on the body: sympathetic (SANS)
12.Rest and digest response
- Secretions are increased
- Spinal cord and cranial nerves
- Targets organs to slow down: parasympathetic
13.Primary neurotransmitter for PANS: acetylcholine
14.Primary neurotransmitters for SANS: norepinephrine and epinephrine
15.AKA cholinergic system: PANS
16.Drugs that imitate acetylcholine: parasympathomimetic (cholinergic drugs)
17.Drugs that block or inhibit acetycholine: parasympatholytic (anticholinergic drugs)
18.Which PANS receptor?
- Synapse between postganglionic and the effector tissues: muscarinic
19.Which PANS receptor?
- Synapse between preganglionic and postganglionic nerves: nicotinic
20.A neurotransmitter clustered in the midbrain in an area called the substan- tia nigra: dopamine
21.AKA adrenergic system: SANS
22.Drugs that imitate epinephrine: sympathomimetic (adrenergic drugs)
23.Drugs that block or inhibit epinephrine: sympatholytic (antiadrenergic drugs)
, DHG-213; Final Exam Review
24.Which receptor tends to excite: alpha
1. Studies the effects of the drug on the body: pharmacodynamics
2. Studies the process of the distribution of the drugs in the body, their absorption, excretion and
metabolism: pharmacokinetics
3. The drug can activate a receptor to elicit a response: agonist
4. The drug does not activate a receptor therefore the response is reduced or blocked: antagonist
5. Effective dose for 50% of subjects or the dose that produces half of the maximum effect: ED50
6. Ratio between LD50 and ED50: therapeutic index (safety margin)
7. The duration of action of a drug: half life
8. A pharmacological phenomenon in which a medication undergoes metab- olism at a specific location in the
body: first pass effect
9. Carry messages between nerves; assist in message crossing the synapse-
: neurotransmitters
10.Regulates involuntary bodily functions: autonomic nervous system
11.Fight or flight response
- Lumbar and thoracic portion of spinal cord
- Targets muscles and glands
- Diffuse effect on the body: sympathetic (SANS)
12.Rest and digest response
- Secretions are increased
- Spinal cord and cranial nerves
- Targets organs to slow down: parasympathetic
13.Primary neurotransmitter for PANS: acetylcholine
14.Primary neurotransmitters for SANS: norepinephrine and epinephrine
15.AKA cholinergic system: PANS
16.Drugs that imitate acetylcholine: parasympathomimetic (cholinergic drugs)
17.Drugs that block or inhibit acetycholine: parasympatholytic (anticholinergic drugs)
18.Which PANS receptor?
- Synapse between postganglionic and the effector tissues: muscarinic
19.Which PANS receptor?
- Synapse between preganglionic and postganglionic nerves: nicotinic
20.A neurotransmitter clustered in the midbrain in an area called the substan- tia nigra: dopamine
21.AKA adrenergic system: SANS
22.Drugs that imitate epinephrine: sympathomimetic (adrenergic drugs)
23.Drugs that block or inhibit epinephrine: sympatholytic (antiadrenergic drugs)
, DHG-213; Final Exam Review
24.Which receptor tends to excite: alpha