2025 NGN HESI RN PHARMACOLOGY REAL EXAMS (4 VERSIONS) WITH
ALL QUESTIONS AND CORRECT ANSWERS WITH RATIONALES (100%
CORRECT ANSWERS) RN HESI PHARMACOLOGY WITH NGN LATEST 4
VERSIONS 2024/2025
Question 1: Multiple Choice
A nurse is reviewing the medication list of a client who is starting lithium therapy
for bipolar disorder. Which of the following medications should the nurse identify
as contraindicated with lithium?
A. Furosemide
B. Aspirin
C. Acetaminophen
D. Propranolol
Answer: A. Furosemide
Rationale: Furosemide, a loop diuretic, can increase the risk of lithium toxicity due
to sodium depletion. Lithium and sodium levels are closely linked, so diuretics can
disrupt this balance.
Question 2: True/False
It is safe to administer tetracycline to a pregnant client.
Answer: False
Rationale: Tetracycline is contraindicated in pregnancy because it can cause
permanent discoloration of teeth and affect bone development in the fetus.
Question 3: Fill-in-the-Blank
When administering warfarin, the nurse should monitor the client’s __________
levels to determine therapeutic effect.
,Answer: INR (International Normalized Ratio)
Rationale: Warfarin therapy is monitored using the INR, with a therapeutic range
typically between 2-3 for most conditions.
Question 4: Scenario-Based Multiple Choice
A client taking digoxin reports nausea, blurred vision, and seeing yellow halos
around lights. The nurse should check which of the following lab values
immediately?
A. Blood glucose
B. Potassium
C. Digoxin level
D. Sodium
Answer: C. Digoxin level
Rationale: These symptoms indicate digoxin toxicity. Digoxin levels must be
monitored to ensure they are within the therapeutic range (0.5-2 ng/mL).
Question 5: Multiple Response
Which of the following should a nurse include in the teaching for a client
prescribed albuterol inhaler? (Select all that apply.)
A. "Use the inhaler 15 minutes before exercise."
B. "This medication is for long-term control of asthma."
C. "Wait at least 1 minute between puffs."
D. "Rinse your mouth after using this inhaler."
E. "Shake the inhaler well before use."
Answers: A, C, E
Rationale: Albuterol is a short-acting beta-agonist used for quick relief and
prevention of exercise-induced bronchospasm. Proper inhaler technique includes
waiting between puffs and shaking the inhaler. Rinsing is not required for
albuterol (it's more critical for corticosteroid inhalers).
, Question 6: Matching
Match the medication to its side effect:
1. ACE inhibitors
2. Opioids
3. Loop diuretics
4. SSRIs
A. Cough
B. Serotonin syndrome
C. Hypokalemia
D. Constipation
Answers:
1 - A. Cough
2 - D. Constipation
3 - C. Hypokalemia
4 - B. Serotonin syndrome
Rationale: These are common side effects associated with these classes of
medications.
Question 7: Multiple Choice
A nurse is administering heparin subcutaneously to a client. Which of the
following actions should the nurse take?
A. Aspirate for blood return before injecting.
B. Rub the injection site after administering.
C. Use a 22-gauge needle for injection.
D. Inject the medication into the abdomen.
Answer: D. Inject the medication into the abdomen.
Rationale: Heparin is commonly administered subcutaneously in the abdomen.
The nurse should not aspirate or rub the site to avoid hematoma formation.
ALL QUESTIONS AND CORRECT ANSWERS WITH RATIONALES (100%
CORRECT ANSWERS) RN HESI PHARMACOLOGY WITH NGN LATEST 4
VERSIONS 2024/2025
Question 1: Multiple Choice
A nurse is reviewing the medication list of a client who is starting lithium therapy
for bipolar disorder. Which of the following medications should the nurse identify
as contraindicated with lithium?
A. Furosemide
B. Aspirin
C. Acetaminophen
D. Propranolol
Answer: A. Furosemide
Rationale: Furosemide, a loop diuretic, can increase the risk of lithium toxicity due
to sodium depletion. Lithium and sodium levels are closely linked, so diuretics can
disrupt this balance.
Question 2: True/False
It is safe to administer tetracycline to a pregnant client.
Answer: False
Rationale: Tetracycline is contraindicated in pregnancy because it can cause
permanent discoloration of teeth and affect bone development in the fetus.
Question 3: Fill-in-the-Blank
When administering warfarin, the nurse should monitor the client’s __________
levels to determine therapeutic effect.
,Answer: INR (International Normalized Ratio)
Rationale: Warfarin therapy is monitored using the INR, with a therapeutic range
typically between 2-3 for most conditions.
Question 4: Scenario-Based Multiple Choice
A client taking digoxin reports nausea, blurred vision, and seeing yellow halos
around lights. The nurse should check which of the following lab values
immediately?
A. Blood glucose
B. Potassium
C. Digoxin level
D. Sodium
Answer: C. Digoxin level
Rationale: These symptoms indicate digoxin toxicity. Digoxin levels must be
monitored to ensure they are within the therapeutic range (0.5-2 ng/mL).
Question 5: Multiple Response
Which of the following should a nurse include in the teaching for a client
prescribed albuterol inhaler? (Select all that apply.)
A. "Use the inhaler 15 minutes before exercise."
B. "This medication is for long-term control of asthma."
C. "Wait at least 1 minute between puffs."
D. "Rinse your mouth after using this inhaler."
E. "Shake the inhaler well before use."
Answers: A, C, E
Rationale: Albuterol is a short-acting beta-agonist used for quick relief and
prevention of exercise-induced bronchospasm. Proper inhaler technique includes
waiting between puffs and shaking the inhaler. Rinsing is not required for
albuterol (it's more critical for corticosteroid inhalers).
, Question 6: Matching
Match the medication to its side effect:
1. ACE inhibitors
2. Opioids
3. Loop diuretics
4. SSRIs
A. Cough
B. Serotonin syndrome
C. Hypokalemia
D. Constipation
Answers:
1 - A. Cough
2 - D. Constipation
3 - C. Hypokalemia
4 - B. Serotonin syndrome
Rationale: These are common side effects associated with these classes of
medications.
Question 7: Multiple Choice
A nurse is administering heparin subcutaneously to a client. Which of the
following actions should the nurse take?
A. Aspirate for blood return before injecting.
B. Rub the injection site after administering.
C. Use a 22-gauge needle for injection.
D. Inject the medication into the abdomen.
Answer: D. Inject the medication into the abdomen.
Rationale: Heparin is commonly administered subcutaneously in the abdomen.
The nurse should not aspirate or rub the site to avoid hematoma formation.
