Test Bank For Clayton’s Basic Pharmacology for Nurses 19th EditionB
d d d d d d d d d d
y Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Complet
d d d d d d d d d
e
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz
d d d d d d d d
: Clayton’s Basic Pharmacology for Nurses, 19th Edition
d d d d d d d
MULTIPLEdCHOICE
1. WhichdnamedidentifiesdaddrugdlisteddbydthedUSdFooddandd
DrugdAdministrationd(FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS:d C
Thedofficialdnamedisdthed namedunderdwhichdaddrugdisdlisteddby
dthedFDA.dThedbranddname,dordtrademark,disdthednamedgivendt
odaddrugdbyditsdmanufacturer.dThednonproprietary,dordgeneric,d
namedisdprovideddbydthedUniteddStatesdAdopteddNamesdCoun
cil.
DIF: CognitivedLevel:dKnowledge REF:d p.d9
OBJ:d1NAT:dNCLEXdClientdNeedsdCategory:dSafe,dEffectivedCared
EnvironmentdTOP:d NursingdProcessdStep:dAssessment
CON:d
PatientdEducation
2. Whichdsourcedcontainsdinformationdspecificdtodnutritionaldsupplements?
a. USPdDictionarydofdUSANd &dInternationaldDrugdNames
b. NaturaldMedicinesdComprehensivedDatabase
c. UniteddStatesdPharmacopoeia/NationaldFormularyd(USPdNF)
d. DrugdInteractiondFacts
ANS:d C
UniteddStatesdPharmacopoeia/NationaldFormularydcontainsdinformationdspecificdtodnutritionalds
upplements.dUSPdDictionarydofdUSANd&dInternationaldDrugdNamesdisdadcompilationdofddrugdna
mes,dpronunciationdguide,danddpossibledfuturedFDAdapprovedddrugs;ditddoesdnotdincludednutritio
naldsupplements.dNaturaldMedicinesdComprehensivedDatabasedcontains
evidence-
baseddinformationdondherbaldmedicinesdanddherbaldcombinationdproducts;ditddoesdnotdincludedinf
ormationdspecificdtodnutritionaldsupplements.dDrugdInteractiondFactsdcontainsdcomprehensivedi
nformationdonddrugdinteractiondfacts;ditddoesdnotdincludednutritionaldsupplements.
DIF: CognitivedLevel:dKnowledge REF:d p.d4
OBJ:d3dNAT:d NCLEXdClientdNeedsdCategory:dPhysiologicaldIntegr
ity
TOP:d NursingdProcessdStep:dAssessment CON:d Nutritiond|dPatientdEducation
3. Whichddrugdreferencedcontainsddrugdmonographsdthatddescribedallddrugsdindadtherapeuticdclass?
a. DrugdFactsdanddComparisons
,TestdBankdFordClayton’sdBasicdPharmacologydfordNursesd19thdEdition 3
b. DrugdInteractiondFacts
c. HandbookdondInjectabledDrugs
d. Martindale—ThedCompletedDrugdReference
ANS:d A
DrugdFactsdanddComparisonsdcontainsddrugdmonographsdthatddescribedallddrugsdindadth
erapeuticdclass.dMonographsdaredformatteddasdtablesdtodallowdcomparisondofdsimilardprod
ucts,dbranddnames,dmanufacturers,dcostdindices,danddavailableddosagedformsdOnlinedver
siondisdavailable.
DIF: CognitivedLevel:dKnowledge REF:d p.d4dTabled1.2
OBJ:ddd 3 NAT:d NCLEXdClientdNeedsdCategory:dPhysiologicaldIntegrity
TOP:d NursingdProcessdStep:dAssessment CON:d Safetyd|dPatientdEducationd|dClinicaldJudgment
4. Whichddrugdreferencedcontainsd monographsdaboutd virtuallydeverydsingle-
entityddrugdavailabledindthedUniteddStatesdandddescribesdtherapeuticdusesdofddrugs,dincludingdap
proveddanddunapprovedduses?
a. Martindale:dThedCompletedDrugdReference
b. AHFSdDrugdInformation
c. DrugdReference
d. DrugdFactsdanddComparisons
ANS:d B
AHFSdDrugdInformationdcontainsdmonographsdaboutdvirtuallydeverydsingle-
entityddrugdavailabledindthedUniteddStatesdandddescribesdtherapeuticdusesdofddrugs,dincludingdappr
oveddanddunapprovedduses.
DIF: CognitivedLevel:dKnowledge REF:d p.d4dTabled1.2
OBJ:ddd 3 NAT:d NCLEXdClientdNeedsdCategory:dPhysiologicaldIntegrity
TOP:d NursingdProcessdStep:dPlanning CON:d Safetyd|dPatientdEducationd|dClinicaldJudgment
5. Whichdonlineddrugdreferencedmakesdavailabledtodhealthcaredprovidersdanddthedpublicdadstand
ard,dcomprehensive,dup-to-datedlookdupdandddownloadabledresourcedaboutdmedicines?
a. AmericandDrugdIndex
b. AmericandHospitaldFormulary
c. DailyMed
d. DrugdReference
ANS:d C
DailyMeddmakesdavailabledtodhealthcaredprovidersdanddthedpublicdadstandard,dcomprehensive,du
p-to-
datedlookdupdandddownloadabledresourcedaboutdmedicines.dThedAmericandDrugdIndexdisdnotdapp
ropriatedfordpatientduse.dThedAmericandHospitaldFormularydisdnotdappropriatedfordpatientduse.d
Theddrugdreferencedisdnotdappropriatedfordpatientd use.
DIF: CognitivedLevel:dKnowledge REF:d p.d3d|dp.d4
OBJ:d3dNAT:d NCLEXdClientdNeedsdCategory:dPhysiologicaldIntegr
ity
TOP:d NursingdProcessdStep:dImplementation
CON:d Safetyd|dPatientdEducationd|dClinicaldJudgment
6. WhichdlegislationdauthorizesdthedFDAdtoddeterminedthedsafetydofdaddrugdbeforeditsdmarketing?
a. FederaldFood,dDrug,danddCosmeticdActd(1938)
b. DurhamdHumphreydAmendmentd(1952)
, TestdBankdFordClayton’sdBasicdPharmacologydfordNursesd19thdEdition 4
c. ControlleddSubstancesdActd(1970)
d. KefauverdHarrisdDrugdAmendmentd(1962)
ANS:d A
ThedFederaldFood,dDrug,danddCosmeticdActdofd1938dauthorizeddthedFDAdtoddeterminedthedsafet
ydofdallddrugsdbeforedmarketing.dLaterdamendmentsdanddactsdhelpeddtightendFDAdcontroldandden
sureddrugdsafety.dThedDurhamdHumphreydAmendmentddefinesdthedkindsdofddrugsdthatdcannotdb
eduseddsafelydwithoutdmedicaldsupervisiondanddrestrictsdtheirdsaledtodprescriptiondbydadlicenseddp
ractitioner.dThedControlleddSubstancesdActdaddressesdonlydcontrolleddsubstancesdanddtheirdcateg
orization.dThedKefauverdHarrisdDrugdAmendmentdensuresddrugdefficacydanddgreaterddrugdsafety.
dDrugdmanufacturersdaredrequireddtodprovedtodthedFDAdthedeffectivenessdofdtheirdproductsdbefor
edmarketingdthem.
DIF: CognitivedLevel:dKnowledge REF:dp.d 5dTabledl.3
OBJ:d 5
NAT:dNCLEXdClientdNeedsdCategory:dPhysiologicaldIntegrityd
TOP:d NursingdProcessdStep:dAssessment
CON:d Safetyd|dPatientdEducationd|dEvidenced|dHealthdCaredLaw
7. Whichdclassificationddoesdmeperidined(Demerol)dfalldunder?
a. I
b. II
c. III
d. IV
ANS:d B
Meperidined(Demerol)disdadScheduledIIddrug;ditdhasdadhighdpotentialdfordabusedanddmaydleaddtodse
veredpsychologicaldanddphysicalddependence.dScheduledIddrugsdhavedhighdpotentialdfordabusedand
dnodrecognizeddmedicalduse.dScheduledIIIddrugsdhavedsomedpotentialdfordabuse.dUsedmaydleaddto
dlowdtodmoderatedphysicalddependencedordhighdpsychologicalddependence.dScheduledIVddrugsdh
avedlowdpotentialdfordabuse.dUsedmaydleaddtodlimiteddphysicaldordpsychologicalddependence.
DIF: CognitivedLevel:dKnowledge REF:d p.d10
OBJ:d2dNAT:d NCLEXdClientdNeedsdCategory:dSafe,dEffectivedCared
Environment
TOP:d NursingdProcessdStep:dAssessment CON:d PatientdEducationd|dAddictiond|dPain
8. WhichdactiondwoulddthedFDAdtakedtodexpediteddrugddevelopmentd anddapprovaldfordandoutbreakdo
fdsmallpox?
a. Listdsmallpoxdasdadhealthdorphanddisease.
b. Omitdthedpreclinicaldresearchdphase.
c. Extenddthedclinicaldresearchdphase.
d. Fastdtrackdthedinvestigationalddrug.
ANS:d D
OncedthedInvestigationaldNewdDrugdApplicationdhasdbeendapproved,dtheddrugdcandreceivedhighe
stdprioritydwithindthedagency,dwhichdisdcalleddfastdtracking.dAdsmallpoxdoutbreakdwoulddbecome
dadprioritydconcerndindthedworld.dOrphanddiseasesdarednotdresearcheddindadprioritydmanner.dPrecli
nicaldresearchdisdnotdomitted.dExtendingdanydphasedofdthedresearchdwoulddmeandadlongerdtimedtod
developdadvaccine.dThedFDAdmustdensuredthatdalldphasesdofdthedpreclinicaldanddclinicaldresearchdp
hasedhavedbeendcompleteddindadsafedmanner.
DIF: CognitivedLevel:dKnowledge REF:dddp.d7 OBJ:d 5
d d d d d d d d d d
y Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Complet
d d d d d d d d d
e
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz
d d d d d d d d
: Clayton’s Basic Pharmacology for Nurses, 19th Edition
d d d d d d d
MULTIPLEdCHOICE
1. WhichdnamedidentifiesdaddrugdlisteddbydthedUSdFooddandd
DrugdAdministrationd(FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS:d C
Thedofficialdnamedisdthed namedunderdwhichdaddrugdisdlisteddby
dthedFDA.dThedbranddname,dordtrademark,disdthednamedgivendt
odaddrugdbyditsdmanufacturer.dThednonproprietary,dordgeneric,d
namedisdprovideddbydthedUniteddStatesdAdopteddNamesdCoun
cil.
DIF: CognitivedLevel:dKnowledge REF:d p.d9
OBJ:d1NAT:dNCLEXdClientdNeedsdCategory:dSafe,dEffectivedCared
EnvironmentdTOP:d NursingdProcessdStep:dAssessment
CON:d
PatientdEducation
2. Whichdsourcedcontainsdinformationdspecificdtodnutritionaldsupplements?
a. USPdDictionarydofdUSANd &dInternationaldDrugdNames
b. NaturaldMedicinesdComprehensivedDatabase
c. UniteddStatesdPharmacopoeia/NationaldFormularyd(USPdNF)
d. DrugdInteractiondFacts
ANS:d C
UniteddStatesdPharmacopoeia/NationaldFormularydcontainsdinformationdspecificdtodnutritionalds
upplements.dUSPdDictionarydofdUSANd&dInternationaldDrugdNamesdisdadcompilationdofddrugdna
mes,dpronunciationdguide,danddpossibledfuturedFDAdapprovedddrugs;ditddoesdnotdincludednutritio
naldsupplements.dNaturaldMedicinesdComprehensivedDatabasedcontains
evidence-
baseddinformationdondherbaldmedicinesdanddherbaldcombinationdproducts;ditddoesdnotdincludedinf
ormationdspecificdtodnutritionaldsupplements.dDrugdInteractiondFactsdcontainsdcomprehensivedi
nformationdonddrugdinteractiondfacts;ditddoesdnotdincludednutritionaldsupplements.
DIF: CognitivedLevel:dKnowledge REF:d p.d4
OBJ:d3dNAT:d NCLEXdClientdNeedsdCategory:dPhysiologicaldIntegr
ity
TOP:d NursingdProcessdStep:dAssessment CON:d Nutritiond|dPatientdEducation
3. Whichddrugdreferencedcontainsddrugdmonographsdthatddescribedallddrugsdindadtherapeuticdclass?
a. DrugdFactsdanddComparisons
,TestdBankdFordClayton’sdBasicdPharmacologydfordNursesd19thdEdition 3
b. DrugdInteractiondFacts
c. HandbookdondInjectabledDrugs
d. Martindale—ThedCompletedDrugdReference
ANS:d A
DrugdFactsdanddComparisonsdcontainsddrugdmonographsdthatddescribedallddrugsdindadth
erapeuticdclass.dMonographsdaredformatteddasdtablesdtodallowdcomparisondofdsimilardprod
ucts,dbranddnames,dmanufacturers,dcostdindices,danddavailableddosagedformsdOnlinedver
siondisdavailable.
DIF: CognitivedLevel:dKnowledge REF:d p.d4dTabled1.2
OBJ:ddd 3 NAT:d NCLEXdClientdNeedsdCategory:dPhysiologicaldIntegrity
TOP:d NursingdProcessdStep:dAssessment CON:d Safetyd|dPatientdEducationd|dClinicaldJudgment
4. Whichddrugdreferencedcontainsd monographsdaboutd virtuallydeverydsingle-
entityddrugdavailabledindthedUniteddStatesdandddescribesdtherapeuticdusesdofddrugs,dincludingdap
proveddanddunapprovedduses?
a. Martindale:dThedCompletedDrugdReference
b. AHFSdDrugdInformation
c. DrugdReference
d. DrugdFactsdanddComparisons
ANS:d B
AHFSdDrugdInformationdcontainsdmonographsdaboutdvirtuallydeverydsingle-
entityddrugdavailabledindthedUniteddStatesdandddescribesdtherapeuticdusesdofddrugs,dincludingdappr
oveddanddunapprovedduses.
DIF: CognitivedLevel:dKnowledge REF:d p.d4dTabled1.2
OBJ:ddd 3 NAT:d NCLEXdClientdNeedsdCategory:dPhysiologicaldIntegrity
TOP:d NursingdProcessdStep:dPlanning CON:d Safetyd|dPatientdEducationd|dClinicaldJudgment
5. Whichdonlineddrugdreferencedmakesdavailabledtodhealthcaredprovidersdanddthedpublicdadstand
ard,dcomprehensive,dup-to-datedlookdupdandddownloadabledresourcedaboutdmedicines?
a. AmericandDrugdIndex
b. AmericandHospitaldFormulary
c. DailyMed
d. DrugdReference
ANS:d C
DailyMeddmakesdavailabledtodhealthcaredprovidersdanddthedpublicdadstandard,dcomprehensive,du
p-to-
datedlookdupdandddownloadabledresourcedaboutdmedicines.dThedAmericandDrugdIndexdisdnotdapp
ropriatedfordpatientduse.dThedAmericandHospitaldFormularydisdnotdappropriatedfordpatientduse.d
Theddrugdreferencedisdnotdappropriatedfordpatientd use.
DIF: CognitivedLevel:dKnowledge REF:d p.d3d|dp.d4
OBJ:d3dNAT:d NCLEXdClientdNeedsdCategory:dPhysiologicaldIntegr
ity
TOP:d NursingdProcessdStep:dImplementation
CON:d Safetyd|dPatientdEducationd|dClinicaldJudgment
6. WhichdlegislationdauthorizesdthedFDAdtoddeterminedthedsafetydofdaddrugdbeforeditsdmarketing?
a. FederaldFood,dDrug,danddCosmeticdActd(1938)
b. DurhamdHumphreydAmendmentd(1952)
, TestdBankdFordClayton’sdBasicdPharmacologydfordNursesd19thdEdition 4
c. ControlleddSubstancesdActd(1970)
d. KefauverdHarrisdDrugdAmendmentd(1962)
ANS:d A
ThedFederaldFood,dDrug,danddCosmeticdActdofd1938dauthorizeddthedFDAdtoddeterminedthedsafet
ydofdallddrugsdbeforedmarketing.dLaterdamendmentsdanddactsdhelpeddtightendFDAdcontroldandden
sureddrugdsafety.dThedDurhamdHumphreydAmendmentddefinesdthedkindsdofddrugsdthatdcannotdb
eduseddsafelydwithoutdmedicaldsupervisiondanddrestrictsdtheirdsaledtodprescriptiondbydadlicenseddp
ractitioner.dThedControlleddSubstancesdActdaddressesdonlydcontrolleddsubstancesdanddtheirdcateg
orization.dThedKefauverdHarrisdDrugdAmendmentdensuresddrugdefficacydanddgreaterddrugdsafety.
dDrugdmanufacturersdaredrequireddtodprovedtodthedFDAdthedeffectivenessdofdtheirdproductsdbefor
edmarketingdthem.
DIF: CognitivedLevel:dKnowledge REF:dp.d 5dTabledl.3
OBJ:d 5
NAT:dNCLEXdClientdNeedsdCategory:dPhysiologicaldIntegrityd
TOP:d NursingdProcessdStep:dAssessment
CON:d Safetyd|dPatientdEducationd|dEvidenced|dHealthdCaredLaw
7. Whichdclassificationddoesdmeperidined(Demerol)dfalldunder?
a. I
b. II
c. III
d. IV
ANS:d B
Meperidined(Demerol)disdadScheduledIIddrug;ditdhasdadhighdpotentialdfordabusedanddmaydleaddtodse
veredpsychologicaldanddphysicalddependence.dScheduledIddrugsdhavedhighdpotentialdfordabusedand
dnodrecognizeddmedicalduse.dScheduledIIIddrugsdhavedsomedpotentialdfordabuse.dUsedmaydleaddto
dlowdtodmoderatedphysicalddependencedordhighdpsychologicalddependence.dScheduledIVddrugsdh
avedlowdpotentialdfordabuse.dUsedmaydleaddtodlimiteddphysicaldordpsychologicalddependence.
DIF: CognitivedLevel:dKnowledge REF:d p.d10
OBJ:d2dNAT:d NCLEXdClientdNeedsdCategory:dSafe,dEffectivedCared
Environment
TOP:d NursingdProcessdStep:dAssessment CON:d PatientdEducationd|dAddictiond|dPain
8. WhichdactiondwoulddthedFDAdtakedtodexpediteddrugddevelopmentd anddapprovaldfordandoutbreakdo
fdsmallpox?
a. Listdsmallpoxdasdadhealthdorphanddisease.
b. Omitdthedpreclinicaldresearchdphase.
c. Extenddthedclinicaldresearchdphase.
d. Fastdtrackdthedinvestigationalddrug.
ANS:d D
OncedthedInvestigationaldNewdDrugdApplicationdhasdbeendapproved,dtheddrugdcandreceivedhighe
stdprioritydwithindthedagency,dwhichdisdcalleddfastdtracking.dAdsmallpoxdoutbreakdwoulddbecome
dadprioritydconcerndindthedworld.dOrphanddiseasesdarednotdresearcheddindadprioritydmanner.dPrecli
nicaldresearchdisdnotdomitted.dExtendingdanydphasedofdthedresearchdwoulddmeandadlongerdtimedtod
developdadvaccine.dThedFDAdmustdensuredthatdalldphasesdofdthedpreclinicaldanddclinicaldresearchdp
hasedhavedbeendcompleteddindadsafedmanner.
DIF: CognitivedLevel:dKnowledge REF:dddp.d7 OBJ:d 5
