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COMSAE Cramming Exam Questions and
Answers 100% Pass
Most exotoxins are heat (labile/stabile) - ANSWER ✔✔-Labile
Which exotoxins are heat stabile? - ANSWER ✔✔-S. aureus and B. cerus (enterotoxin, food poisoning, no
antibiotic treatment)
Neisseria meningitis is a gram ___ _____ - ANSWER ✔✔-negative diplococci, obligate intracellular
Bacteroides fragilis is a gram _____ strict ____ and causes _____ - ANSWER ✔✔-Gram negative strict
anaerobe and causes pelvic or bowl abscess.
Tx: metronidazole or clindamycin + surgical drainage
Culture Media: Gonorrhea - ANSWER ✔✔-Thayer-Martin (chocolate)
H. influenza - ANSWER ✔✔-Chocolate
C. diphtheria - ANSWER ✔✔-Loffler's + Tellurite
Bordetella pertussis - ANSWER ✔✔-Bordet-Gengou (Potato extract)
M. tuberculosis - ANSWER ✔✔-Loweenstein-Jensen agat
Legionella - ANSWER ✔✔-Charcoal yeast extract agar
Mycoplasma pneumoniae - ANSWER ✔✔-Eaton's agar (provides sterols)
Fungi - ANSWER ✔✔-Sabouraud's agar (contains peptides)
E. Coli - ANSWER ✔✔-EMB - eosin - methylene blue green metallic colonies
Created by Grace Amelia © 2025, All Rights Reserved.
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Lactose fermenting bacteria (enterobacter, klebsellia) - ANSWER ✔✔-MacConkey's (decreased pH
produces pink colonies)
Strep Pneumoniae is a gram ___, ______ shaped, _______ with a ______ - ANSWER ✔✔-Gram positive,
lancet-shaped, diplococci with a capsule
Causes adult bacterial meningitis and community acquired PNA
Secretes IgA proteases
Optochin-sensitive
Alpha hemolytic
Virulence factor - capsule
Cat scratch organism - ANSWER ✔✔-Bartonella, treat with azithro, DO NOT ASPIRATE
Cat bite organism - ANSWER ✔✔-Paseurella
Cat Poop - ANSWER ✔✔-Toxo gondii
Most common bacterial STD in US? - ANSWER ✔✔-Chlamydia
Rose spots on belly, constipation and diarrhea, gram negative motile bacteria with FLAGELLA and
lactose non-fermenter (produces sulfide) .... what is it? - ANSWER ✔✔-Salmonella typhoid/typhoid fever
Treat with ceftriaxone
Treat carriers with cipro or ampicillin
Resists phagocytosis via Vi polysaccharide
Rickettsia treatment for over 8yo - ANSWER ✔✔-Doxycycline
Rickettsia treatment when pregnant - ANSWER ✔✔-Chloramphenicol
Created by Grace Amelia © 2025, All Rights Reserved.
, 3|Page
Rickettsia treatment under 8 yo - ANSWER ✔✔-Amoxicillin
Rash on palm and soles which spreads to trunk, meningoencephalitis, renal failure - related to dog tick
(dermacentor) - ANSWER ✔✔-Rickettsia rickettssii (Rocky Mountain Spotted Fever)
Endemic typhus, spread by body louse, rash on trunk that spreads peripherally, maculopapular
petechiae, common in homeless - ANSWER ✔✔-Rickettsia prowazekii
Endemic typhus (murine typhus), fleas on rats, discrete rash after six days - ANSWER ✔✔-Ricketssia
typhi
Q fever, a type of rickettsia, seen in cattle farmers, severe onset fever and dry cough but NO RASH -
ANSWER ✔✔-Coxiella burnetii
Thumb print sign, drooling in child, sniffing position = - ANSWER ✔✔-epiglottis
Reactive arthritis associated with urethritis, cervicitis, and conjunctivitis (most commonly chlamydia or
shigella related) - ANSWER ✔✔-Reiter's Syndrome
Infection localized to lymphatic tissues, presents as cervical lyphadenitis in children, cured by excision
and chemotherapy - ANSWER ✔✔-Mycobacterium scrofulaceum
Treatment for non-healing skin ulcer on hands following trauma in a patient who works around fish/fish
tanks - ANSWER ✔✔-Fishtank granulomoa, mycobacterium marinum, treat with rifampin and
ethambutol
Broad based budding yeast (in tissue) and hyphae with conida (in environment) - ANSWER ✔✔-
Bloastomycosis, causes bone skin and pulmonary disease, common in midwest, treat with Amphotericin
B
Fungal ball which fills lung cavity, severe hemoptosis - ANSWER ✔✔-Aspergillis aspergilloma remove
the ball
Created by Grace Amelia © 2025, All Rights Reserved.
COMSAE Cramming Exam Questions and
Answers 100% Pass
Most exotoxins are heat (labile/stabile) - ANSWER ✔✔-Labile
Which exotoxins are heat stabile? - ANSWER ✔✔-S. aureus and B. cerus (enterotoxin, food poisoning, no
antibiotic treatment)
Neisseria meningitis is a gram ___ _____ - ANSWER ✔✔-negative diplococci, obligate intracellular
Bacteroides fragilis is a gram _____ strict ____ and causes _____ - ANSWER ✔✔-Gram negative strict
anaerobe and causes pelvic or bowl abscess.
Tx: metronidazole or clindamycin + surgical drainage
Culture Media: Gonorrhea - ANSWER ✔✔-Thayer-Martin (chocolate)
H. influenza - ANSWER ✔✔-Chocolate
C. diphtheria - ANSWER ✔✔-Loffler's + Tellurite
Bordetella pertussis - ANSWER ✔✔-Bordet-Gengou (Potato extract)
M. tuberculosis - ANSWER ✔✔-Loweenstein-Jensen agat
Legionella - ANSWER ✔✔-Charcoal yeast extract agar
Mycoplasma pneumoniae - ANSWER ✔✔-Eaton's agar (provides sterols)
Fungi - ANSWER ✔✔-Sabouraud's agar (contains peptides)
E. Coli - ANSWER ✔✔-EMB - eosin - methylene blue green metallic colonies
Created by Grace Amelia © 2025, All Rights Reserved.
,2|Page
Lactose fermenting bacteria (enterobacter, klebsellia) - ANSWER ✔✔-MacConkey's (decreased pH
produces pink colonies)
Strep Pneumoniae is a gram ___, ______ shaped, _______ with a ______ - ANSWER ✔✔-Gram positive,
lancet-shaped, diplococci with a capsule
Causes adult bacterial meningitis and community acquired PNA
Secretes IgA proteases
Optochin-sensitive
Alpha hemolytic
Virulence factor - capsule
Cat scratch organism - ANSWER ✔✔-Bartonella, treat with azithro, DO NOT ASPIRATE
Cat bite organism - ANSWER ✔✔-Paseurella
Cat Poop - ANSWER ✔✔-Toxo gondii
Most common bacterial STD in US? - ANSWER ✔✔-Chlamydia
Rose spots on belly, constipation and diarrhea, gram negative motile bacteria with FLAGELLA and
lactose non-fermenter (produces sulfide) .... what is it? - ANSWER ✔✔-Salmonella typhoid/typhoid fever
Treat with ceftriaxone
Treat carriers with cipro or ampicillin
Resists phagocytosis via Vi polysaccharide
Rickettsia treatment for over 8yo - ANSWER ✔✔-Doxycycline
Rickettsia treatment when pregnant - ANSWER ✔✔-Chloramphenicol
Created by Grace Amelia © 2025, All Rights Reserved.
, 3|Page
Rickettsia treatment under 8 yo - ANSWER ✔✔-Amoxicillin
Rash on palm and soles which spreads to trunk, meningoencephalitis, renal failure - related to dog tick
(dermacentor) - ANSWER ✔✔-Rickettsia rickettssii (Rocky Mountain Spotted Fever)
Endemic typhus, spread by body louse, rash on trunk that spreads peripherally, maculopapular
petechiae, common in homeless - ANSWER ✔✔-Rickettsia prowazekii
Endemic typhus (murine typhus), fleas on rats, discrete rash after six days - ANSWER ✔✔-Ricketssia
typhi
Q fever, a type of rickettsia, seen in cattle farmers, severe onset fever and dry cough but NO RASH -
ANSWER ✔✔-Coxiella burnetii
Thumb print sign, drooling in child, sniffing position = - ANSWER ✔✔-epiglottis
Reactive arthritis associated with urethritis, cervicitis, and conjunctivitis (most commonly chlamydia or
shigella related) - ANSWER ✔✔-Reiter's Syndrome
Infection localized to lymphatic tissues, presents as cervical lyphadenitis in children, cured by excision
and chemotherapy - ANSWER ✔✔-Mycobacterium scrofulaceum
Treatment for non-healing skin ulcer on hands following trauma in a patient who works around fish/fish
tanks - ANSWER ✔✔-Fishtank granulomoa, mycobacterium marinum, treat with rifampin and
ethambutol
Broad based budding yeast (in tissue) and hyphae with conida (in environment) - ANSWER ✔✔-
Bloastomycosis, causes bone skin and pulmonary disease, common in midwest, treat with Amphotericin
B
Fungal ball which fills lung cavity, severe hemoptosis - ANSWER ✔✔-Aspergillis aspergilloma remove
the ball
Created by Grace Amelia © 2025, All Rights Reserved.
