Examl3:lNSGl3022/lNSG3022l(NewlUpdate)l
PharmacotherapeuticslIlReview|lQsl&lAs|l
GradelA|l100%lCorrectl(VerifiedlAnswers)l–
lSouthlUniversity
QUESTION
islalprotectivelmechanismlinlwhichlthelbodylattemptsltolneutralizelandldestroylharmfullagentsla
tlthelsiteloflinjurylandltolestablishlconditionslforltissuelrepair
Answer:
lthelprocessloflinflammationlorlhowlitlworks
QUESTION
islcausedlbylmicroorganismslandlresultslinlinflammation
Answer:
linfection
QUESTION
whatlarelthelcausesloflinflammation
Answer:
linfectionltrauma
surgicallinterventionslextremelheatlorlcoldlcausticlchemicallagents
QUESTION
Whatlarelthel5lcardinallsignsloflinflammation?
Answer:
lheat,lrednessl(erythmia),lswellingl(edema),lpain,llossloflfunction
QUESTION
inhibitlchemicallmediatorslwhichldecreaseslinflammatorylprocess
,Answer:
lanti-in-lflammatorylagents
QUESTION
notlalllinfectionlequals
Answer:
linflammation
QUESTION
COX-1
Answer:
lmakeslprostaglandinslthatlactivatelplateletslandlprotectlthelstomachlandlintestinalllining
QUESTION
COX-2
Answer:
lmakeslprostaglandinslthatlpromotelpain,lfever,landlinflammation
QUESTION
COX-1landlCOX-2lform
Answer:
lprostaglandins
QUESTION
1stlGenlNSAIDS
Answer:
lsalicylates-laspirin
Propioniclacidlderiatives-ibuprofen
QUESTION
2ndlgenlNSAIDs
,Answer:
lCelecoxibl(Celebrex)
QUESTION
prostaglandinslhavelwhatleffects
Answer:
lvasodilationlrelaxationloflsmoothlmuscle
increasedlcapillarylpermeabilitylsensitizationloflnervelcellsltolpain
QUESTION
salicylateslhave
Answer:
lanti-inflammatoryleffectslantipyreticlpropertiesl(heatlreducer)
analgesiclpropertiesl(relievelpain)
QUESTION
whatlarelcontraindicationsloflsalicylatesl(NSAIDS)
Answer:
lbleedinglabnormalitieslimpairedlrenallfunction
QUESTION
aspirinleffects
Answer:
lbloodlcoagulationlgreaterlriskloflGIlbleeding
QUESTION
whatlislthelroutelofladmissionlforlaspirin
Answer:
lorallorlrectal
QUESTION
whatlshouldlalnursellookloutlforlwhenlalpatientlisltakinglaspirin?
, Answer:
ltinnituslstomachlpain
l
gilbleedinglthrombocytopenia
QUESTION
PropioniclAcidlDerivatives
Answer:
libuprofen,lnaproxenlhighlylproteinlbound
andlbetterltoleratedlthanlotherlNSAIDS
QUESTION
PropioniclAcidlDerivativeslhave
Answer:
lanti-inflammatoryleffectslanti-pyreticlproperties
analgesiclproperties
QUESTION
contraindicationsloflibuprofen
Answer:
lbleedinglissueslimpairedlrenallfunction
QUESTION
ibuprofenlincreasesltheleffectivenesslof
Answer:
lwarfarinlsulfonamides
cephalosporinslphenytoin
QUESTION
celecoxib
Answer:
lInhibitionloflthelCOX-2lenzymelisoformlislthoughtltolbelresponsiblelforlthelanti-
inflammatoryleffectsloflNSAIDs.
PharmacotherapeuticslIlReview|lQsl&lAs|l
GradelA|l100%lCorrectl(VerifiedlAnswers)l–
lSouthlUniversity
QUESTION
islalprotectivelmechanismlinlwhichlthelbodylattemptsltolneutralizelandldestroylharmfullagentsla
tlthelsiteloflinjurylandltolestablishlconditionslforltissuelrepair
Answer:
lthelprocessloflinflammationlorlhowlitlworks
QUESTION
islcausedlbylmicroorganismslandlresultslinlinflammation
Answer:
linfection
QUESTION
whatlarelthelcausesloflinflammation
Answer:
linfectionltrauma
surgicallinterventionslextremelheatlorlcoldlcausticlchemicallagents
QUESTION
Whatlarelthel5lcardinallsignsloflinflammation?
Answer:
lheat,lrednessl(erythmia),lswellingl(edema),lpain,llossloflfunction
QUESTION
inhibitlchemicallmediatorslwhichldecreaseslinflammatorylprocess
,Answer:
lanti-in-lflammatorylagents
QUESTION
notlalllinfectionlequals
Answer:
linflammation
QUESTION
COX-1
Answer:
lmakeslprostaglandinslthatlactivatelplateletslandlprotectlthelstomachlandlintestinalllining
QUESTION
COX-2
Answer:
lmakeslprostaglandinslthatlpromotelpain,lfever,landlinflammation
QUESTION
COX-1landlCOX-2lform
Answer:
lprostaglandins
QUESTION
1stlGenlNSAIDS
Answer:
lsalicylates-laspirin
Propioniclacidlderiatives-ibuprofen
QUESTION
2ndlgenlNSAIDs
,Answer:
lCelecoxibl(Celebrex)
QUESTION
prostaglandinslhavelwhatleffects
Answer:
lvasodilationlrelaxationloflsmoothlmuscle
increasedlcapillarylpermeabilitylsensitizationloflnervelcellsltolpain
QUESTION
salicylateslhave
Answer:
lanti-inflammatoryleffectslantipyreticlpropertiesl(heatlreducer)
analgesiclpropertiesl(relievelpain)
QUESTION
whatlarelcontraindicationsloflsalicylatesl(NSAIDS)
Answer:
lbleedinglabnormalitieslimpairedlrenallfunction
QUESTION
aspirinleffects
Answer:
lbloodlcoagulationlgreaterlriskloflGIlbleeding
QUESTION
whatlislthelroutelofladmissionlforlaspirin
Answer:
lorallorlrectal
QUESTION
whatlshouldlalnursellookloutlforlwhenlalpatientlisltakinglaspirin?
, Answer:
ltinnituslstomachlpain
l
gilbleedinglthrombocytopenia
QUESTION
PropioniclAcidlDerivatives
Answer:
libuprofen,lnaproxenlhighlylproteinlbound
andlbetterltoleratedlthanlotherlNSAIDS
QUESTION
PropioniclAcidlDerivativeslhave
Answer:
lanti-inflammatoryleffectslanti-pyreticlproperties
analgesiclproperties
QUESTION
contraindicationsloflibuprofen
Answer:
lbleedinglissueslimpairedlrenallfunction
QUESTION
ibuprofenlincreasesltheleffectivenesslof
Answer:
lwarfarinlsulfonamides
cephalosporinslphenytoin
QUESTION
celecoxib
Answer:
lInhibitionloflthelCOX-2lenzymelisoformlislthoughtltolbelresponsiblelforlthelanti-
inflammatoryleffectsloflNSAIDs.