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NAPSRx CNPR exam (Revised 18th Edition) Exam
Questions and Answers 100% Pass
what does a STAT order mean? - ANSWER ✔✔-a drug needed immediately and given only once
what information does the overdosage section of the labeling provide? - ANSWER ✔✔-signs, symptoms
and treatment of acute overdoses
types of drug-drug interactions: - ANSWER ✔✔-duplication, opposition (antagonism) and alteration
(p.51)
tolerance vs resistance - ANSWER ✔✔-tolerance is the diminished response to a drug; resistance is the
cells ability to resist the effects of the drug on them.
abbreviated new drug application (ANDA) - ANSWER ✔✔-the process by which applicants must
scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the
same way as the innovator drug, no duplicate testing (p. 75)
the Hatch-Waxman Act of 1984 - ANSWER ✔✔--A.K.A. Drug Price Competition and Patent Restoration
Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability
studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic cooling off
period once an ANDA is challenged for patent infringement (p. 75)
four basic transport mechanisms - ANSWER ✔✔-passive diffusion, facilitated diffusion, active transport,
and pinocytosis (p. 95)
Created by Grace Amelia © 2025, All Rights Reserved.
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potency vs efficacy - ANSWER ✔✔-potency: amount of drug necessary to produce desired effect
efficacy: magnitude of maximal response that can be received from a drug
*efficacy is almost always more important that potency* (p. 106)
the four phases of clinical trials - ANSWER ✔✔-phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) - ANSWER ✔✔-Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity - ANSWER ✔✔-reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias - ANSWER ✔✔-sampling error is unbiased and is randomly chosen from
the population.
selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
independent vs dependent variable - ANSWER ✔✔-An independent variable is the one that influences
the variation. A dependent variable is the variable being tested and measured in a scientific experiment
(the result of applying the independent variable).
Drug Utilization Review (DUR) programs - ANSWER ✔✔--involve retrospective monitoring of
physicians' prescribing patterns
-more than 90% of HMOs require DURs
-nowadays mostly monitors cost savings (p. 181)
opportunity cost - ANSWER ✔✔-based on the premise that all resources are scarce, and therefore every
time we choose to use a resource it reduces the possibility of it being used in another way.
Created by Grace Amelia © 2025, All Rights Reserved.
NAPSRx CNPR exam (Revised 18th Edition) Exam
Questions and Answers 100% Pass
what does a STAT order mean? - ANSWER ✔✔-a drug needed immediately and given only once
what information does the overdosage section of the labeling provide? - ANSWER ✔✔-signs, symptoms
and treatment of acute overdoses
types of drug-drug interactions: - ANSWER ✔✔-duplication, opposition (antagonism) and alteration
(p.51)
tolerance vs resistance - ANSWER ✔✔-tolerance is the diminished response to a drug; resistance is the
cells ability to resist the effects of the drug on them.
abbreviated new drug application (ANDA) - ANSWER ✔✔-the process by which applicants must
scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the
same way as the innovator drug, no duplicate testing (p. 75)
the Hatch-Waxman Act of 1984 - ANSWER ✔✔--A.K.A. Drug Price Competition and Patent Restoration
Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability
studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic cooling off
period once an ANDA is challenged for patent infringement (p. 75)
four basic transport mechanisms - ANSWER ✔✔-passive diffusion, facilitated diffusion, active transport,
and pinocytosis (p. 95)
Created by Grace Amelia © 2025, All Rights Reserved.
, 2|Page
potency vs efficacy - ANSWER ✔✔-potency: amount of drug necessary to produce desired effect
efficacy: magnitude of maximal response that can be received from a drug
*efficacy is almost always more important that potency* (p. 106)
the four phases of clinical trials - ANSWER ✔✔-phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) - ANSWER ✔✔-Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity - ANSWER ✔✔-reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias - ANSWER ✔✔-sampling error is unbiased and is randomly chosen from
the population.
selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
independent vs dependent variable - ANSWER ✔✔-An independent variable is the one that influences
the variation. A dependent variable is the variable being tested and measured in a scientific experiment
(the result of applying the independent variable).
Drug Utilization Review (DUR) programs - ANSWER ✔✔--involve retrospective monitoring of
physicians' prescribing patterns
-more than 90% of HMOs require DURs
-nowadays mostly monitors cost savings (p. 181)
opportunity cost - ANSWER ✔✔-based on the premise that all resources are scarce, and therefore every
time we choose to use a resource it reduces the possibility of it being used in another way.
Created by Grace Amelia © 2025, All Rights Reserved.
