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NR 507 midterm Exam Questions and Answers
100% Pass
Hives (urticaria) are an example of a: - ANSWER ✔✔-Type 1 hypersensitivity reaction.
Anaphylaxis is what type of reaction? - ANSWER ✔✔-type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune system? - ANSWER
✔✔-neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. - ANSWER ✔✔-type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - ANSWER ✔✔-IgG or IgM
Type 1 hypersensitivity reaction is mediated by - ANSWER ✔✔-IgE
Allergic asthma is an example of - ANSWER ✔✔-type 1 hypersensitivity reaction
type 2 hypersensitivity - ANSWER ✔✔-tissue specific
Primary effector cells of type 2 - ANSWER ✔✔-macrophages
Examples of type 2 reactions - ANSWER ✔✔-drug allergies, hemolytic anemia, blood transfusion
mismatch, allergies against infectious agents
Type 2 causes - ANSWER ✔✔-The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
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Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction - ANSWER ✔✔-antigen-antibody response
Where does the antibody bind to the antigen in type 3 response? - ANSWER ✔✔-in blood or body fluids
and then circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? - ANSWER ✔✔-on cell surface
Primary effector cell in type 3 - ANSWER ✔✔-neutrophils
example of type 3 reaction - ANSWER ✔✔-serum sickness
type 4 hypersensitivity reaction - ANSWER ✔✔-cell-mediated response
primary mediators of type 4 - ANSWER ✔✔-lymphocytes and macrophages
type 4 mediated by - ANSWER ✔✔-T lymphocytes and do not use antibodies
example of type 4 - ANSWER ✔✔-localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - ANSWER ✔✔-Complement damages RBC
membrane causing cell lysis.
Which of the following is the underlying pathology for hay fever? - ANSWER ✔✔-mast cell
degranulation
The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: - ANSWER ✔✔-anaphylaxis
Which of the following assessment findings would be expected in a patient who presents with urticaria? -
ANSWER ✔✔-Eosinophilia.
Created by Grace Amelia © 2025, All Rights Reserved.
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An example of a primary immunodeficiency is: - ANSWER ✔✔-Chronic Granulomatous Disease.
what is a predominant cause of secondary immune deficiencies worldwide. - ANSWER ✔✔-Malnutrition
Which of the following is an autoimmune disease? - ANSWER ✔✔-Systemic Lupus Erythematosus (SLE).
Which is true about a primary immunodeficiency? - ANSWER ✔✔-It is the result of a single gene defect.
(genetics)
Examples of secondary immunodeficiency - ANSWER ✔✔-HIV, cancer
Secondary immunodeficiency caused by - ANSWER ✔✔-external to immune system
examples of primary immunodeficiency - ANSWER ✔✔-Chronic granulomatous Disease of Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency
examples of secondary immunodeficiency - ANSWER ✔✔-Human Immunodeficiency Virus
Pneumocystis Carinii
Pneumonia
Sinus infection
Lung cancer
Select the best statement below that describes a primary immunodeficiency: - ANSWER ✔✔-Are less
common and occur due to a defect on the development of the immune system.
Cancer is a secondary immunodeficiency. - ANSWER ✔✔-true
Created by Grace Amelia © 2025, All Rights Reserved.
NR 507 midterm Exam Questions and Answers
100% Pass
Hives (urticaria) are an example of a: - ANSWER ✔✔-Type 1 hypersensitivity reaction.
Anaphylaxis is what type of reaction? - ANSWER ✔✔-type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune system? - ANSWER
✔✔-neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. - ANSWER ✔✔-type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - ANSWER ✔✔-IgG or IgM
Type 1 hypersensitivity reaction is mediated by - ANSWER ✔✔-IgE
Allergic asthma is an example of - ANSWER ✔✔-type 1 hypersensitivity reaction
type 2 hypersensitivity - ANSWER ✔✔-tissue specific
Primary effector cells of type 2 - ANSWER ✔✔-macrophages
Examples of type 2 reactions - ANSWER ✔✔-drug allergies, hemolytic anemia, blood transfusion
mismatch, allergies against infectious agents
Type 2 causes - ANSWER ✔✔-The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Created by Grace Amelia © 2025, All Rights Reserved.
,2|Page
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction - ANSWER ✔✔-antigen-antibody response
Where does the antibody bind to the antigen in type 3 response? - ANSWER ✔✔-in blood or body fluids
and then circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? - ANSWER ✔✔-on cell surface
Primary effector cell in type 3 - ANSWER ✔✔-neutrophils
example of type 3 reaction - ANSWER ✔✔-serum sickness
type 4 hypersensitivity reaction - ANSWER ✔✔-cell-mediated response
primary mediators of type 4 - ANSWER ✔✔-lymphocytes and macrophages
type 4 mediated by - ANSWER ✔✔-T lymphocytes and do not use antibodies
example of type 4 - ANSWER ✔✔-localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - ANSWER ✔✔-Complement damages RBC
membrane causing cell lysis.
Which of the following is the underlying pathology for hay fever? - ANSWER ✔✔-mast cell
degranulation
The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: - ANSWER ✔✔-anaphylaxis
Which of the following assessment findings would be expected in a patient who presents with urticaria? -
ANSWER ✔✔-Eosinophilia.
Created by Grace Amelia © 2025, All Rights Reserved.
, 3|Page
An example of a primary immunodeficiency is: - ANSWER ✔✔-Chronic Granulomatous Disease.
what is a predominant cause of secondary immune deficiencies worldwide. - ANSWER ✔✔-Malnutrition
Which of the following is an autoimmune disease? - ANSWER ✔✔-Systemic Lupus Erythematosus (SLE).
Which is true about a primary immunodeficiency? - ANSWER ✔✔-It is the result of a single gene defect.
(genetics)
Examples of secondary immunodeficiency - ANSWER ✔✔-HIV, cancer
Secondary immunodeficiency caused by - ANSWER ✔✔-external to immune system
examples of primary immunodeficiency - ANSWER ✔✔-Chronic granulomatous Disease of Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency
examples of secondary immunodeficiency - ANSWER ✔✔-Human Immunodeficiency Virus
Pneumocystis Carinii
Pneumonia
Sinus infection
Lung cancer
Select the best statement below that describes a primary immunodeficiency: - ANSWER ✔✔-Are less
common and occur due to a defect on the development of the immune system.
Cancer is a secondary immunodeficiency. - ANSWER ✔✔-true
Created by Grace Amelia © 2025, All Rights Reserved.
