NR.406.706
Neurobiology of Mental Disorders
Final Assessment (Qns & Ans)
2025
General Instructions
1. Read All Questions Carefully: Make sure you understand each question.
2. Time Management: You have a specific amount of time to complete the exam.
Keep an eye on the clock and pace yourself.
3. Allowed Materials: Only use materials that are explicitly allowed. Unauthorized
materials can lead to disqualification.
4. ANS Format: Follow the required format for your ANS. For example, multiple-
choice questions might need you to select the best ANS, while essay questions
require detailed responses.
5. Academic Integrity: Adhere to the university's honor code. Any form of cheating or
plagiarism is strictly prohibited.
6. Technical Requirements: Ensure your computer and internet connection are
stable. For online exams, you might need a webcam and microphone for proctoring
purposes.
7. Submission: Submit your ANS before the time expires. Late submissions might
not be accepted.
©2024/2025
,1. Which neurotransmitter is primarily implicated in the
pathophysiology of schizophrenia?
A) Serotonin
B) Norepinephrine
C) Dopamine
D) GABA
Correct ANS: C) Dopamine
Rationale: Hyperactivity of dopaminergic pathways,
particularly in the mesolimbic system, is associated with positive
symptoms of schizophrenia.
2. The 'diathesis-stress model' explains mental disorders as the
result of:
A) Genetic predisposition alone
B) Environmental factors alone
C) A combination of genetic predisposition and environmental
stressors
D) Neurotransmitter imbalances solely
Correct ANS: C) A combination of genetic predisposition and
environmental stressors
©2024/2025
, Rationale: This model posits that both inherited vulnerabilities
and life stressors contribute to the onset of mental disorders.
3. Selective serotonin reuptake inhibitors (SSRIs) primarily
work by:
A) Increasing dopamine levels
B) Decreasing serotonin synthesis
C) Blocking serotonin receptors
D) Inhibiting the reabsorption of serotonin
Correct ANS: D) Inhibiting the reabsorption of serotonin
Rationale: SSRIs prevent the reuptake of serotonin at the
synaptic cleft, thereby increasing its availability in the brain.
4. Which of the following is considered a primary characteristic
of bipolar disorder?
A) Lack of motivation
B) Persistent depressive episodes
C) Alternating periods of mania and depression
D) Social avoidance
Correct ANS: C) Alternating periods of mania and depression
Rationale: Bipolar disorder is characterized by fluctuations
between manic (or hypomanic) and depressive episodes.
©2024/2025
, 5. What brain region is most commonly associated with the
regulation of mood and emotions?
A) Amygdala
B) Hippocampus
C) Cerebellum
D) Medulla oblongata
Correct ANS: A) Amygdala
Rationale: The amygdala plays a pivotal role in emotional
regulation, including fear and pleasure responses.
Fill-in-the-Blank Questions
6. The main theory explaining the neurobiological basis of
depression is the _______________ hypothesis.
Correct ANS: Monoamine
Rationale: The monoamine hypothesis states that a deficiency
in key neurotransmitters like serotonin, norepinephrine, and
dopamine can lead to depression.
7. In frontotemporal dementia, the degeneration primarily affects
the _______________ and _______________ lobes.
©2024/2025
Neurobiology of Mental Disorders
Final Assessment (Qns & Ans)
2025
General Instructions
1. Read All Questions Carefully: Make sure you understand each question.
2. Time Management: You have a specific amount of time to complete the exam.
Keep an eye on the clock and pace yourself.
3. Allowed Materials: Only use materials that are explicitly allowed. Unauthorized
materials can lead to disqualification.
4. ANS Format: Follow the required format for your ANS. For example, multiple-
choice questions might need you to select the best ANS, while essay questions
require detailed responses.
5. Academic Integrity: Adhere to the university's honor code. Any form of cheating or
plagiarism is strictly prohibited.
6. Technical Requirements: Ensure your computer and internet connection are
stable. For online exams, you might need a webcam and microphone for proctoring
purposes.
7. Submission: Submit your ANS before the time expires. Late submissions might
not be accepted.
©2024/2025
,1. Which neurotransmitter is primarily implicated in the
pathophysiology of schizophrenia?
A) Serotonin
B) Norepinephrine
C) Dopamine
D) GABA
Correct ANS: C) Dopamine
Rationale: Hyperactivity of dopaminergic pathways,
particularly in the mesolimbic system, is associated with positive
symptoms of schizophrenia.
2. The 'diathesis-stress model' explains mental disorders as the
result of:
A) Genetic predisposition alone
B) Environmental factors alone
C) A combination of genetic predisposition and environmental
stressors
D) Neurotransmitter imbalances solely
Correct ANS: C) A combination of genetic predisposition and
environmental stressors
©2024/2025
, Rationale: This model posits that both inherited vulnerabilities
and life stressors contribute to the onset of mental disorders.
3. Selective serotonin reuptake inhibitors (SSRIs) primarily
work by:
A) Increasing dopamine levels
B) Decreasing serotonin synthesis
C) Blocking serotonin receptors
D) Inhibiting the reabsorption of serotonin
Correct ANS: D) Inhibiting the reabsorption of serotonin
Rationale: SSRIs prevent the reuptake of serotonin at the
synaptic cleft, thereby increasing its availability in the brain.
4. Which of the following is considered a primary characteristic
of bipolar disorder?
A) Lack of motivation
B) Persistent depressive episodes
C) Alternating periods of mania and depression
D) Social avoidance
Correct ANS: C) Alternating periods of mania and depression
Rationale: Bipolar disorder is characterized by fluctuations
between manic (or hypomanic) and depressive episodes.
©2024/2025
, 5. What brain region is most commonly associated with the
regulation of mood and emotions?
A) Amygdala
B) Hippocampus
C) Cerebellum
D) Medulla oblongata
Correct ANS: A) Amygdala
Rationale: The amygdala plays a pivotal role in emotional
regulation, including fear and pleasure responses.
Fill-in-the-Blank Questions
6. The main theory explaining the neurobiological basis of
depression is the _______________ hypothesis.
Correct ANS: Monoamine
Rationale: The monoamine hypothesis states that a deficiency
in key neurotransmitters like serotonin, norepinephrine, and
dopamine can lead to depression.
7. In frontotemporal dementia, the degeneration primarily affects
the _______________ and _______________ lobes.
©2024/2025
